Centre de Biologie Structurale

News

Seminars

12 Jun

LLPS seminar 12 Jun 2023 11:00 AM to 12:00 PM
14 Jun

CE CBS 14 Jun 2023 09:30 AM to 10:30 AM
15 Jun

CBS Talk, Claire Cargemel (CBS, Team1) 15 Jun 2023 11:00 AM to 12:00 PM
Host: Nathalie Declerck

12 Jun - 15 Jun
19 Jun - 22 Jun
22 Jun - 26 Jun
26 Jun - 06 Jul
07 Jul - 13 Jul
18 Jul - 24 Jul
01 Aug - 04 Aug

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Latest publications

Multi-site-specific isotopic labeling accelerates high-resolution structural investigations of pathogenic huntingtin exon-1
Elena-Real CA, Urbanek A, Lund XL, Morato A, Sagar A, Fournet A, Estana A, Bellande T, Allemand F, Cortes J, Sibille N, Melki R, Bernado P, Structure, 2023
Pharmacological activation of PIEZO1 in human red blood cells prevents Plasmodium falciparum invasion
Lohia R, Allegrini B, Berry L, Guizouarn H, Cerdan R, Abkarian M, Douguet D, Honore E, Wengelnik K, Cell Mol Life Sci, 2023
Assembly mechanism and cryoEM structure of RecA recombination nucleofilaments from Streptococcus pneumoniae
Hertzog M, Perry TN, Dupaigne P, Serres S, Morales V, Soulet AL, Bell JC, Margeat E, Kowalczykowski SC, Le Cam E, Fronzes R, Polard P, Nucleic Acids Res, 2023
Small-Molecule Cyclophilin Inhibitors Potently Reduce Platelet Procoagulant Activity
Van Bael J, Vandenbulcke A, Ahmed-Belkacem A, Guichou JF, Pawlotsky JM, Samyn J, Barendrecht AD, Maas C, De Meyer SF, Vanhoorelbeke K, Tersteeg C, Int J Mol Sci, 2023
A Tripartite Complex HIV-1 Tat-Cyclophilin A-Capsid Protein Enables Tat Encapsidation That Is Required for HIV-1 Infectivity
Schatz M, Marty L, Ounadjela C, Tong PBV, Cardace I, Mettling C, Milhiet PE, Costa L, Godefroy C, Pugniere M, Guichou JF, Mesnard JM, Blaise M, Beaumelle B, J Virol, 2023
A Mycobacterium tuberculosis Effector Targets Mitochondrion, Controls Energy Metabolism, and Limits Cytochrome cExit
Martin M, deVisch A, Boudehen YM, Barthe P, Gutierrez C, Turapov O, Aydogan T, Heriaud L, Gracy J, Neyrolles O, Mukamolova GV, Letourneur F, Cohen-Gonsaud M, Microbiol Spectr, 2023
Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair
Alghoul E, Paloni M, Takedachi A, Urbach S, Barducci A, Gaillard PH, Basbous J, Constantinou A, Mol Cell, 2023
Reliability and accuracy of single-molecule FRET studies for characterization of structural dynamics and distances in proteins
Agam G, Gebhardt C, Popara M, Machtel R, Folz J, Ambrose B, Chamachi N, Chung SY, Craggs TD, de Boer M, Grohmann D, Ha T, Hartmann A, Hendrix J, Hirschfeld V, Hubner CG, Hugel T, Kammerer D, Kang HS, Kapanidis AN, Krainer G, Kramm K, Lemke EA, Lerner E, Margeat E, Martens K, Michaelis J, Mitra J, Moya Munoz GG, Quast RB, Robb NC, Sattler M, Schlierf M, Schneider J, Schroeder T, Sefer A, Tan PS, Thurn J, Tinnefeld P, van Noort J, Weiss S, Wendler N, Zijlstra N, Barth A, Seidel CAM, Lamb DC, Cordes T, Nat Methods, 2023
Structure and mechanics of the human nuclear pore complex basket using correlative AFM-fluorescence superresolution microscopy
Vial A, Costa L, Dosset P, Rosso P, Boutieres G, Faklaris O, Haschke H, Milhiet PE, Doucet CM, Nanoscale, 2023
WASCO: A Wasserstein-based statistical tool to compare conformational ensembles of intrinsically disordered proteins
Gonzalez-Delgado J, Sagar A, Zanon C, Lindorff-Larsen K, Bernado P, Neuvial P, Cortes J, J Mol Biol, 2023
Retinoic Acid and Retinoid X Receptors
Schubert M, Germain P, Cells, 2023
Contributions of 3D chromatin structure to cell-type-specific gene regulation
Schaeffer M, Nollmann M, Curr Opin Genet Dev, 2023
The structure of pathogenic huntingtin exon 1 defines the bases of its aggregation propensity
Elena-Real CA, Sagar A, Urbanek A, Popovic M, Morato A, Estana A, Fournet A, Doucet C, Lund XL, Shi ZD, Costa L, Thureau A, Allemand F, Swenson RE, Milhiet PE, Crehuet R, Barducci A, Cortes J, Sinnaeve D, Sibille N, Bernado P, Nat Struct Mol Biol, 2023
2,4-Di-tert-butylphenol Induces Adipogenesis in Human Mesenchymal Stem Cells by Activating Retinoid X Receptors
Ren XM, Chang RC, Huang Y, Amorim Amato A, Carivenc C, Grimaldi M, Kuo Y, Balaguer P, Bourguet W, Blumberg B, Endocrinology, 2023
Unmasking of the von Willebrand A-domain surface adhesin CglB at bacterial focal adhesions mediates myxobacterial gliding motility
Islam ST, Jolivet NY, Cuzin C, Belgrave AM, My L, Fleuchot B, Faure LM, Mahanta U, Kezzo AA, Saidi F, Sharma G, Fiche JB, Bratton BP, Herrou J, Nollmann M, Shaevitz JW, Durand E, Mignot T, Sci Adv, 2023
An optimized electrotransformation protocol for Lactobacillus jensenii
Fristot E, Bessede T, Camacho Rufino M, Mayonove P, Chang HJ, Zuniga A, Michon AL, Godreuil S, Bonnet J, Cambray G, PLoS One, 2023
Nucleation of Biomolecular Condensates from Finite-Sized Simulations
Li L, Paloni M, Finney AR, Barducci A, Salvalaglio M, J Phys Chem Lett, 2023
Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization
Morichaud Z, Trapani S, Vishwakarma RK, Chaloin L, Lionne C, Lai-Kee-Him J, Bron P, Brodolin K, Nat Commun, 2023
Structure-guided mutagenesis of the capsid protein indicates that a nanovirus requires assembled viral particles for systemic infection
Trapani S, Bhat EA, Yvon M, Lai-Kee-Him J, Hoh F, Vernerey MS, Pirolles E, Bonnamy M, Schoehn G, Zeddam JL, Blanc S, Bron P, PLoS Pathog, 2023
The Syp1/FCHo2 protein induces septin filament bundling through its intrinsically disordered domain
Ibanes S, El-Alaoui F, Lai-Kee-Him J, Cazevieille C, Hoh F, Lyonnais S, Bron P, Cipelletti L, Picas L, Piatti S, Cell Rep, 2022
Mechanical DNA Origami to Investigate Biological Systems
Mills A, Aissaoui N, Finkel J, Elezgaray J, Bellot G, Adv Biol (Weinh), 2022
Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria
Clement DA, Gelin M, Leseigneur C, Huteau V, Mondange L, Pons JL, Dussurget O, Lionne C, Labesse G, Pochet S, Eur J Med Chem, 2022
TOPOVIBL-REC114 interaction regulates meiotic DNA double-strand breaks
Nore A, Juarez-Martinez AB, Clement J, Brun C, Diagouraga B, Laroussi H, Grey C, Bourbon HM, Kadlec J, Robert T, de Massy B, Nat Commun, 2022
Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex
Gruszczyk J, Grandvuillemin L, Lai-Kee-Him J, Paloni M, Savva CG, Germain P, Grimaldi M, Boulahtouf A, Kwong HS, Bous J, Ancelin A, Bechara C, Barducci A, Balaguer P, Bourguet W, Nat Commun, 2022
The sequence context in poly-alanine regions: structure, function and conservation
Mier P, Elena-Real CA, Cortes J, Bernado P, Andrade-Navarro MA, Bioinformatics, 2022
Disentangling polydisperse biomolecular systems by Chemometrics decomposition of SAS data
Sagar A, Bernado P, Methods Enzymol, 2022
Statistical proofs of the interdependence between nearest neighbor effects on polypeptide backbone conformations
Gonzalez-Delgado J, Bernado P, Neuvial P, Cortes J, J Struct Biol, 2022
Computational Methods for the Design of Recombinase Logic Circuits with Adaptable Circuit Specifications
Zuniga A, Bonnet J, Guiziou S, Methods Mol Biol, 2022
eIF4G1 N-terminal intrinsically disordered domain is a multi-docking station for RNA, Pab1, Pub1, and self-assembly
Chaves-Arquero B, Martinez-Lumbreras S, Sibille N, Camero S, Bernado P, Jimenez M, Zorrilla S, Perez-Canadillas JM, Front Mol Biosci, 2022
Multiple parameters shape the 3D chromatin structure of single nuclei at the doc locus in Drosophila
Goetz M, Messina O, Espinola S, Fiche JB, Nollmann M, Nat Commun, 2022

View all publications

CBS Teams

Structure, Dynamics and Function of biomolecules by NMR

Christian Roumestand and Nathalie Declerck
Structure and function of highly flexible proteins

Pau Bernadó and Nathalie Sibille
Multi-scale structural biology

Patrick Bron
ABCIS

Gilles Labesse
Nuclear Receptors as Integrators of Endogenous and Environmental Signals

William Bourguet and Albane Le Maire
Multiscale Biomolecular Modeling

Alessandro Barducci
Mechanisms of DNA Segregation and Remodelling

Marcelo Nollmann
Physics and mechanics of biological systems

Manouk Abkarian and Francesco Pedaci
Integrative Biophysics of Membranes

Pierre-Emmanuel Milhiet and Emmanuel Margeat
Synthetic Biology

Jérôme Bonnet and Martin Cohen-Gonsaud
Multiscale Biomolecular Modeling

Alessandro Barducci
Chromosome structure and homologous recombination in meiosis

Thomas Robert
Functional and synthetic genomics

Guillaume Cambray
Structure and function of the aryl hydrocarbon receptor

Jakub Gruszczyk

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