Liste des publications

2024

• Split Reporters Facilitate Monitoring of Gene Expression and Peptide Production in Linear Cell-Free Transcription-Translation Systems

  Levrier A, Capin J, Mayonove P, Karpathakis II, Voyvodic P, DeVisch A, Zuniga A, Cohen-Gonsaud M, Cabantous S, Noireaux V, Bonnet J, ACS Synth Biol, 2024

2023

• SecretoMyc, a web-based database on mycobacteria secreted proteins and structure-based homology identification using bio-informatics tools

  Gracy J, Vallejos-Sanchez K, Cohen-Gonsaud M, Tuberculosis (Edinb), 2023

• A Mycobacterium tuberculosis Effector Targets Mitochondrion, Controls Energy Metabolism, and Limits Cytochrome cExit

  Martin M, deVisch A, Boudehen YM, Barthe P, Gutierrez C, Turapov O, Aydogan T, Heriaud L, Gracy J, Neyrolles O, Mukamolova GV, Letourneur F, Cohen-Gonsaud M, Microbiol Spectr, 2023

2022

• Cryo-EM structure of transcription termination factor Rho from Mycobacterium tuberculosis reveals bicyclomycin resistance mechanism

  Saridakis E, Vishwakarma R, Lai-Kee-Him J, Martin K, Simon I, Cohen-Gonsaud M, Coste F, Bron P, Margeat E, Boudvillain M, Commun Biol, 2022

• Differentially Optimized Cell-Free Buffer Enables Robust Expression from Unprotected Linear DNA in Exonuclease-Deficient Extracts

  Batista AC, Levrier A, Soudier P, Voyvodic PL, Achmedov T, Reif-Trauttmansdorff T, DeVisch A, Cohen-Gonsaud M, Faulon JL, Beisel CL, Bonnet J, Kushwaha M, ACS Synth Biol, 2022

2021

• Programmable receptors enable bacterial biosensors to detect pathological biomarkers in clinical samples

  Chang HJ, Zuniga A, Conejero I, Voyvodic PL, Gracy J, Fajardo-Ruiz E, Cohen-Gonsaud M, Cambray G, Pageaux GP, Meszaros M, Meunier L, Bonnet J, Nat Commun, 2021

• The study of the determinants controlling Arpp19 phosphatase-inhibitory activity reveals an Arpp19/PP2A-B55 feedback loop

  Labbe JC, Vigneron S, Mechali F, Robert P, Roque S, Genoud C, Goguet-Rubio P, Barthe P, Labesse G, Cohen-Gonsaud M, Castro A, Lorca T, Nat Commun, 2021

2019

• Protein kinase B controls Mycobacterium tuberculosis growth via phosphorylation of the transcriptional regulator Lsr2 at threonine 112

  Alqaseer K, Turapov O, Barthe P, Jagatia H, De Visch A, Roumestand C, Wegrzyn M, Bartek IL, Voskuil MI, O'Hare HM, Ajuh P, Bottrill AR, Witney AA, Cohen-Gonsaud M, Waddell SJ, Mukamolova GV, Mol Microbiol, 2019

• Structural basis for chemically-induced homodimerization of a single domain antibody

  Lesne J, Chang HJ, De Visch A, Paloni M, Barthe P, Guichou JF, Mayonove P, Barducci A, Labesse G, Bonnet J, Cohen-Gonsaud M, Sci Rep, 2019

2018

• Two Faces of CwlM, an Essential PknB Substrate, in Mycobacterium tuberculosis

  Turapov O, Forti F, Kadhim B, Ghisotti D, Sassine J, Straatman-Iwanowska A, Bottrill AR, Moynihan PJ, Wallis R, Barthe P, Cohen-Gonsaud M, Ajuh P, Vollmer W, Mukamolova GV, Cell Rep, 2018

• Culex pipiens crossing type diversity is governed by an amplified and polymorphic operon of Wolbachia

  Bonneau M, Atyame C, Beji M, Justy F, Cohen-Gonsaud M, Sicard M, Weill M, Nat Commun, 2018

• A modular receptor platform to expand the sensing repertoire of bacteria

  Chang HJ, Mayonove P, Zavala A, De Visch A, Minard P, Cohen-Gonsaud M, Jerome B, ACS Synth Biol, 2018

2017

• LppM impact on the colonization of macrophages by Mycobacterium tuberculosis

  Deboosere N, Iantomasi R, Queval CJ, Song OR, Deloison G, Jouny S, Debrie AS, Chamaillard M, Nigou J, Cohen-Gonsaud M, Locht C, Brodin P, Veyron-Churlet R, Cell Microbiol, 2017

2016

• Phosphorylation-mediated regulation of the Staphylococcus aureus secreted tyrosine phosphatase PtpA

  Brelle S, Baronian G, Huc-Brandt S, Zaki LG, Cohen-Gonsaud M, Bischoff M, Molle V, Biochem Biophys Res Commun, 2016

• Mycobacterium tuberculosis LppM Displays an Original Structure and Domain Composition Linked to a Dual Localization

  Barthe P, Veyron-Churlet R, de Visch A, Gilleron M, Saliou JM, Tomavo S, Nigou J, Brodin P, Cohen-Gonsaud M, Structure, 2016

2015

• Phosphorylation of Mycobacterium tuberculosis ParB Participates in Regulating the ParABS Chromosome Segregation System

  Baronian G, Ginda K, Berry L, Cohen-Gonsaud M, Zakrzewska-Czerwinska J, Jakimowicz D, Molle V, PLoS ONE, 2015

• The external PASTA domain of the essential serine/threonine protein kinase PknB regulates mycobacterial growth

  Turapov O, Loraine J, Jenkins CH, Barthe P, McFeely D, Forti F, Ghisotti D, Hesek D, Lee M, Bottrill AR, Vollmer W, Mobashery S, Cohen-Gonsaud M, Mukamolova GV, Open Biol, 2015

2014

• A novel mode of regulation of the Staphylococcus aureus Vancomycin-resistance-associated response regulator VraR mediated by Stk1 protein phosphorylation

  Canova MJ, Baronian G, Brelle S, Cohen-Gonsaud M, Bischoff M, Molle V, Biochem Biophys Res Commun, 2014

• The RpfC (Rv1884) atomic structure shows high structural conservation within the resuscitation-promoting factor catalytic domain

  Chauviac FX, Robertson G, Quay DH, Bagneris C, Dumas C, Henderson B, Ward J, Keep NH, Cohen-Gonsaud M, Acta Crystallogr F Struct Biol Commun, 2014

• Antimicrobial treatment improves mycobacterial survival in nonpermissive growth conditions

  Turapov O, Waddell SJ, Burke B, Glenn S, Sarybaeva AA, Tudo G, Labesse G, Young DI, Young M, Andrew PW, Butcher PD, Cohen-Gonsaud M, Mukamolova GV, Antimicrob Agents Chemother, 2014

• Oleoyl-Coenzyme A Regulates Interaction of Transcriptional Regulator RaaS (Rv1219c) with DNA in Mycobacteria

  Turapov O, Waddell SJ, Burke B, Glenn S, Sarybaeva AA, Tudo G, Labesse G, Young DI, Young M, Andrew PW, Butcher PD, Cohen-Gonsaud M, Mukamolova GV, J Biol Chem, 2014

• Chromatin Insulator Factors Involved in Long-Range DNA Interactions and Their Role in the Folding of the Drosophila Genome

  Vogelmann J, Le Gall A, Dejardin S, Allemand F, Gamot A, Labesse G, Cuvier O, Negre N, Cohen-Gonsaud M, Margeat E, Nollmann M, PLoS Genet, 2014

2013

• Mycobacterium tuberculosis S-adenosyl-l-homocysteine hydrolase is negatively regulated by Ser/Thr phosphorylation

  Corrales RM, Leiba J, Cohen-Gonsaud M, Molle V, Kremer L, Biochem Biophys Res Commun, 2013

• Equivalence between Euler angle conventions for the description of tensorial interactions in liquid NMR: application to different software programs

  Dosset P, Barthe P, Cohen-Gonsaud M, Roumestand C, Demene H, J Biomol NMR, 2013

2012

• A novel mode of regulation of the Staphylococcus aureus catabolite control protein A (CcpA) mediated by Stk1 protein phosphorylation.

  Leiba J, Hartmann T, Cluzel ME, Cohen-Gonsaud M, Delolme F, Bischoff M, Molle V, J. Biol. Chem., 2012

• The C-terminal domain of the virulence factor MgtC is a divergent ACT domain.

  Yang Y, Labesse G, Carrere-Kremer S, Esteves K, Kremer L, Cohen-Gonsaud M, Blanc-Potard AB, J. Bacteriol., 2012

2011

• Structural insight into the Mycobacterium tuberculosis Rv0020c protein and its interaction with the PknB kinase

  Roumestand C, Leiba J, Galophe N, Margeat E, Padilla A, Bessin Y, Barthe P, Molle V, Cohen-Gonsaud M, Structure, 2011

2010

• The structure of PknB extracellular PASTA domain from mycobacterium tuberculosis suggests a ligand-dependent kinase activation

  Barthe P, Mukamolova GV, Roumestand C, Cohen-Gonsaud M, Structure, 2010

• Phosphorylation of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein reductase MabA regulates mycolic acid biosynthesis

  Veyron-Churlet R, Zanella-Cleon I, Cohen-Gonsaud M, Molle V, Kremer L, J Biol Chem, 2010

2009

• Dynamic and structural characterization of a bacterial FHA protein reveals a new autoinhibition mechanism

  Barthe P, Roumestand C, Canova MJ, Kremer L, Hurard C, Molle V, Cohen-Gonsaud M, Structure, 2009

• The Mycobacterium tuberculosis Ser/Thr kinase substrate Rv2175c is a DNA-binding protein regulated by phosphorylation

  Cohen-Gonsaud M, Barthe P, Canova MJ, Stagier-Simon C, Kremer L, Roumestand C, Molle V, J Biol Chem, 2009

2008

• The Mycobacterium tuberculosis serine/threonine kinase PknL phosphorylates Rv2175c: mass spectrometric profiling of the activation loop phosphorylation sites and their role in the recruitment of Rv2175c

  Canova MJ, Veyron-Churlet R, Zanella-Cleon I, Cohen-Gonsaud M, Cozzone AJ, Becchi M, Kremer L, Molle V, Proteomics, 2008

2007

• Lack of dynamics in the MabA active site kills the enzyme activity: practical consequences for drug-design studies

  Poncet-Montange G, Ducasse-Cabanot S, Quemard A, Labesse G, Cohen-Gonsaud M, Acta Crystallogr D Biol Crystallogr, 2007

2006

• Bacterial resuscitation factors: revival of viable but non-culturable bacteria

  Keep NH, Ward JM, Robertson G, Cohen-Gonsaud M, Henderson B, Cell Mol Life Sci, 2006

• Wake up! Peptidoglycan lysis and bacterial non-growth states

  Keep NH, Ward JM, Cohen-Gonsaud M, Henderson B, Trends Microbiol, 2006

2005

• The structure of a resuscitation-promoting factor domain from Mycobacterium tuberculosis shows homology to lysozymes

  Cohen-Gonsaud M, Barthe P, Bagneris C, Henderson B, Ward J, Roumestand C, Keep NH, Nat Struct Mol Biol, 2005

• Ligand-induced fit in mycobacterial MabA: the sequence-specific C-terminus locks the conformational change

  Cohen-Gonsaud M, Ducasse-Cabanot S, Quemard A, Labesse G, Proteins, 2005

2004

• Design of an amphipatic a-helical hairpin peptide

  Barthe P, Cohen-Gonsaud M, Aldrian-Herrada G, Chavanieu A, Labesse G, Roumestand C, Comptes Rendus Chimie, 2004

• (1)H, (15)N, and (13)C chemical shift assignments of the resuscitation promoting factor domain of Rv1009 from Mycobacterium tuberculosis

  Cohen-Gonsaud M, Barthe P, Pommier F, Harris R, Driscoll PC, Keep NH, Roumestand C, J Biomol NMR, 2004

• From molecular modelling to drug design

  Cohen-Gonsaud M, Catherinot V, Labesse G, Douguet D, Nucleid Acids and Molecular Biology, Vol 15, Practical Bioinformatics, Ed. by J.M. Bujnicki (2004) Springer-Verlag, 2004

• Resuscitation-promoting factors possess a lysozyme-like domain

  Cohen-Gonsaud M, Keep NH, Davies AP, Ward J, Henderson B, Labesse G, Trends in Biochemical Sciences, 2004

• In vitro inhibition of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein reductase MabA by isoniazid

  Ducasse-Cabanot S, Cohen-Gonsaud M, Marrakchi H, Nguyen M, Zerbib D, Bernadou J, Daffe M, Labesse G, Quemard A, Antimicrob Agents Chemother, 2004

• Heptahelical domain of metabotropic glutamate receptor 5 behaves like rhodopsin-like receptors

  Goudet C, Gaven F, Kniazeff J, Vol C, Liu J, Cohen-Gonsaud M, Acher F, Prezeau L, Pin JP, Proc Natl Acad Sci U S A, 2004

2003

• Use of the Protein MABA (FABG1) of MYCOBACTERIUM TUBERCULOSIS for designing and screening antibiotics

  Quemard A, Labesse G, Daffe M, Ducasse S, Cohen-Gonsaud M, Douguet D, Marrakchi H, , 2003

2002

• Crystal structure of MabA from Mycobacterium tuberculosis, a reductase involved in long-chain fatty acid biosynthesis

  Cohen-Gonsaud M, Ducasse S, Hoh F, Zerbib D, Labesse G, Quemard A, J Mol Biol, 2002