Centre de Biologie Structurale

Actualités

Séminaires

03 Fév

CryoEM user meeting 03 Fév 2023 12:30 to 13:30
03 Fév

Young CBS Researchers Meeting 03 Fév 2023 16:00 to 17:00
06 Fév

CE CBS 06 Fév 2023 10:00 to 11:00

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Dernières publications

Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization
Morichaud Z, Trapani S, Vishwakarma RK, Chaloin L, Lionne C, Lai-Kee-Him J, Bron P, Brodolin K, Nat Commun, 2023
Structure-guided mutagenesis of the capsid protein indicates that a nanovirus requires assembled viral particles for systemic infection
Trapani S, Bhat EA, Yvon M, Lai-Kee-Him J, Hoh F, Vernerey MS, Pirolles E, Bonnamy M, Schoehn G, Zeddam JL, Blanc S, Bron P, PLoS Pathog, 2023
The Syp1/FCHo2 protein induces septin filament bundling through its intrinsically disordered domain
Ibanes S, El-Alaoui F, Lai-Kee-Him J, Cazevieille C, Hoh F, Lyonnais S, Bron P, Cipelletti L, Picas L, Piatti S, Cell Rep, 2022
Mechanical DNA Origami to Investigate Biological Systems
Mills A, Aissaoui N, Finkel J, Elezgaray J, Bellot G, Adv Biol (Weinh), 2022
Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria
Clement DA, Gelin M, Leseigneur C, Huteau V, Mondange L, Pons JL, Dussurget O, Lionne C, Labesse G, Pochet S, Eur J Med Chem, 2022
TOPOVIBL-REC114 interaction regulates meiotic DNA double-strand breaks
Nore A, Juarez-Martinez AB, Clement J, Brun C, Diagouraga B, Laroussi H, Grey C, Bourbon HM, Kadlec J, Robert T, de Massy B, Nat Commun, 2022
Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex
Gruszczyk J, Grandvuillemin L, Lai-Kee-Him J, Paloni M, Savva CG, Germain P, Grimaldi M, Boulahtouf A, Kwong HS, Bous J, Ancelin A, Bechara C, Barducci A, Balaguer P, Bourguet W, Nat Commun, 2022
The sequence context in poly-alanine regions: structure, function and conservation
Mier P, Elena-Real CA, Cortes J, Bernado P, Andrade-Navarro MA, Bioinformatics, 2022
Disentangling polydisperse biomolecular systems by Chemometrics decomposition of SAS data
Sagar A, Bernado P, Methods Enzymol, 2022
Statistical proofs of the interdependence between nearest neighbor effects on polypeptide backbone conformations
Gonzalez-Delgado J, Bernado P, Neuvial P, Cortes J, J Struct Biol, 2022
Computational Methods for the Design of Recombinase Logic Circuits with Adaptable Circuit Specifications
Zuniga A, Bonnet J, Guiziou S, Methods Mol Biol, 2022
eIF4G1 N-terminal intrinsically disordered domain is a multi-docking station for RNA, Pab1, Pub1, and self-assembly
Chaves-Arquero B, Martinez-Lumbreras S, Sibille N, Camero S, Bernado P, Jimenez M, Zorrilla S, Perez-Canadillas JM, Front Mol Biosci, 2022
Multiple parameters shape the 3D chromatin structure of single nuclei at the doc locus in Drosophila
Goetz M, Messina O, Espinola S, Fiche JB, Nollmann M, Nat Commun, 2022
Multiple parameters shape the 3D chromatin structure of single nuclei at the doc locus in Drosophila
Gotz M, Messina O, Espinola S, Fiche JB, Nollmann M, Nat Commun, 2022
Structure-based design, synthesis and biological evaluation of a NAD+analogue targeting Pseudomonas aeruginosa NAD kinase
Rahimova R, Nogaret P, Huteau V, Gelin M, Clement DA, Labesse G, Pochet S, Blanc-Potard AB, Lionne C, FEBS J, 2022
Magneto-Induced Hyperthermia and Temperature Detection in Single Iron Oxide Core-Silica/Tb3+/Eu3+(Acac) Shell Nano-Objects
Nigoghossian K, Bouvet B, Felix G, Sene S, Costa L, Milhet PE, Carneiro Neto AN, Carlos LD, Oliviero E, Guari Y, Larionova J, Nanomaterials (Basel), 2022
Structure of the vasopressin hormone-V2 receptor-beta-arrestin1 ternary complex
Bous J, Fouillen A, Orcel H, Trapani S, Cong X, Fontanel S, Saint-Paul J, Lai-Kee-Him J, Urbach S, Sibille N, Sounier R, Granier S, Mouillac B, Bron P, Sci Adv, 2022
A rapid and standardized workflow for functional assessment of bacterial biosensors in fecal samples
Zuniga A, Munoz-Guamuro G, Boivineau L, Mayonove P, Conejero I, Pageaux GP, Altwegg R, Bonnet J, Front Bioeng Biotechnol, 2022
A rapid and standardized workflow for functional assessment of bacterial biosensors in fecal samples
Zfaniga A, Munoz-Guamuro G, Boivineau L, Mayonove P, Conejero I, Pageaux GP, Altwegg R, Bonnet J, Front Bioeng Biotechnol, 2022
Evaluating and mitigating clinical samples matrix effects on TX-TL cell-free performance
Voyvodic PL, Conejero I, Mesmoudi K, Renard E, Courtet P, Cattoni DI, Bonnet J, Sci Rep, 2022
Viro-fluidics: Real-time analysis of virus production kinetics at the single-cell level
Eid J, Socol M, Naillon A, Feuillard J, Ciandrini L, Margeat E, Charlot B, Mougel M, Biophys Rep (N Y), 2022
Low Complexity Induces Structure in Protein Regions Predicted as Intrinsically Disordered
Goncalves-Kulik M, Mier P, Kastano K, Cortes J, Bernado P, Schmid F, Andrade-Navarro MA, Biomolecules, 2022
Conformational buffering underlies functional selection in intrinsically disordered protein regions
Gonzalez-Foutel NS, Glavina J, Borcherds WM, Safranchik M, Barrera-Vilarmau S, Sagar A, Estana A, Barozet A, Garrone NA, Fernandez-Ballester G, Blanes-Mira C, Sanchez IE, de Prat-Gay G, Cortes J, Bernado P, Pappu RV, Holehouse AS, Daughdrill GW, Chemes LB, Nat Struct Mol Biol, 2022
Cell-Free Protein Synthesis from Exonuclease-Deficient Cellular Extracts Utilizing Linear DNA Templates
Sabeti Azad M, Cardoso Batista A, Faulon JL, Beisel CL, Bonnet J, Kushwaha M, J Vis Exp, 2022
PYK2 senses calcium through a disordered dimerization and calmodulin-binding element
Momin AA, Mendes T, Barthe P, Faure C, Hong S, Yu P, Kadare G, Jaremko M, Girault JA, Jaremko , Arold ST, Commun Biol, 2022
Design and in vitro characterization of RXR variants as tools to investigate the biological role of endogenous rexinoids
le Maire A, Rey M, Vivat V, Guee L, Blanc P, Malosse C, Chamot-Rooke J, Germain P, Bourguet W, J Mol Endocrinol, 2022
PeroxiHUB: A Modular Cell-Free Biosensing Platform Using H₂O₂as Signal Integrator
Soudier P, Zuniga A, Duigou T, Voyvodic PL, Bazi-Kabbaj K, Kushwaha M, Vendrell JA, Solassol J, Bonnet J, Faulon JL, ACS Synth Biol, 2022
Unravelling the Adaptation Mechanisms to High Pressure in Proteins
Calio A, Dubois C, Fontanay S, Koza MM, Hoh F, Roumestand C, Oger P, Peters J, Int J Mol Sci, 2022
A modular spring-loaded actuator for mechanical activation of membrane proteins
Mills A, Aissaoui N, Maurel D, Elezgaray J, Morvan F, Vasseur JJ, Margeat E, Quast RB, Lai-Kee-Him J, Saint N, Benistant C, Nord A, Pedaci F, Bellot G, Nat Commun, 2022
Crystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation
Mary C, Soflaee MH, Kesavan R, Gelin M, Brown H, Zacharias G, Mathews TP, Lemoff A, Lionne C, Labesse G, Hoxhaj G, Mol Cell, 2022

Voir toutes les publications

Les équipes du CBS

Structure, dynamique et fonctions des biomolécules par RMN

Christian Roumestand et Nathalie Declerck
Structure et fonction de protéines hautement flexibles

Pau Bernadó et Nathalie Sibille
Biologie structurale multi-échelles (BSME)

Patrick Bron
Atelier de Biologie-Chimie-Informatique Structurale

Gilles Labesse
Les récepteurs nucléaires, intégrateurs de signaux endogènes et environnementaux

William Bourguet et Albane Le Maire
Modélisation moléculaire multi-échelle

Alessandro Barducci
Mécanismes de la ségrégation de l’ADN et du remodelage

Marcelo Nollmann
Physique et mécanique des systèmes biologiques

Manouk Abkarian et Francesco Pedaci
Biophysique Intégrative des Membranes

Pierre-Emmanuel Milhiet et Emmanuel Margeat
Biologie Synthétique

Jérôme Bonnet et Martin Cohen-Gonsaud
Modélisation moléculaire multi-échelle

Alessandro Barducci
Structure du chromosome et recombinaison en méiose

Thomas Robert
Génomique fonctionnelle et synthétique

Guillaume Cambray
Structure et fonction du récepteur AhR

Jakub Gruszczyk

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