Centre de Biologie Structurale

 
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  • 06 May
    Conseil de Direction 06 May 2025 02:00 PM to 04:00 PM

  • 12 May
    Biophysics Seminar: Manu/Pem team 12 May 2025 11:00 AM to 12:00 PM

  • 13 May
    Introductory course on fluid mechanics & microfluidics -VI-Manouk Abkarian 13 May 2025 12:30 PM to 01:45 PM

  • 06 May - 13 May
  • 13 May - 15 May
  • 16 May - 22 May
  • 23 May - 02 Jun
  • 03 Jun - 06 Jun
  • 10 Jun - 16 Jun
  • 19 Jun - 20 Jun

Latest publications

Cryo Electron Microscopy

Platform

Cryo Electron Microscopy

Technical manager Joséphine Lai Kee Him
Scientific manager Martin Cohen-Gonsaud

During the last years, a revolution occurred in the EM field (stability of electron microscopes, advances in detector hardware and image-processing software) leading to determination of complex molecular structures at high resolution. Therefore, near-atomic-resolution cryoEM structures can now be obtained for even the most challenging targets in structural biology.

 
Examples of CryoEM samples observed. A : Purified CaMV (Cauliflower Mosaic Virus). B : Mixture of bacteriophages and TMV (Tobacco Mosaic Virus). C : Magnetic core silicium nanoparticles covered with a lipid bilayer. D : Treated polymers.
 
Services

Structural analysis of frozen hydrated single particles

 

(Cryo) Electron tomography

 

Micro electron diffraction

 

Analysis or screening of negative stained sample


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  Negative stain
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