Liste des publications

2024

• The structural landscape and diversity of Pyricularia oryzae MAX effectors revisited

  Lahfa M, Barthe P, deGuillen K, Cesari S, Raji M, Kroj T, Le Naour-Vernet M, Hoh F, Gladieux P, Roumestand C, Gracy J, Declerck N, Padilla A, PLoS Pathog, 2024

2023

• Structure, dynamics and transferability of the metal-dependent polyhistidine tetramerization motif TetrHis for single-chain Fv antibodies

  Healey RD, Couillaud L, Hoh F, Mouhand A, Fouillen A, Couvineau P, Granier S, Leyrat C, Commun Chem, 2023

• Structure-guided mutagenesis of the capsid protein indicates that a nanovirus requires assembled viral particles for systemic infection

  Trapani S, Bhat EA, Yvon M, Lai-Kee-Him J, Hoh F, Vernerey MS, Pirolles E, Bonnamy M, Schoehn G, Zeddam JL, Blanc S, Bron P, PLoS Pathog, 2023

2022

• The Syp1/FCHo2 protein induces septin filament bundling through its intrinsically disordered domain

  Ibanes S, El-Alaoui F, Lai-Kee-Him J, Cazevieille C, Hoh F, Lyonnais S, Bron P, Cipelletti L, Picas L, Piatti S, Cell Rep, 2022

• Unravelling the Adaptation Mechanisms to High Pressure in Proteins

  Calio A, Dubois C, Fontanay S, Koza MM, Hoh F, Roumestand C, Oger P, Peters J, Int J Mol Sci, 2022

• A flexible and original architecture of two unrelated zinc fingers underlies the role of the multitask P1 in RYMV spread

  Poignavent V, Hoh F, Terral G, Yang Y, Gillet FX, Kim JH, Allemand F, Lacombe E, Brugidou C, Cianferani S, Demene H, Vignols F, J Mol Biol, 2022

• Structural insights into recognition of chemokine receptors by Staphylococcus aureusleukotoxins

  Lambey P, Otun O, Cong X, Hoh F, Brunel L, Verdie P, Grison CM, Peysson F, Jeannot S, Durroux T, Bechara C, Granier S, Leyrat C, Elife, 2022

• Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations

  Nasrallah C, Cannone G, Briot J, Rottier K, Berizzi AE, Huang CY, Quast RB, Hoh F, Baneres JL, Malhaire F, Berto L, Dumazer A, Font-Ingles J, Gomez-Santacana X, Catena J, Kniazeff J, Goudet C, Llebaria A, Pin JP, Vinothkumar KR, Lebon G, Cell Rep, 2022

2018

• Structure of a human intramembrane ceramidase explains enzymatic dysfunction found in leukodystrophy

  Vasiliauskaite-Brooks I, Healey RD, Rochaix P, Saint-Paul J, Sounier R, Grison C, Waltrich-Augusto T, Fortier M, Hoh F, Saied EM, Arenz C, Basu S, Leyrat C, Granier S, Nat Commun, 2018

• Structural determinants of the catalytic mechanism of Plasmodium CCT, a key enzyme of malaria lipid biosynthesis

  Guca E, Nagy GN, Hajdu F, Marton L, Izrael R, Hoh F, Yang Y, Vial H, Vertessy BG, Guichou JF, Cerdan R, Sci Rep, 2018

2017

• C9/12-ribbon-like structure in hybrid peptides alternating alpha- and thiazole-based gamma-amino acids

  Bonnel C, Legrand B, Simon M, Martinez J, Bantignies JL, Kang YK, Wenger E, Hoh F, Masurier N, Maillard LT, Chemistry, 2017

• Structural insights into adiponectin receptors suggest ceramidase activity

  Vasiliauskaite-Brooks I, Sounier R, Rochaix P, Bellot G, Fortier M, Hoh F, De Colibus L, Bechara C, Saied EM, Arenz C, Leyrat C, Granier S, Nature, 2017

2015

• Combining `dry' co-crystallization and in situ diffraction to facilitate ligand screening by X-ray crystallography

  Gelin M, Delfosse V, Allemand F, Hoh F, Sallaz-Damaz Y, Pirocchi M, Bourguet W, Ferrer JL, Labesse G, Guichou JF, Acta Crystallogr D Biol Crystallogr, 2015

2014

• Structural and Biochemical Characterization of the Cop9 Signalosome CSN5/CSN6 Heterodimer

  Birol M, Enchev RI, Padilla A, Stengel F, Aebersold R, Betzi S, Yang Y, Hoh F, Peter M, Dumas C, Echalier A, PLoS ONE, 2014

• Aedesin: Structure and Antimicrobial Activity against Multidrug Resistant Bacterial Strains

  Godreuil S, Leban N, Padilla A, Hamel R, Luplertlop N, Chauffour A, Vittecoq M, Hoh F, Thomas F, Sougakoff W, Lionne C, Yssel H, Misse D, PLoS ONE, 2014

2013

• Insights into the regulation of the human COP9 signalosome catalytic subunit, CSN5/Jab1

  Echalier A, Pan Y, Birol M, Tavernier N, Pintard L, Hoh F, Ebel C, Galophe N, Claret FX, Dumas C, Proc Natl Acad Sci USA, 2013

• Fragment-Based Identification of a Locus in the Sec7 Domain of Arno for the Design of Protein-Protein Interaction Inhibitors

  Rouhana J, Hoh F, Estaran S, Henriquet C, Boublik Y, Kerkour A, Trouillard R, Martinez J, Pugniere M, Padilla A, Chavanieu A, J Med Chem, 2013

2012

• An integrated chemical biology approach provides insight into cdk2 functional redundancy and inhibitor sensitivity

  Echalier A, Cot E, Camasses A, Hodimont E, Hoh F, Jay P, Sheinerman F, Krasinska L, Fisher D, Chem Biol, 2012

2011

• In-plate protein crystallization, in situ ligand soaking and X-ray diffraction

  le Maire A, Gelin M, Pochet S, Hoh F, Pirocchi M, Guichou JF, Ferrer JL, Labesse G, Acta Crystallogr D Biol Crystallogr, 2011

2010

• Structural insights into the molecular mechanisms of cauliflower mosaic virus transmission by its insect vector

  Hoh F, Uzest M, Drucker M, Plisson-Chastang C, Bron P, Blanc S, Dumas C, J Virol, 2010

2009

• Removing the invariant salt bridge of parvalbumin increases flexibility in the AB-loop structure

  Hoh F, Cave A, Strub MP, Baneres JL, Padilla A, Acta Crystallogr D Biol Crystallogr, 2009

• Structure of Debaryomyces castellii CBS 2923 phytase

  Ragon M, Hoh F, Aumelas A, Chiche L, Moulin G, Boze H, Acta Crystallogr Sect F Struct Biol Cryst Commun, 2009

2007

• Structure of PlcR: Insights into virulence regulation and evolution of quorum sensing in Gram-positive bacteria

  Declerck N, Bouillaut L, Chaix D, Rugani N, Slamti L, Hoh F, Lereclus D, Arold ST, Proc Natl Acad Sci U S A, 2007

• Role of Asn(2) and Glu(7) residues in the oxidative folding and on the conformation of the N-terminal loop of apamin

  Le-Nguyen D, Chiche L, Hoh F, Martin-Eauclaire MF, Dumas C, Nishi Y, Kobayashi Y, Aumelas A, Biopolymers, 2007

2005

• Structure of a liganded type 2 non-specific lipid-transfer protein from wheat and the molecular basis of lipid binding

  Hoh F, Pons JL, Gautier MF, de Lamotte F, Dumas C, Acta Crystallogr D Biol Crystallogr, 2005

2004

• High-resolution X-ray structure of the unexpectedly stable dimer of the [Lys(-2)-Arg(-1)-des(17-21)]endothelin-1 peptide

  Hoh F, Cerdan R, Kaas Q, Nishi Y, Chiche L, Kubo S, Chino N, Kobayashi Y, Dumas C, Aumelas A, Biochemistry, 2004

2003

• 1H, (15)N and (13)C chemical shift assignments of the Pleckstrin Homology domain of the Human Protein Kinase B (Pkb/Akt)

  Auguin D, Barthe P, Auge-Senegas MT, Hoh F, Noguchi M, Roumestand C, J. Biomol. NMR, 2003

• Selenomethionine and selenocysteine double labeling strategy for crystallographic phasing

  Strub MP, Hoh F, Sanchez JF, Strub JM, Bock A, Aumelas A, Dumas C, Structure (Camb), 2003

2002

• Crystal structure of MabA from Mycobacterium tuberculosis, a reductase involved in long-chain fatty acid biosynthesis

  Cohen-Gonsaud M, Ducasse S, Hoh F, Zerbib D, Labesse G, Quemard A, J Mol Biol, 2002

• Combining selenomethionine and selenocysteine protein labelling for MAD experiment: a promising method for the structural genomics

  Hoh F, Strub, M.P., Sanchez, J.F., Strub, J.M., Bock, A., Aumelas A., Dumas, C., Acta Crystallographica Section A, 2002

• Identification of Akt association and oligomerization domains of the Akt kinase coactivator TCL1.

  Kunstle G, Laine J, Pierron G, Kagami SS, Nakajima H, Hoh F, Roumestand C, Stern MH, M. N, Mol Cell Biol, 2002

• Structure of the cathelicidin motif of protegrin-3 precursor: structural insights into the activation mechanism of an antimicrobial protein

  Sanchez JF, Hoh F, Strub MP, Aumelas A, Dumas C, Structure, 2002

• Crystallization and preliminary X-ray crystallographic analysis of human Geminin coiled-coil domain

  Thepaut M, Hoh F, Dumas C, Calas B, Strub MP, Padilla A, Biochim Biophys Acta, 2002

2001

• Expression, purification, crystallization and preliminary X-ray analysis of the cathelicidin motif of the protegrin-3 precursor

  Sanchez JF, Hoh F, Strub MP, Strub JM, Van Dorsselaer A, Lehrer R, Ganz T, Chavanieu A, Calas B, Dumas C, Aumelas A, Acta Crystallogr D Biol Crystallogr, 2001

2000

• Characterization and molecular basis of the oligomeric structure of HIV- 1 nef protein

  Arold S, Hoh F, Domergue S, Birck C, Delsuc MA, Jullien M, Dumas C, Protein Sci, 2000

1999

• RNA recognition by transcriptional antiterminators of the BglG/SacY family: functional and structural comparison of the CAT domain from SacY and LicT

  Declerck N, Vincent F, Hoh F, Aymerich S, van Tilbeurgh H, J Mol Biol, 1999

1998

• RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef

  Arold S, O'Brien R, Franken P, Strub MP, Hoh F, Dumas C, Ladbury JE, Biochemistry, 1998

• The preliminary solution structure of human p8MTCP1, a protein encoded by the putative MTCP1 oncogene

  Barthe P, Guignard L, Yang YS, Chiche L, Strub MP, Hoh F, Stern MH, Roumestand C, J. Chim. Phys., 1998

• Crystal structure of p14TCL1, an oncogene product involved in T-cell prolymphocytic leukemia, reveals a novel beta-barrel topology

  Hoh F, Yang YS, Guignard L, Padilla A, Stern MH, Lhoste JM, van Tilbeurgh H, Structure, 1998

• Solution structure of the recombinant human oncoprotein p13MTCP1

  Yang YS, Guignard L, Padilla A, Hoh F, Strub MP, Stern MH, Lhoste JM, Roumestand C, J Biomol NMR, 1998

1997

• The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling

  Arold S, Franken P, Strub MP, Hoh F, Benichou S, Benarous R, Dumas C, Structure, 1997

• Solution structure of human p8MTCP1, a cysteine-rich protein encoded by the MTCP1 oncogene, reveals a new alpha-helical assembly motif

  Barthe P, Yang YS, Chiche L, Hoh F, Strub MP, Guignard L, Soulier J, Stern MH, van Tilbeurgh H, Lhoste JM, Roumestand C, J. Mol. Biol., 1997

• HIV-1 Nef protein: purification, crystallizations, and preliminary X-ray diffraction studies

  Franken P, Arold S, Padilla A, Bodeus M, Hoh F, Strub MP, Boyer M, Jullien M, Benarous R, Dumas C, Protein Sci, 1997

1996

• Bacterial siderophores: structure elucidation, and 1H, 13C and 15N two-dimensional NMR assignments of azoverdin and related siderophores synthesized by Azomonas macrocytogenes ATCC 12334

  Bernardini J-J, Linget-Morice C, Hoh F, Collinson SK, Kyslik P, Page WJ, Dell A, Abdallah MA, BioMetals, 1996