Plateforme Intégrée de Biophysique et de Biologie Structurale


Crystallisation screening and crystallisation conditions optimization


Obtaining diffracting protein crystals which are required to obtain atomic-level structures via
X-ray diffraction techniques

The crystallization experiments are set up in 96 well sitting drop plates via nano-dispensing robot (50-100 nl/drop, Mosquito, STPLabtech). For initial screening we're using commercial screens and for crystallization optimization, commercial additifs and home made solution . The facility is equipped with an automated imaging system for protein crystallization (Rock Imager, Formulatrix).


Used plates: 96 well plates and 24 wells plates


Mosquito HTS (Stplabtech) nano dispensing

Dragongly (StpLabtech) crystallisation conditions optimization


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