Robert Quast
Structure et Dynamique d’Assemblages Membranaires
04 67 41 77 14
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Liste des publications
2023
Concerted conformational changes control metabotropic glutamate receptor activity
Lecat-Guillet N, Quast RB, Liu H, Bourrier E, Moller TC, Rovira X, Soldevila S, Lamarque L, Trinquet E, Liu J, Pin JP, Rondard P, Margeat E, Sci Adv, 2023
Reliability and accuracy of single-molecule FRET studies for characterization of structural dynamics and distances in proteins
Agam G, Gebhardt C, Popara M, Machtel R, Folz J, Ambrose B, Chamachi N, Chung SY, Craggs TD, de Boer M, Grohmann D, Ha T, Hartmann A, Hendrix J, Hirschfeld V, Hubner CG, Hugel T, Kammerer D, Kang HS, Kapanidis AN, Krainer G, Kramm K, Lemke EA, Lerner E, Margeat E, Martens K, Michaelis J, Mitra J, Moya Munoz GG, Quast RB, Robb NC, Sattler M, Schlierf M, Schneider J, Schroeder T, Sefer A, Tan PS, Thurn J, Tinnefeld P, van Noort J, Weiss S, Wendler N, Zijlstra N, Barth A, Seidel CAM, Lamb DC, Cordes T, Nat Methods, 2023
2022
A modular spring-loaded actuator for mechanical activation of membrane proteins
Mills A, Aissaoui N, Maurel D, Elezgaray J, Morvan F, Vasseur JJ, Margeat E, Quast RB, Lai-Kee-Him J, Saint N, Benistant C, Nord A, Pedaci F, Bellot G, Nat Commun, 2022
Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations
Nasrallah C, Cannone G, Briot J, Rottier K, Berizzi AE, Huang CY, Quast RB, Hoh F, Baneres JL, Malhaire F, Berto L, Dumazer A, Font-Ingles J, Gomez-Santacana X, Catena J, Kniazeff J, Goudet C, Llebaria A, Pin JP, Vinothkumar KR, Lebon G, Cell Rep, 2022
2021
Allosteric modulators enhance agonist efficacy by increasing the residence time of a GPCR in the active state
Cao AM, Quast RB, Fatemi F, Rondard P, Pin JP, Margeat E, Nat Commun, 2021
Single-molecule FRET on its way to structural biology in live cells
Quast RB, Margeat E, Nat Methods, 2021
2019
Studying GPCR conformational dynamics by single molecule fluorescence
Quast RB, Margeat E, Mol Cell Endocrinol, 2019
Accurate Determination of Human CPR Conformational Equilibrium by smFRET using Dual Orthogonal Non-Canonical Amino Acid Labeling
Quast RB, Fatemi F, Kranendonk M, Margeat E, Truan G, Chembiochem, 2019