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CNRS Chaire Junior in cryo-electron microscopy
CALL FOR APPLICATIONS
CNRS CHAIRE JUNIOR in CRYO-ELECTRON MYCROSCOPY
The CBS is offering a group leader position in cell structural biology for a specialist in cryo-electron microscopy, cryo-tomography and correlative approaches.
This recruitment is made in the context of a tenure track position program named "Chaire Junior", supported by the CNRS. The contract is for a 5 years period and comes with a starting package of 575 k€. The gross annual salary is between 54600 to 57800 €, depending on professional experience.
For more information about the scientific environment and the recruitment process, please contact the CBS director, Pierre Emmanuel Milhiet (This email address is being protected from spambots. You need JavaScript enabled to view it.). Applications should be sent to him via email including CV, list of publications, names of 3 referees and motivation letter.
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PhD and PostDoc positions in molecular modeling of cellular condensates at CBS Montpellier (France)
CALL FOR APPLICATIONS
PhD and POSTDOCTORAL POSITIONS
AT CENTER FOR STRUCTURAL BIOLOGY (CBS)
IN MONTPELLIER, FRANCEA 3-year PhD fellowship and a 2-year postdoctoral position are available in our team at the CBS Montpellier (France) starting from autumn 2022. The positions are funded by the French National research Agency (ANR) within the BioTop (PhD) and Prospero (PostDoc) projects.
Both these collaborative projects aim at combining a variety of experimental techniques in biophysics and molecular/cellular biology with theoretical modelling for characterizing the functional, structural and mechanical properties of cellular condensates. Biomolecular condensates arising from the phase separation of proteins and/or nucleic acids are presently recognized to play a key role in organizing cellular environment and they are attracting a huge and ever-increasing attention in disparate fields
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2 Years Postdoctoral Position at Centre for Structural Biology (CBS) in Montpellier, France (2)
CALL FOR APPLICATIONS
POSTDOCTORAL POSITION
2 YEARS POSTDOCTORAL POSITION AT CENTER FOR STRUCTURAL BIOLOGY (CBS) IN
MONTPELLIER, FRANCE
Dr. Luca Costa
Integrative Biophysics of Membranes (IBM) TeamBiophysics and Bioengineering Department
https://integrativebiophysicsofmembranes.wordpress.com/
https://twitter.com/MembranesBiophySCIENTIFIC PROJECT AND JOB DESCRIPTION:
ELF3 plant proteins have the ability to undergo phase-change in response to environmental signals, such as temperature, enabling these proteins to act as developmental switches1. Phase-change occurs through dynamic compartmentalization into biomolecular condensates during the formation of Liquid-Liquid Phase Separation (LLPS) droplets. Their structure and the associated dynamics are usually assessed by Fluorescence Correlation Spectroscopy (FCS), FRAP or SAXS. However, they are
still poorly understood at the molecular level because nanometer-resolved images of the condensates are very challenging to obtain by means of conventional microscopy methods.Our goal is to study the structure and the associated dynamics of LLPS condensates with high spatial-temporal resolution by High-Speed Atomic Force Microscopy (HS-AFM), FCS and Fluorescence Lifetime Imaging (FLIM). With its minimal invasiveness, HS-AFM will be employed to catch single proteins diffusing at the LLPS interface, enabling the characterization of the intermolecular interactions. Results will be correlated with X-Ray (SAXS) and Electron Microscopy (EM) structural
data, as well as with theoretical models and simulations performed by our collaborators.more information here
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Internships
The CBS welcomes each year many interns of all levels, from high school to post-doctorate. Applications (CV and cover letter) should be sent directly to researchers from CBS teams.
PhD students are recruited through the CBS2 Doctoral School.
The PhD projects proposed by the CBS researchers can be viewed here.