![Join the qbio Master's Program [Quantitative Biology: Molecular Mechanisms of Living Systems (parcours IDIL)] Q&A Session on Monday, February 10!](https://www.cbs.cnrs.fr/cache/mod_bt_contentslider/3e10f899c82679e1992f2a701c367d27-qbio_IDIL_quadri_16x10.png "Join the qbio Master's Program [Quantitative Biology: Molecular Mechanisms of Living Systems (parcours IDIL)] Q&A Session on Monday, February 10!")
Adapting the Charge Flipping algorithm to biological macromolecule diffraction data :
* ab initio determination of protein crystal structures at atomic resolution
* heavy atom or anomalous scatterers substructure determination
Dumas C. & van der Lee A. (2008) "Macromolecular structure solution by charge flipping", Acta Cryst D64, 864-873.
Palatinus L. & Chapuis G. (2007) "SUPERFLIP, a computer program for the solution of crystal structures by charge flipping in arbitrary dimensions", J. Appl. Cryst.40,786-790.
