Centre de Biologie Structurale

Actualités

Séminaires

16 Jan

Young CBS Researchers Meeting 16 Jan 2026 16:00 to 17:00
26 Jan

biophysics seminar: Manu 26 Jan 2026 11:00 to 12:00
26 Jan

AG 26 Jan 2026 15:30 to 16:30

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Dernières publications

HEIP1 orchestrates pro-crossover protein activity during mammalian meiosis
De Muyt A, Lee S, Khanal S, Toe LD, Adam C, Mercier R, Borde V, Hunter N, Robert T, PNAS, 2025
Fragment-based drug design of a bacterial kinase inhibitor capable of increasing the antibiotic sensitivity of clinical isolates
Kowalewski J, Deutscher R, Richardoz M, Tomaszczyk M, Gelin M, Labesse G, Hausch F, Wright GD, Dunyach-Remy C, Guichou JF, Lionne C, Commun Chem, 2025
An acyclic nucleoside phosphonate effectively blocks the egress of the malaria parasite by inhibiting the synthesis of cyclic GMP
Ali M, Dura R, Guery MA, Colard-Itte E, Cheviet T, Robresco L, Berry L, Lionne C, Lavazec C, Claessens A, Peyrottes S, Wengelnik K, Wein S, Cerdan R, Sci Adv, 2025
Identification and characterization of a nonpeptidic cyclophilin ligand with antiviral activity against feline and porcine alpha-coronaviruses
Delaplace M, Khan M, Huet H, Softic L, Ahnou N, Bigault L, Guichou JF, Ahmed-Belkacem A, Nevers Q, Le Poder S, Vet Res, 2025
Acyclic Nucleoside Phosphonates As Potential Inhibitors Of Plasmodium Falciparum Egress
Cheviet T, Wein S, Lionne C, Badji Y, Venturini N, Cerdan R, Peyrottes S, Chemistry, 2025
An innovative in situAFM system for a soft X-ray spectromicroscopy synchrotron beamline
Hafner A, Costa L, Kourousias G, Bonanni V, Zizic M, Stolfa A, Bazi B, Vincze L, Gianoncelli A, Analyst, 2025
New structural insights into the control of the retinoic acid receptors RAR/RXR by DNA, ligands, and transcriptional coregulators
Tambones I, Sagar A, Vankova P, Loginov D, Carivenc C, Rochel N, Bourguet W, Man P, Bernado P, le Maire A, Nucleic Acids Res, 2025
Insertion of Fluorescent Proteins Near the Plug Domain of MotB Generates Functional Stator Complexes
Gurung JP, Ridone P, Biquet-Bisquert A, Bryant G, Pedaci F, Nord AL, Baker MAB, Microbiologyopen, 2025
Polysomes and mRNA control the biophysical properties of the eukaryotic cytoplasm
Gade VR, Heinrich S, Paloni M, Gomez-Garcia PA, Dzanko A, Oswald A, Marchand D, Khawaja S, Barducci A, Weis K, Cell Rep, 2025
Signature of cooperativity in the stochastic fluctuations of small systems with application to the bacterial flagellar motor
Franco-Onate MJ, Parmeggiani A, Dorignac J, Geniet F, Walter JC, Pedaci F, Nord AL, Palmeri J, Walliser NO, Sci Rep, 2025
Targeting pregnane X receptor with a potent agonist-based PROTAC to delay colon cancer relapse
Bansard L, Laconde G, Delfosse V, Huet T, Ayeul M, Rigal E, Donati Q, Gerbal-Chaloin S, Daujat-Chavanieu M, Brunel L, Legrand B, Chavanieu A, Martin AR, Pannequin J, Bourguet W, Amblard M, Pascussi JM, Oncogenesis, 2025
Zymoseptoria tritici Effectors Structurally Related to Killer Proteins UmV-KP4 and UmV-KP6 Inhibit Fungal Growth, and Define Extended Protein Families in Fungi
deGuillen K, Mammri L, Gracy J, Padilla A, Barthe P, Hoh F, Lahfa M, Rouffet J, Petit-Houdenot Y, Kroj T, Lebrun MH, Mol Plant Pathol, 2025
Uniaxial cyclic stretch regulates the expression of thrombomodulin and von Willebrand factor on endothelial cells
Giannetti A, Genot E, Perez-Martin A, Faure E, Gris JC, Cardoso M, Goze-Bac C, Benistant C, Abkarian M, Blood Vessel Thromb Hemost, 2025
FAIR sharing of Chromatin Tracing datasets using the newly developed 4DN FISH Omics Format
Navelkar R, Cosolo A, Bintu B, Cheng Y, Gardeux V, Gutnik S, Fujimori T, Hafner A, Jay A, Jia BB, Jussila AP, Llimos G, Lioutas A, Martins NMC, Moore WJ, Takei Y, Wong F, Yang K, Zhang H, Zhu Q, Bienko M, Bintu L, Cai L, Deplancke B, Nollmann M, Mango SE, Ren B, Park PJ, Sawh AN, Schroeder A, Swedlow JR, Vahedi G, Wu CT, Aufmkolk S, Boettiger AN, Farabella I, Strambio-De-Castillia C, Wang S, ArXiv, 2025
Imaging Nuclear Envelopes Using Correlative AFM/Fluorescence Microscopy
Costes E, Vial A, Doucet C, Milhiet PE, Methods Mol Biol, 2025
Automated identification of honey bee pollen loads for field-applied palynological studies
Bares J, Poncelet P, Doucet CM, Legrand C, Cambon A, Carlier C, Chevin P, Dewaele LP, Jullien D, Thibaud JB, Charnet P, Rousset M, Cheptou PO, New Phytol, 2025
Dissecting rifampicin heteroresistance in Mycobacterium tuberculosis: integrating whole-genome sequencing with phenotypic and clonal validation
Vallejos-Sanchez K, Taquiri-Diaz DA, Romero-Rodriguez OA, Vargas-Ruiz AP, Coronel J, Torres A, Perez-Martinez JL, Ochoa-Ortiz A, Gilman RH, Grandjean L, Cohen-Gonsaud M, Zimic M, Sheen P, J Med Microbiol, 2025
Neutral peptides allow aggregation of cationic peptides in antimicrobial secretory fluids
Petkov P, Marinova R, Litov L, Sirakova P, Lilkova E, Kamburova K, Krachmarova E, Taneva S, Allemand F, Mouhand A, Thureau A, Sibille N, Ilieva N, Biochem Biophys Res Commun, 2025
Selective Ion Binding and Uptake Shape the Microenvironment of Biomolecular Condensates
Smokers IBA, Lavagna E, Freire RVM, Paloni M, Voets IK, Barducci A, White PB, Khajehpour M, Spruijt E, J Am Chem Soc, 2025
In situ structure of a bacterial flagellar motor at subnanometre resolution reveals adaptations for increased torque
Drobnic T, Cohen EJ, Calcraft T, Alzheimer M, Froschauer K, Svensson S, Hoffman WH, Singh N, Garg SG, Henderson LD, Umrekar TR, Nans A, Ribardo D, Pedaci F, Nord AL, Hochberg GKA, Hendrixson DR, Sharma CM, Rosenthal PB, Beeby M, Nat Microbiol, 2025
Sequence- and Docking-Site-Dependent Contributions to Multi-Site Phosphorylation of an Intrinsically Disordered MAPK Substrate
Orand T, Delaforge E, Chenal M, Tengo M, Herrmann T, Cortes J, Bernado P, Jensen MR, Adv Sci (Weinh), 2025
The dependence of the amino acid backbone conformation on the translated synonymous codon is not statistically significant
Gonzalez-Delgado J, Mier P, Bernado P, Neuvial P, Cortes J, Proc Natl Acad Sci U S A, 2025
A coiled-coil domain triggers oligomerization of MmpL10, the mycobacterial transporter of trehalose polyphleate precursor
Couston J, Feuillard J, Ancelin A, Lai-Kee-Him J, Brodolin K, Chalut C, Gourdon P, Blaise M, FEBS Lett, 2025
Lipids modulate the dynamics of GPCR:beta-arrestin interaction
Gomes AAS, Di Michele M, Roessner RA, Damian M, Bisch PM, Sibille N, Louet M, Baneres JL, Floquet N, Nat Commun, 2025
Picomolar bivalent inhibitors of protein kinase CK2 active against beta-coronavirus replication
Grenier D, Lopez Molina DS, Gelin M, Mularoni A, Guichou JF, Delcros JG, Martinasso C, Yang Y, Ahnou N, Pawlotsky JM, Ahmed-Belkacem A, Krimm I, Eur J Med Chem, 2025
Rational Design and Synthesis of Highly Stable Haloflavanone DNA Methyltransferase Inhibitors Inducing Tumor Suppressor Gene Re-expression in Cancer Cells
Calzaferri F, Daher H, Gilbert J, Yang Y, Tauziet M, Jallet C, Bessin Y, van der Lee A, Arimondo PB, Krimm I, Julien E, Lopez M, J Med Chem, 2025
Redefining enhancer action: Insights from structural, genomic, and single-molecule perspectives
Lleres D, Gizzi AC, Nollmann M, Curr Opin Cell Biol, 2025
Triple Labeling Resolves a GPCR Intermediate State by Using Three-Color Single Molecule FRET
Bonhomme L, Bilgen E, Clerte C, Pin JP, Rondard P, Margeat E, Lamb DC, Quast RB, J Am Chem Soc, 2025
Editorial overview: Emerging perspectives in genome architecture and gene regulation
Nollmann M, Hansen AS, Curr Opin Genet Dev, 2025
Structural and Functional Characterization of the 28kDa Structured Core of BmSA1, the Major Surface Antigen of Babesia Microti
Mouhand A, Pissarra J, Barthe P, Roumestand C, Delbecq S, Proteins, 2025

Voir toutes les publications

Les équipes du CBS

Structure, dynamique et fonctions des biomolécules par RMN

Christian Roumestand et Nathalie Declerck
Structure et fonction de protéines hautement flexibles

Pau Bernadó et Nathalie Sibille
Biologie structurale multi-échelles (BSME)

Patrick Bron
Atelier de Biologie-Chimie-Informatique Structurale

Gilles Labesse
Les récepteurs nucléaires, intégrateurs de signaux endogènes et environnementaux

William Bourguet et Albane Le Maire
Modélisation moléculaire multi-échelle

Alessandro Barducci
Mécanismes de la ségrégation de l’ADN et du remodelage

Marcelo Nollmann
Physique et mécanique des systèmes biologiques

Manouk Abkarian et Francesco Pedaci
Biophysique Intégrative des Membranes

Pierre-Emmanuel Milhiet et Emmanuel Margeat
Biologie Synthétique

Jérôme Bonnet et Martin Cohen-Gonsaud
Modélisation moléculaire multi-échelle

Alessandro Barducci
Structure du chromosome et recombinaison en méiose

Thomas Robert
Génomique fonctionnelle et synthétique

Guillaume Cambray
Structure et fonction du récepteur AhR

Jakub Gruszczyk

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