Emplois

  • Chaire Junior CNRS en Microscopie Cryo-Electronique

    APPEL A CANDIDATURES

    CHAIRE JUNIOR CNRS en MICROSCOPIE CRYO-ELECTRONIQUE

    Le CBS propose un poste de responsable d'équipe en biologie structurale cellulaire pour un spécialiste en cryo-microscopie électronique, cryo-tomographie et approches corrélatives.

    Ce recrutement s'effectue dans le cadre d'une « Chaire Junior », soutenu par le CNRS. Le contrat est d'une durée de 5 ans et s'accompagne d'un forfait de départ de 575 k€. Le salaire annuel brut est compris entre 54600 et 57800 €, selon l'expérience professionnelle.

    Pour plus d'informations sur l'environnement scientifique et le processus de recrutement, merci de contacter le directeur du CBS, Pierre Emmanuel Milhiet (Cette adresse e-mail est protégée contre les robots spammeurs. Vous devez activer le JavaScript pour la visualiser.). Les candidatures doivent lui être envoyées par e-mail, y compris CV, liste des publications, noms de 3 référents et lettre de motivation.

    Plus d'infos ici

     

  • Positions Doctorale et Post-Doctorale sur la modélisation moléculaire des condensats cellulaires au Centre de Biologie Structurale (CBS) à Montpellier

    CALL FOR APPLICATIONS
    PhD and POSTDOCTORAL POSITION
    S
    AT CENTER FOR STRUCTURAL BIOLOGY (CBS)
    IN M
    ONTPELLIER, FRANCE

    A 3-year PhD fellowship and a 2-year postdoctoral position are available in our team at the CBS Montpellier (France) starting from autumn 2022. The positions are funded by the French National research Agency (ANR) within the BioTop (PhD) and Prospero (PostDoc) projects.


    Both these collaborative projects aim at combining a variety of experimental techniques in biophysics and molecular/cellular biology with theoretical modelling for characterizing the functional, structural and mechanical properties of cellular condensates. Biomolecular condensates arising from the phase separation of proteins and/or nucleic acids are presently recognized to play a key role in organizing cellular environment and they are attracting a huge and ever-increasing attention in disparate fields
    ranging from soft-matter physics to physiology.

     

  • Position Post-Doctorale de 2 ans au Centre de Biologie Structurale (CBS) à Montpellier (2)

    CALL FOR APPLICATIONS
    POSTDOCTORAL POSITION

    2
    YEARS POSTDOCTORAL POSITION AT CENTER FOR STRUCTURAL BIOLOGY (CBS) IN
    M
    ONTPELLIER, FRANCE


    Dr. Luca Costa

    Integrative Biophysics of Membranes (IBM) Team

    S
    CIENTIFIC PROJECT AND JOB DESCRIPTION:

    ELF3 plant proteins have the ability to undergo phase-change in response to environmental signals, such as temperature, enabling these proteins to act as developmental switches1. Phase-change occurs through dynamic compartmentalization into biomolecular condensates during the formation of Liquid-Liquid Phase Separation (LLPS) droplets. Their structure and the associated dynamics are usually assessed by Fluorescence Correlation Spectroscopy (FCS), FRAP or SAXS. However, they are
    still poorly understood at the molecular level because nanometer-resolved images of the condensates are very challenging to obtain by means of conventional microscopy methods.
     
    Our goal is to study the structure and the associated dynamics of LLPS condensates with high spatial-temporal resolution by High-Speed Atomic Force Microscopy (HS-AFM), FCS and Fluorescence Lifetime Imaging (FLIM). With its minimal invasiveness, HS-AFM will be employed to catch single proteins diffusing at the LLPS interface, enabling the characterization of the intermolecular interactions. Results will be correlated with X-Ray (SAXS) and Electron Microscopy (EM) structural
    data, as well as with theoretical models and simulations performed by our collaborators.
     

     

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Stages

stages2

Le CBS accueille chaque année de nombreux stagiaires de tout niveau, de la 3ème au post-doctorat. Les candidatures (CV et lettre de motivation) sont à adresser directement aux chercheurs des équipes du CBS.

Le recrutement des étudiants en Thèse se fait par l'intermédiaire de l'Ecole Doctorale CBS2.

Les sujets de Thèse proposés par les chercheurs du CBS sont à consulter ici.

 

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