Two folds, many faces: The Magnaporthe oryzae MAX effector AVR-Pia targets novel rice HMA domain-containing proteins
Friday, August 28, 2026
Two folds, many faces: The Magnaporthe oryzae MAX effector AVR-Pia targets novel rice HMA domain-containing proteins Rice blast, caused by the...
Science-Art film project : Resonances
Tuesday, June 16, 2026
Inserm has launched a new « science & art » film project titled “Résonances”, produced by Exaltia and freely available on YouTube:...
CNRS Year of Engineering
Monday, May 18, 2026
As part of the CNRS Year of Engineering, the CBS teams welcomed an STL Biotechnology class from Lycée Jean Mermoz (Montpellier) for two half-days....
Anjelica Kucinic awarded best poster at FNANO 2026
Wednesday, April 01, 2026
Anjelica, a postdoctoral researcher on Gaëtan Bellot team, presented her work at the 23rd annual Foundations of Nanoscience (FNANO) conference in...
Registrations are now open for ESAB 2026 Conference, June 16-19 2026, Montpellier
Thursday, January 08, 2026
Registrations are now open for ESAB 2026 Conference, June 16-19 2026, Montpellier CBS researchers are actively involved in organizing the 2nd ESAB...
BSI – Bordeaux 2025
Friday, December 19, 2025
The CBS was well represented during BSI 2025 , with 15 students, engineers, and researchers traveling to Bordeaux. Congratulations to Manon Mallet,...
ESAB 2026 Conference, June 16-19 2026
Friday, October 03, 2025
CBS researchers are actively involved in organizing the 2nd ESAB (European South Atlantic Biophysics) conference, which will be held from June 17 to...
Dévoilement du projet d’extension du CBS - 19/09/2025
Monday, September 15, 2025
Le 19 septembre 2025 à 14h30, l’Inserm donne le coup d’envoi officiel des travaux d’extension du Centre de Biologie Structurale (CBS), au coeur du...
Synonymous codons do not influence the amino-acid backbone conformation
Tuesday, June 17, 2025
The correlation between synonymous codon usage and secondary structure in translated proteins has been widely demonstrated and plays a capital role...
Pierre-Emmanuel Milhiet received into the Order of Academic Palms
Tuesday, May 27, 2025
Congratulations to Pierre-Emmanuel Milhiet, former Director of the CBS and Director of the Biology-Health Pole at the University of Montpellier,...
Mirror doctoral project: Designing remote-accessible bioelectronic cell systems for autonomous biomedical solutions
Friday, April 11, 2025
Doctoral project 1 : "Engineering and assembly of biohybrids for signal transduction integrating cellular biosensors with functional biopolymers"...
Exploring RNA destabilization mechanisms in biomolecular condensates through atomistic simulations
Friday, April 11, 2025
The complex and crowded cellular environment profoundly influences the structural properties and functions of biomolecules, including RNAs. In...
Join the qbio Master's Program [Quantitative Biology: Molecular Mechanisms of Living Systems (parcours IDIL)] Q&A Session on Monday, February 10!
Tuesday, February 04, 2025
The qbio Master's program [ Quantitative Biology: Molecular Mechanisms of Living Systems (parcours IDIL)] at the University of Montpellier is an...
Le Centre de Biologie Structurale (CBS) de Montpellier s’engage à accueillir 6 stagiaires de seconde générale et technologique, du 16 au 27 juin 2025
Thursday, January 30, 2025
STAGES de SECONDE Le Centre de Biologie Structurale (CBS) de Montpellier s’engage à accueillir 6 stagiaires de seconde générale et technologique, du...
Ashley Nord awarded with the bronze medal of CNRS
Tuesday, November 19, 2024
Congratulations to Ashley Nord, who recieved on Friday November 15th the Bronze medal 2024 from CNRS https://www.inp.cnrs.fr/fr/personne/ashley-nord
When cryo-electron tomography uncovers the in cellulo structural organization of the Chikungunya virus replication complex
Tuesday, July 02, 2024
When cryo-electron tomography and sub-tomogram averaging techniques uncover the in cellulo structural organization of the Chikungunya virus...
2D DNA-origami assembly for Cryo-EM Applications
Tuesday, May 14, 2024
We propose a self-assembled DNA origami honeycomb 2D-lattice as a molecular imaging scaffold for Cryo-Electron Microscopy (Cryo-EM). The thin,...
The “Impulscience” prize awarded to Ashley Nord
Wednesday, November 22, 2023
The Impulscience® program aims to reward and support excellent researchers in France, and to strengthen the attractiveness of France as a place of...
Multi-scale dynamic imaging reveals that cooperative motility behaviors promote efficient predation in bacteria
Thursday, October 05, 2023
Overlay of Myxococcus xanthus bacteria trajectories during the invasion of an Escherichia coli colony. Publication link: Rombouts, S., Mas, A., Le...
Phosphorylation motif dictates GPCR C-terminal domain conformation and arrestin interaction
Friday, September 08, 2023
Link to publication: https://www.sciencedirect.com/science/article/abs/pii/S0969212623002897?dgcid=author The signaling pathways of...
Combining mechanical and superresolution measurements to reveal the plasticity of the Nuclear Pore Complexes
Wednesday, March 29, 2023
Nuclear pore complexes (NPCs) are the only gateways between the nucleus and cytoplasm in eukaryotic cells, facilitating the transport of selected...
The structure of pathogenic huntingtin exon-1 defines the bases of its aggregation propensity
Friday, March 10, 2023
Link to publication: https://www.nature.com/articles/s41594-023-00920-0 Huntington’s Disease (HD) is a deadly neurodegenerative disorder caused by...
Structure of the dioxin receptor (AHR) revealed by cryo-electron microscopy
Tuesday, November 22, 2022
Living organisms have evolved protein sensors that help them adapt to their environment. The aromatic hydrocarbon receptor (AHR) is an emblematic...
Get out of here, let me get on it ! The G protein and the beta-arrestiin
Monday, October 10, 2022
Arginine-vasopressin (AVP) is known as the antidiuretic hormone, and it regulates a vital function of our body: water homeostasis. It plays a role...
Original structure and regulation by acetylation of human NADK2
Friday, September 30, 2022
NAD+ kinases (NADKs) are metabolite kinases that phosphorylate NAD+ molecules to make NADP+, a limiting substrate for the generation of reducing...
DNA origami to explore cell mechanotransduction
Thursday, September 01, 2022
How cells respond to mechanical forces by converting them into biological signals underlie crucial cellular processes. Our understanding of...
The C-terminal domains of GPCR are disordered with transient secondary structures
Tuesday, July 05, 2022
Arrestin-dependent pathways are a central component of G protein-coupled receptor (GPCR) signaling. This pathway is activated after the...
Dynamic stiffening of the flagellar hook
Monday, June 13, 2022
For many bacteria, motility stems from one or more flagella, each rotated by the bacterial flagellar motor, a powerful rotary molecular machine. The...
Cryo-EM structure of the V2R:AVP:Gs complex
Friday, June 11, 2021
The cryo-EM structure of the antidiuretic hormone arginine-vasopressin V2 receptor signaling complex Arginine-vasopressin (AVP) is known as the...
Phd Postdoc Day - 2021 July 5th
Tuesday, June 08, 2021
The first CBS PhD/postdoc meeting will be held on Monday, the 5th of July via Zoom ! This day will gather all non-permanent young researchers from...
Quantifying ribosome traffic from profiling data
Thursday, January 28, 2021
A non-equilibrium analysis model was developed for inferring the relative rates of translation initiation and elongation rates from ribosome...
Programming history-dependent logic in cellular populations
Tuesday, January 26, 2021
Genetic programs operating in a history-dependent fashion are ubiquitous in nature and govern sophisticated processes such as development and...
How chemical pollutants can become more harmful when combined
Monday, January 25, 2021
So-called endocrine disruptors — environmental pollutants that can cause reproductive, metabolic, or neurological disorders — target the pregnane X...
Speech can propagate pathogens
Friday, October 09, 2020
Speech is a potent route for viral transmission in the COVID-19 pandemic. Informed mitigation strategies are difficult to develop since no...
Important implication of intrinsically disordered protein in signaling pathways
Friday, July 17, 2020
Cellular signaling machinery is involved in major physiological processes and therefore in a large number of diseases. However, full understanding...
ATP-driven separation of liquid phase condensates in bacteria
Wednesday, July 15, 2020
Liquid-liquid phase separated (LLPS) states are key to compartmentalise components in the absence of membranes, however it is unclear whether LLPS...
Study on cis-regulatory chromatin loops
Wednesday, July 08, 2020
Cis-regulatory chromatin loops arise before TADs and gene activation, and are independent of cell fate during development Sergio Martin Espinola,...
Transcription and chromosome observation in single cells with Hi-M
Wednesday, July 08, 2020
Direct and simultaneous observation of transcription and chromosome architecture in single cells with Hi-M Andrés M. Cardozo Gizzi, Sergio M....
Engineering ‘Plug-and-Play’ Cell-Free Biosensors
Tuesday, July 07, 2020
Cell-free protein synthesis represents a promising avenue for developing next-generation diagnostics. Researchers at the Center for Structural...
Absence of proline cis-conformation in poly-proline tracts
Thursday, July 02, 2020
The study of prolines within proteins has been traditionally a challenge, especially in repetitions (poly-proline). By combining site-specific...
COVID generation: workshop in an elementary school
Wednesday, July 01, 2020
What is a microbe? What are the differences between a bacteria and a virus? How does soap protect against viruses? Animated debates, experiences......
High-Res Photonic Force Microscopy Based on Sharp Nanofabricated Tips
Friday, June 26, 2020
The photonic force microscope (PhFM) is better suited than the atomic force microscope (AFM) to the observation of soft tissues, in particular...
CBS Lifetime Seminar Series
Monday, September 23, 2019
This year, the Centre of Structural Biochemistry is organizing a series of seminars on topics related to the LifeTime Initiative . If you want to...
Le CBS participe à la Fête de la Science
Sunday, September 08, 2019
Le Cente de Biochimie Structurale ouvre ses portes et organise plusieurs évenements pour fêter les 80 ans du CNRS à l'occasion de l'édition 2019 de...
Mechanism of host-pathogen recognition
Monday, November 12, 2018
Rice, like other plants, has immune receptors represented largely by the family of NLR proteins. Some of these proteins have an integrated decoy...
A new mecanism for transcription initiation in M. Tuberculosis
Monday, May 28, 2018
In bacteria, the sigma subunit of RNA polymerase controls promoter recognition and initiation of RNA synthesis. Using Förster energy transfer...
Une nouvelle méthode ouvre la voie à l’étude des protéines à séquence répétée
Tuesday, April 24, 2018
Certaines pathologies – c'est notamment le cas de la maladie de Huntington - sont causées par des protéines présentant un nombre anormalement élevé...
25th anniversary of the CBS
Tuesday, March 20, 2018
The CBS organizes a special event to celebrate its twenty-fifth anniversary on May 24 and 25, 2018 . The research that has been conducted there for...
Teaching bacteria to recognize new molecules
Tuesday, March 20, 2018
Microbes can be engineered for different applications in our daily life, such as microbiome therapeutics, diagnosis of disease, or environmental...
Biochemical approach to understand Huntington's disease and poly-glutamine-related pathologies
Monday, March 05, 2018
Huntington's Disease (HD) is a hereditary neurodegenerative disorder that is characterized by involuntary movements, general motor impairment,...
Rare yet specific interactions shape the 3D folding of chromatin
Tuesday, January 16, 2018
The organization of DNA in the three-dimensional space of the cell nucleus determines the regulation of most cellular activities. In recent years, a...
Catch-bond and mechanosensing of the bacterial flagellar motor
Monday, December 11, 2017
The bacterial flagellar motor (BFM) is the rotary motor that rotates each bacterial flagellum, powering the swimming and swarming of many motile...
Impact of fluorescent protein fusions on the bacterial flagellar motor
Thursday, November 02, 2017
Fluorescent fusion proteins open a direct and unique window onto protein function. However, they also introduce the risk of perturbation of the...
3D supramolecular assemblies from 2D super-resolution microscopy images
Thursday, October 05, 2017
HOW TO GET 3D RECONSTRUCTION OF SUPRAMOLECULAR ASSEMBLIES FROM 2D SUPER-RESOLUTION LIGHT MICROSCOPY IMAGES? Super-resolution microscopies enable...
Monitoring protein folding through high pressure NMR spectroscopy
Wednesday, June 14, 2017
Everything you always wanted to know on the use of High-Pressure NMR to study Protein Folding (but were afraid to ask). "Monitoring protein folding...
Host-pathogen recognition by the integrated decoy model
Thursday, January 19, 2017
NLR multidomain proteins largely mediate the immune response in plants. These immune receptors are the key elements in the recognition of the...
Unravelling bacterial motility
Thursday, October 20, 2016
During its evolution, the gram-negative bacteria Myxococcus xanthus has developed an original property : the ability to move on surfaces in the...
DNA segregation super-resolved
Wednesday, October 19, 2016
To ensure proper growth, bacterial genome must be faithfully segregated so that each daughter cell, resulting from cellular division, inherits an...
Vanessa Delfosse receives the "Grandes avancées françaises en biologie" prize
Thursday, April 28, 2016
The french Academy of sciences rewards young researchers for their contribution to major scientific advances in biology. Links: Video Académie des...
Tournants et bifurcations, acteurs de la vasoocclusion drépanocytaire?
Wednesday, October 21, 2015
La drépanocytose affecte plus de 50 millions de personnes dans le monde et se caractérise par des crises douloureuses de vasoocclusion dont la...
Insights into the "cocktail effect" of endocrine disruptors
Monday, September 07, 2015
Chemicals which taken in isolation are safe for humans may become harmful when mixed . The team of William Bourguet in Structural Biochemistry...
New Structure of a Protein Modulating Bacterial Gene Silencing
Wednesday, September 02, 2015
Antibiotic resistance and the appearance of new virulent bacterial strains constitute a major threat to human health. The problem is aggravated by...
Activation Mechanism of the Morphine Receptor Revealed
Monday, August 31, 2015
A close collaboration between the team of Sebastien Granier (IGF) in Montpellier, Hélène Déméné (CBS, team "NMR, Structure, Dynamics and Function of...
Programming bacteria to detect disease
Thursday, May 28, 2015
Bacteria have a bad reputation and are often seen as enemies causing many diseases such as tuberculosis and cholera. However, bacteria can also be...
Variable Effect of Kinase Inhibitors on Breast Cancer Cell Lines
Tuesday, April 21, 2015
Breast tumors belonging to the triple negative subgroup (TN) (no estrogen, no progesterone and no ERBB2 receptors expressed) are the most aggressive...
Two CBS students receive prizes for youg researchers
Wednesday, April 01, 2015
Congratulations to Patrice Rassam (PhD student 2008-2012 in the team of P.E. Milhiet) who has just been selected to receive the "Prix du Jeune...
