Vanessa Delfosse
ABCIS: Atelier de Bio & Chimie Informatique Structurale
04 67 41 79 10
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Liste des publications
2025
2024
2021
Structure-Based and Knowledge-Informed Design of B-Raf Inhibitors Devoid of Deleterious PXR Binding
Schneider M, Delfosse V, Gelin M, Grimaldi M, Granell M, Heriaud L, Pons JL, Cohen Gonsaud M, Balaguer P, Bourguet W, Labesse G, J Med Chem, 2021
Functional analyses of phosphatidylserine/PI(4)P exchangers with diverse lipid species and membrane contexts reveal unanticipated rules on lipid transfer
Ikhlef S, Lipp NF, Delfosse V, Fuggetta N, Bourguet W, Magdeleine M, Drin G, BMC Biol, 2021
Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures
Delfosse V, Huet T, Harrus D, Granell M, Bourguet M, Gardia-Parege C, Chiavarina B, Grimaldi M, Le Mevel S, Blanc P, Huang D, Gruszczyk J, Demeneix B, Cianferani S, Fini JB, Balaguer P, Bourguet W, Proc Natl Acad Sci U S A, 2021
2020
2019
Insights into the activation mechanism of human estrogen-related receptor gamma by environmental endocrine disruptors
Thouennon E, Delfosse V, Bailly R, Blanc P, Boulahtouf A, Grimaldi M, Barducci A, Bourguet W, Balaguer P, Cell Mol Life Sci, 2019
Mechanisms of endocrine disruption through nuclear receptors and related pathways
Balaguer P, Delfosse V, Bourguet W, Curr Opin Endocr Metab Res, 2019
2017
2016
2015
Synergistic activation of human pregnane X receptor by binary cocktails of pharmaceutical and environmental compounds
Delfosse V, Dendele B, Huet T, Grimaldi M, Boulahtouf A, Gerbal-Chaloin S, Beucher B, Roecklin D, Muller C, Rahmani R, Cavailles V, Daujat-Chavanieu M, Vivat V, Pascussi JM, Balaguer P, Bourguet W, Nat Commun, 2015
Combining `dry' co-crystallization and in situ diffraction to facilitate ligand screening by X-ray crystallography
Gelin M, Delfosse V, Allemand F, Hoh F, Sallaz-Damaz Y, Pirocchi M, Bourguet W, Ferrer JL, Labesse G, Guichou JF, Acta Crystallogr D Biol Crystallogr, 2015
Reporter cell lines to evaluate the selectivity of chemicals for human and zebrafish estrogen and peroxysome proliferator activated gamma receptors
Grimaldi M, Boulahtouf A, Delfosse V, Thouennon E, Bourguet W, Balaguer P, Front Neurosci, 2015
Reporter Cell Lines for the Characterization of the Interactions between Human Nuclear Receptors and Endocrine Disruptors
Grimaldi M, Boulahtouf A, Delfosse V, Thouennon E, Bourguet W, Balaguer P, Front Endocrinol (Lausanne), 2015
INTRACELLULAR TRANSPORT. Phosphatidylserine transport by ORP/Osh proteins is driven by phosphatidylinositol 4-phosphate
Moser von Filseck J, Copic A, Delfosse V, Vanni S, Jackson CL, Bourguet W, Drin G, Science, 2015
An Unexpected Mode Of Binding Defines BMS948 as A Full Retinoic Acid Receptor beta (RARbeta, NR1B2) Selective Agonist
Nadendla E, Teyssier C, Delfosse V, Vivat V, Krishnasamy G, Gronemeyer H, Bourguet W, Germain P, PLoS ONE, 2015
2014
Structural and Functional Profiling of Environmental Ligands for Estrogen Receptors
Delfosse V, Grimaldi M, Cavailles V, Balaguer P, Bourguet W, Environ Health Perspect, 2014
Nuclear receptor profiling of bisphenol-a and its halogenated analogues
Delfosse V, Grimaldi M, le Maire A, Bourguet W, Balaguer P, Vitam Horm, 2014
A structural perspective on nuclear receptors as targets of environmental compounds
Delfosse V, Maire AL, Balaguer P, Bourguet W, Acta Pharmacol Sin, 2014