Centre de Biologie Structurale

News

Seminars

04 Dec

Biophysics Meeting: Olivier 04 Dec 2023 11:00 AM to 12:00 PM
05 Dec

Comité de direction CBS 05 Dec 2023 02:00 PM to 04:00 PM
06 Dec

PHD. THESIS defense "Mounia LAHFA" 06 Dec 2023 02:00 PM to 04:00 PM
Titre:

"Diversité structurale des effecteurs MAX"

Title:

"Structural diversity of MAX effectors"

04 Dec - 06 Dec
08 Dec - 11 Dec
12 Dec - 15 Dec
18 Dec - 21 Dec
22 Dec - 29 Dec
08 Jan - 09 Jan
11 Jan - 12 Jan

‹ ›

Latest publications

The genome of a bunyavirus cannot be defined at the level of the viral particle but only at the scale of the viral population
Yvon M, German TL, Ullman DE, Dasgupta R, Parker MH, Ben-Mahmoud S, Verdin E, Gognalons P, Ancelin A, Lai Kee Him J, Girard J, Vernerey MS, Fernandez E, Filloux D, Roumagnac P, Bron P, Michalakis Y, Blanc S, Proc Natl Acad Sci U S A, 2023
A single-domain intrabody targeting the follicle-stimulating hormone receptor impacts FSH-induced G protein-dependent signalling
Raynaud P, Jugnarain V, Vaugrente O, Vallet A, Boulo T, Gauthier C, Inoue A, Sibille N, Gauthier C, Jean-Alphonse F, Reiter E, Crepieux P, Bruneau G, FEBS Lett, 2023
Structure-function relationships in protein homorepeats
Elena-Real CA, Mier P, Sibille N, Andrade-Navarro MA, Bernado P, Curr Opin Struct Biol, 2023
PED in 2024: improving the community deposition of structural ensembles for intrinsically disordered proteins
Ghafouri H, Lazar T, Del Conte A, Tenorio Ku LG, Tompa P, Tosatto SCE, Monzon AM, Aspromonte MC, Bernado P, Chaves-Arquero B, Chemes LB, Clementel D, Cordeiro TN, Elena-Real CA, Feig M, Felli IC, Ferrari C, Forman-Kay JD, Gomes T, Gondelaud F, Gradinaru CC, Ha-Duong T, Head-Gordon T, Heidarsson PO, Janson G, Jeschke G, Leonardi E, Liu ZH, Longhi S, Lund XL, Macias MJ, Martin-Malpartida P, Mercadante D, Mouhand A, Nagy G, Nugnes MV, Perez-Canadillas JM, Pesce G, Pierattelli R, Piovesan D, Quaglia F, Ricard-Blum S, Robustelli P, Sagar A, Salladini E, Senicourt L, Sibille N, Teixeira JMC, Tsangaris TE, Varadi M, Nucleic Acids Res, 2023
3D chromatin interactions involving Drosophila insulators are infrequent but preferential and arise before TADs and transcription
Messina O, Raynal F, Gurgo J, Fiche JB, Pancaldi V, Nollmann M, Nat Commun, 2023
A cyclin-dependent kinase-mediated phosphorylation switch of disordered protein condensation
Valverde JM, Dubra G, Phillips M, Haider A, Elena-Real C, Fournet A, Alghoul E, Chahar D, Andres-Sanchez N, Paloni M, Bernado P, van Mierlo G, Vermeulen M, van den Toorn H, Heck AJR, Constantinou A, Barducci A, Ghosh K, Sibille N, Knipscheer P, Krasinska L, Fisher D, Altelaar M, Nat Commun, 2023
wTSA-CRAFT: an open-access web server for rapid analysis of thermal shift assay experiments
Reys V, Kowalewski J, Gelin M, Lionne C, Bioinform Adv, 2023
Development of LM-41 and AF-2112, two flufenamic acid-derived TEAD inhibitors obtained through the replacement of the trifluoromethyl group by aryl rings
Fnaiche A, Melin L, Suarez NG, Paquin A, Vu V, Li F, Allali-Hassani A, Bolotokova A, Allemand F, Gelin M, Cotelle P, Woo S, LaPlante SR, Barsyte-Lovejoy D, Santhakumar V, Vedadi M, Guichou JF, Annabi B, Gagnon A, Bioorg Med Chem Lett, 2023
Adaptive evolution in virulence effectors of the rice blast fungus Pyricularia oryzae
Le Naour-Vernet M, Charriat F, Gracy J, Cros-Arteil S, Ravel S, Veillet F, Meusnier I, Padilla A, Kroj T, Cesari S, Gladieux P, PLoS Pathog, 2023
Multi-scale dynamic imaging reveals that cooperative motility behaviors promote efficient predation in bacteria
Rombouts S, Mas A, Le Gall A, Fiche JB, Mignot T, Nollmann M, Nat Commun, 2023
Phosphorylation motif dictates GPCR C-terminal domain conformation and arrestin interaction
Guillien M, Mouhand A, Sagar A, Fournet A, Allemand F, Pereira GAN, Thureau A, Bernado P, Baneres JL, Sibille N, Structure, 2023
The novel cyclophilin inhibitor C105SR reduces hepatic ischaemia-reperfusion injury via mitoprotection
Kheyar A, Ahnou N, Ahmed-Belkacem A, Hulin A, Pressiat C, Ghaleh B, Guichou JF, Morin D, Pawlotsky JM, Teixeira-Clerc F, JHEP Rep, 2023
Does a Similar 3D Structure Mean a Similar Folding Pathway? The Presence of a C-Terminal alpha-Helical Extension in the 3D Structure of MAX60 Drastically Changes the Folding Pathway Described for Other MAX-Effectors from Magnaporthe oryzae
Lahfa M, Mouhand A, deGuillen K, Barthe P, Kroj T, Padilla A, Roumestand C, Molecules, 2023
Site-Specific Introduction of Alanines for the Nuclear Magnetic Resonance Investigation of Low-Complexity Regions and Large Biomolecular Assemblies
Elena-Real CA, Urbanek A, Imbert L, Morato A, Fournet A, Allemand F, Sibille N, Boisbouvier J, Bernado P, ACS Chem Biol, 2023
Isothermal self-assembly of multicomponent and evolutive DNA nanostructures
Rossi-Gendron C, El Fakih F, Bourdon L, Nakazawa K, Finkel J, Triomphe N, Chocron L, Endo M, Sugiyama H, Bellot G, Morel M, Rudiuk S, Baigl D, Nat Nanotechnol, 2023
Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMPDHs
Gedeon A, Ayoub N, Brule S, Raynal B, Karimova G, Gelin M, Mechaly A, Haouz A, Labesse G, Munier-Lehmann H, Protein Sci, 2023
Data-driven large-scale genomic analysis reveals an intricate phylogenetic and functional landscape in J-domain proteins
Malinverni D, Zamuner S, Rebeaud ME, Barducci A, Nillegoda NB, De Los Rios P, Proc Natl Acad Sci U S A, 2023
Structure, dynamics and transferability of the metal-dependent polyhistidine tetramerization motif TetrHis for single-chain Fv antibodies
Healey RD, Couillaud L, Hoh F, Mouhand A, Fouillen A, Couvineau P, Granier S, Leyrat C, Commun Chem, 2023
Linkers in fragment-based drug design: an overview of the literature
Grenier D, Audebert S, Preto J, Guichou JF, Krimm I, Expert Opin Drug Discov, 2023
Insights into the structure, functional perspective, and pathogenesis of ZIKV: an updated review
Bhat EA, Ali T, Sajjad N, Kumar R, Bron P, Biomed Pharmacother, 2023
1H, 13C and 15N backbone and side-chain resonance assignments of BmSA1, the surface antigen of Babesia microti
Mouhand A, Pissarra J, Delbecq S, Roumestand C, Barthe P, Biomol NMR Assign, 2023
SecretoMyc, a web-based database on mycobacteria secreted proteins and structure-based homology identification using bio-informatics tools
Gracy J, Vallejos-Sanchez K, Cohen-Gonsaud M, Tuberculosis (Edinb), 2023
Cyclophilin A Isomerisation of Septin 2 Mediates Abscission during Cytokinesis
Gorry RL, Brennan K, Lavin PTM, Mazurski T, Mary C, Matallanas D, Guichou JF, Mc Gee MM, Int J Mol Sci, 2023
Phase separation and molecular ordering of the prion-like domain of the Arabidopsis thermosensory protein EARLY FLOWERING 3
Hutin S, Kumita JR, Strotmann VI, Dolata A, Ling WL, Louafi N, Popov A, Milhiet PE, Blackledge M, Nanao MH, Wigge PA, Stahl Y, Costa L, Tully MD, Zubieta C, Proc Natl Acad Sci U S A, 2023
Development of new approach methods for the identification and characterization of endocrine metabolic disruptors-a PARC project
Braeuning A, Balaguer P, Bourguet W, Carreras-Puigvert J, Feiertag K, Kamstra JH, Knapen D, Lichtenstein D, Marx-Stoelting P, Rietdijk J, Schubert K, Spjuth O, Stinckens E, Thedieck K, van den Boom R, Vergauwen L, von Bergen M, Wewer N, Zalko D, Front Toxicol, 2023
Structural analysis of the Candida albicans mitochondrial DNA maintenance factor Gcf1p reveals a dynamic DNA-bridging mechanism
Tarres-Sole A, Battistini F, Gerhold JM, Pietrement O, Martinez-Garcia B, Ruiz-Lopez E, Lyonnais S, Bernado P, Roca J, Orozco M, Le Cam E, Sedman J, Sola M, Nucleic Acids Res, 2023
Concerted conformational changes control metabotropic glutamate receptor activity
Lecat-Guillet N, Quast RB, Liu H, Bourrier E, Moller TC, Rovira X, Soldevila S, Lamarque L, Trinquet E, Liu J, Pin JP, Rondard P, Margeat E, Sci Adv, 2023
Multi-site-specific isotopic labeling accelerates high-resolution structural investigations of pathogenic huntingtin exon-1
Elena-Real CA, Urbanek A, Lund XL, Morato A, Sagar A, Fournet A, Estana A, Bellande T, Allemand F, Cortes J, Sibille N, Melki R, Bernado P, Structure, 2023
Pharmacological activation of PIEZO1 in human red blood cells prevents Plasmodium falciparum invasion
Lohia R, Allegrini B, Berry L, Guizouarn H, Cerdan R, Abkarian M, Douguet D, Honore E, Wengelnik K, Cell Mol Life Sci, 2023
Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair
Alghoul E, Paloni M, Takedachi A, Urbach S, Barducci A, Gaillard PH, Basbous J, Constantinou A, Mol Cell, 2023

View all publications

CBS Teams

Structure, Dynamics and Function of biomolecules by NMR

Christian Roumestand and Nathalie Declerck
Structure and function of highly flexible proteins

Pau Bernadó and Nathalie Sibille
Multi-scale structural biology

Patrick Bron
ABCIS

Gilles Labesse
Nuclear Receptors as Integrators of Endogenous and Environmental Signals

William Bourguet and Albane Le Maire
Multiscale Biomolecular Modeling

Alessandro Barducci
Mechanisms of DNA Segregation and Remodelling

Marcelo Nollmann
Physics and mechanics of biological systems

Manouk Abkarian and Francesco Pedaci
Integrative Biophysics of Membranes

Pierre-Emmanuel Milhiet and Emmanuel Margeat
Synthetic Biology

Jérôme Bonnet and Martin Cohen-Gonsaud
Multiscale Biomolecular Modeling

Alessandro Barducci
Chromosome structure and homologous recombination in meiosis

Thomas Robert
Functional and synthetic genomics

Guillaume Cambray
Structure and function of the aryl hydrocarbon receptor

Jakub Gruszczyk

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