Patrick Bron
Biologie Structurale Multi-échelles
04 67 41 77 29
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Liste des publications
2024
2023
The genome of a bunyavirus cannot be defined at the level of the viral particle but only at the scale of the viral population
Yvon M, German TL, Ullman DE, Dasgupta R, Parker MH, Ben-Mahmoud S, Verdin E, Gognalons P, Ancelin A, Lai Kee Him J, Girard J, Vernerey MS, Fernandez E, Filloux D, Roumagnac P, Bron P, Michalakis Y, Blanc S, Proc Natl Acad Sci U S A, 2023
Insights into the structure, functional perspective, and pathogenesis of ZIKV: an updated review
Bhat EA, Ali T, Sajjad N, Kumar R, Bron P, Biomed Pharmacother, 2023
Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization
Morichaud Z, Trapani S, Vishwakarma RK, Chaloin L, Lionne C, Lai-Kee-Him J, Bron P, Brodolin K, Nat Commun, 2023
Structures of the arginine-vasopressin and oxytocin receptor signaling complexes
Bous J, Fouillen A, Orcel H, Granier S, Bron P, Mouillac B, Vitam Horm, 2023
Structure-guided mutagenesis of the capsid protein indicates that a nanovirus requires assembled viral particles for systemic infection
Trapani S, Bhat EA, Yvon M, Lai-Kee-Him J, Hoh F, Vernerey MS, Pirolles E, Bonnamy M, Schoehn G, Zeddam JL, Blanc S, Bron P, PLoS Pathog, 2023
Disruption of influenza virus packaging signals results in various misassembled genome complexes
Girard J, Jakob C, Toews LK, Fuchs J, Pohlmann A, Franzke K, Kolesnikova L, Hess M, Jeney C, Beer M, Bron P, Schwemmle M, Bolte H, J. Virol, 2023
Fatty Acid Metabolism in Fungi
Bhat EA, Sajjad N, Bron P, Shah AM, Song Y, Fungal Lipid Biochemistry, 2023
2022
The Syp1/FCHo2 protein induces septin filament bundling through its intrinsically disordered domain
Ibanes S, El-Alaoui F, Lai-Kee-Him J, Cazevieille C, Hoh F, Lyonnais S, Bron P, Cipelletti L, Picas L, Piatti S, Cell Rep, 2022
Structure of the vasopressin hormone-V2 receptor-beta-arrestin1 ternary complex
Bous J, Fouillen A, Orcel H, Trapani S, Cong X, Fontanel S, Saint-Paul J, Lai-Kee-Him J, Urbach S, Sibille N, Sounier R, Granier S, Mouillac B, Bron P, Sci Adv, 2022
Thicker Ice Improves the Integrity and Angular Distribution of CDC48A Hexamers on Cryo-EM Grids
Huntington B, Zhao L, Bron P, Shahul Hameed UF, Arold ST, Qureshi BM, Front Mol Biosci, 2022
Structural basis for the allosteric inhibition of UMP kinase from Gram-positive bacteria, a promising antibacterial target
Walter P, Mechaly A, Bous J, Haouz A, England P, Lai-Kee-Him J, Ancelin A, Hoos S, Baron B, Trapani S, Bron P, Labesse G, Munier-Lehmann H, FEBS J, 2022
Cryo-EM structure of transcription termination factor Rho from Mycobacterium tuberculosis reveals bicyclomycin resistance mechanism
Saridakis E, Vishwakarma R, Lai-Kee-Him J, Martin K, Simon I, Cohen-Gonsaud M, Coste F, Bron P, Margeat E, Boudvillain M, Commun Biol, 2022
2021
Cryo-electron microscopy structure of the antidiuretic hormone arginine-vasopressin V2 receptor signaling complex
Bous J, Orcel H, Floquet N, Leyrat C, Lai-Kee-Him J, Gaibelet G, Ancelin A, Saint-Paul J, Trapani S, Louet M, Sounier R, Demene H, Granier S, Bron P, Mouillac B, Sci Adv, 2021
Modular Imaging Scaffold for Single-Particle Electron Microscopy
Aissaoui N, Lai-Kee-Him J, Mills A, Declerck N, Morichaud Z, Brodolin K, Baconnais S, Le Cam E, Charbonnier JB, Sounier R, Granier S, Ropars V, Bron P, Bellot G, ACS Nano, 2021
2020
Structural basis of nanobody recognition of grapevine fanleaf virus and of virus resistance loss
Orlov I, Hemmer C, Ackerer L, Lorber B, Ghannam A, Poignavent V, Hleibieh K, Sauter C, Schmitt-Keichinger C, Belval L, Hily JM, Marmonier A, Komar V, Gersch S, Schellenberger P, Bron P, Vigne E, Muyldermans S, Lemaire O, Demangeat G, Ritzenthaler C, Klaholz BP, Proc Natl Acad Sci USA, 2020
Post-production modifications of murine Mesenchymal Stem Cell (mMSC) derived Extracellular Vesicles (EVs) and impact on their cellular interaction
Le Saux S, Aarrass H, Lai-Kee-Him J, Bron P, Armengaud J, Miotello G, Bertrand-Michel J, Dubois E, Georges S, Faklaris O, Devoisselle JM, Legrand P, Chopineau J, Morille M, Biomaterials, 2020
2019
The cryo-electron microscopy structure of Broad Bean Stain Virus suggests a common capsid assembly mechanism among comoviruses
Lecorre F, Lai-Kee-Him J, Blanc S, Zeddam JL, Trapani S, Bron P, Virology, 2019
The HslV Protease from Leishmania major and Its Activation by C-terminal HslU Peptides
Kebe NM, Samanta K, Singh P, Lai-Kee-Him J, Apicella V, Payrot N, Lauraire N, Legrand B, Lisowski V, Mbang-Benet DE, Pages M, Bastien P, Kajava AV, Bron P, Hernandez JF, Coux O, Int J Mol Sci, 2019
Structural basis of nanobody-recognition of grapevine fanleaf virus and of virus resistance loss
Orlov I, Hemmer C, Ackerer L, Lorber B, Ghannam A, Poignavent V, Hleibieh K, Sauter C, Schmitt-Keichinger C, Belval L, Hily JM, Marmonier A, Komar V, Gersch S, Schellenberger P, Bron P, Vigne E, Muyldermans S, Lemaire O, Demangeat G, Ritzenthaler C, Klaholz B, BioRxiv 728907, 2019
2018
Cardanol-based polymer latex by radical aqueous miniemulsion polymerization
Li WSJ, Negrell C, Ladmiral V, Lai-Kee-Him J, Bron P, Lacroix-Desmazes P, Joly-Duhamela C, Caillol S, Polym. Chem, 2018
Nano-Porous Structures via Self-Assembly of Amphiphilic Triblock Copolymer: Influence of solvent and molecular weight
Nehache S, Semsarilar M, In M, Dieudonne-George P, Lai-Kee-Him J, Bron P, Quemener A D, Polym. Chem, 2018
2017
Programmable self-assembly of three-dimensional nanostructures from 10,000 unique components
Ong LL, Hanikel N, Yaghi OK, Grun C, Strauss MT, Bron P, Lai-Kee-Him J, Schueder F, Wang B, Wang P, Kishi JY, Myhrvold C, Zhu A, Jungmann R, Bellot G, Ke Y, Yin P, Nature, 2017
Angular reconstitution-based 3D reconstructions of nanomolecular structures from superresolution light-microscopy images
Salas D, Le Gall A, Fiche JB, Valeri A, Ke Y, Bron P, Bellot G, Nollmann M, Proc Natl Acad Sci USA, 2017
Biological Fate of Fe3O4 Core-Shell Mesoporous Silica Nanoparticles Depending on Particle Surface Chemistry
Rascol E, Daurat M, Da Silva A, Maynadier M, Dorandeu C, Charnay C, Garcia M, Lai-Kee-Him J, Bron P, Auffan M, Liu W, Angeletti B, Devoisselle JM, Guari Y, Gary-Bobo M, Chopineau J, Nanomaterials (Basel), 2017
Correction: Structural Insights into Viral Determinants of Nematode Mediated Grapevine fanleaf virus Transmission
Schellenberger P, Sauter C, Lorber B, Bron P, Trapani S, Bergdoll M, Marmonier A, Schmitt-Keichinger C, Lemaire O, Demangeat G, Ritzenthaler C, PLoS Pathog, 2017
Aromatic Biobased Polymer Latex from Cardanol
Ladmiral V, Jeannin R, Fernandes Lizarazu K, Lai-Kee-Him J, Bron P, Lacroix-Desmazes P, Caillol S, European Polymer Journal, 2017
In situ synthesis of Prussian blue nanoparticles within a biocompatible reverse micellar system for in vivo Cs+ uptake
Lavaud C, Kajdan M, Compte E, Maurel JC, Lai-Kee-Him J, Bron P, Oliviero E, Long J, Larionova J, Guari Y, New Journal of Chemistry, 2017
201Tl-labeled Prussian Blue and Au@Prussian Blue nanoprobes for SPEC-CT imaging: influence of the size, shape and coating on the biodistribution
Maurin-Pasturel G, Rascol E, Buisson M, Sevestre S, Lai-Kee-Him J, Bron P, Long J, Chopineau J, Guari Y, Larionova J, Inorg. Chem. Front, 2017
2016
2014
2013
Modeling and self-assembly behavior of PEG-PLA-PEG triblock copolymers in aqueous solution
Wu X, Li S, Coumes F, Darcos V, Lai Kee Him J, Bron P, Nanoscale, 2013
The backbone model of the Arabis mosaic virus reveals new insights into functional domains of Nepovirus capsid
Lai-Kee-Him J, Schellenberger P, Dumas C, Richard E, Trapani S, Komar V, Demangeat G, Ritzenthaler C, Bron P, J Struct Biol, 2013
Structure and DNA-binding properties of the Bacillus subtilis SpoIIIE DNA translocase revealed by single-molecule and electron microscopies
Cattoni DI, Thakur S, Godefroy C, Le Gall A, Lai-Kee-Him J, Milhiet PE, Bron P, Nollmann M, Nucleic Acids Res, 2013
MgATP regulates allostery and fiber formation in IMPDHs
Labesse G, Alexandre T, Vaupre L, Salard-Arnaud I, Him JL, Raynal B, Bron P, Munier-Lehmann H, Structure, 2013
2012
Distinct roles of metabotropic glutamate receptor dimerization in agonist activation and G-protein coupling.
El Moustaine D, Granier S, Doumazane E, Scholler P, Rahmeh R, Bron P, Mouillac B, Baneres JL, Rondard P, Pin JP, Proc. Natl. Acad. Sci. U.S.A., 2012
Structural insights into biased G protein-coupled receptor signaling revealed by fluorescence spectroscopy
Rahmeh R, Damian M, Cottet M, Orcel H, Mendre C, Durroux T, Sharma KS, Durand G, Pucci B, Trinquet E, Zwier JM, Deupi X, Bron P, Baneres JL, Mouillac B, Granier S, Proc Natl Acad Sci U S A, 2012
2011
The opening of the SPP1 bacteriophage tail, a prevalent mechanism in Gram-positive-infecting siphophages
Goulet A, Lai-Kee-Him J, Veesler D, Auzat I, Robin G, Shepherd DA, Ashcroft AE, Richard E, Lichiere J, Tavares P, Cambillau C, Bron P, J Biol Chem, 2011
Lactococcal phage p2 ORF35-Sak3 is an ATPase involved in DNA recombination and AbiK mechanism
Scaltriti E, Launay H, Genois MM, Bron P, Rivetti C, Grolli S, Ploquin M, Campanacci V, Tegoni M, Cambillau C, Moineau S, Masson JY, Mol Microbiol, 2011
Structural insights into viral determinants of nematode mediated Grapevine fanleaf virus transmission
Schellenberger P, Sauter C, Lorber B, Bron P, Trapani S, Bergdoll M, Marmonier A, Schmitt-Keichinger C, Lemaire O, Demangeat G, Ritzenthaler C, PLoS Pathog, 2011
2010
Structure and molecular assignment of Lactococcal phage TP901-1 baseplate
Bebeacua C, Bron P, Lai L, Skovgaard Vegge C, Brondsted L, Spinelli S, Campanacci V, Veesler D, van Heel M, Cambillau C, J Biol Chem, 2010
Solution and electron microscopy characterization of lactococcal phage baseplates expressed in Escherichia coli
Campanacci V, Veesler D, Lichiere J, Blangy S, Sciara G, Moineau S, van Sinderen D, Bron P, Cambillau C, J Struct Biol, 2010
Structural insights into the molecular mechanisms of cauliflower mosaic virus transmission by its insect vector
Hoh F, Uzest M, Drucker M, Plisson-Chastang C, Bron P, Blanc S, Dumas C, J Virol, 2010
Structure of lactococcal phage p2 baseplate and its mechanism of activation
Sciara G, Bebeacua C, Bron P, Tremblay D, Ortiz-Lombardia M, Lichiere J, van Heel M, Campanacci V, Moineau S, Cambillau C, Proc Natl Acad Sci U S A, 2010
Crystal structure of bacteriophage SPP1 distal tail protein (GP 19.1): a baseplate hub paradigm in gram+ infecting phages
Veesler D, Robin G, Lichiere J, Auzat I, Tavares P, Bron P, Campanacci V, Cambillau C, J Biol Chem, 2010
tmRNA-SmpB: a journey to the centre of the bacterial ribosome
Weis F, Bron P, Giudice E, Rolland JP, Thomas D, Felden B, Gillet R, EMBO J, 2010
Accommodation of tmRNA-SmpB into stalled ribosomes: a cryo-EM study
Weis F, Bron P, Rolland JP, Thomas D, Felden B, Gillet R, RNA, 2010
2008
Supramolecular organization of the yeast F1Fo-ATP synthase
Thomas D, Bron P, Weimann T, Dautant A, Giraud MF, Paumard P, Salin B, Cavalier A, Velours J, Brethes D, Biol Cell, 2008
Apo-Hsp90 coexists in two open conformational states in solution
Bron P, Giudice E, Rolland JP, Buey RM, Barbier P, Diaz JF, Peyrot V, Thomas D, Garnier C, Biol Cell, 2008
2D crystals. In Handbook of Cryopreparation
Bron P, Vonck J, Cryo-Preparation methods for electron microscopy. Cavalier A, Spehner, D., Humbel, B.M. CRC press, 2008
2005
Divalent ion-dependent swelling of tomato bushy stunt virus: a multi-approach study
Aramayo R, Merigoux C, Larquet E, Bron P, Perez J, Dumas C, Vachette P, Boisset N, Biochim Biophys Acta, 2005
Structure of the mature P3-virus particle complex of cauliflower mosaic virus revealed by cryo-electron microscopy
Plisson C, Uzest M, Drucker M, Froissart R, Dumas C, Conway J, Thomas D, Blanc S, Bron P, J Mol Biol, 2005
2003
2002
Molecular organization of Mason-Pfizer monkey virus capsids assembled from Gag polyprotein in Escherichia coli
Nermut MV, Bron P, Thomas D, Rumlova M, Ruml T, Hunter E, J Virol, 2002
Aquaglyceroporins, one channel for two molecules
Thomas D, Bron P, Ranchy G, Duchesne L, Cavalier A, Rolland JP, Raguenes-Nicol C, Hubert JF, Haase W, Delamarche C, Biochim Biophys Acta, 2002
2001
Structural aspects of retrovirus assembly
Nermut MV, Bron P, Thomas D, Zhang W, Jones IM, Rumlova M, Ruml T, Virus Research, 2001
Functional characterization of a microbial aquaglyceroporin
Froger A, Rolland JP, Bron P, Lagree V, Le Caherec F, Deschamps S, Hubert JF, Pellerin I, Thomas D, Delamarche C, Microbiology, 2001
Oligomerization of water and solute channels of the major intrinsic protein (MIP) family
Duchesne L, Deschamps S, Pellerin I, Lagree V, Froger A, Thomas D, Bron P, Delamarche C, Hubert JF, Kidney Int, 2001
1999
The 9 A projection structure of cytochrome b6f complex determined by electron crystallography
Bron P, Lacapere JJ, Breyton C, Mosser G, J Mol Biol, 1999
Oligomerization state of MIP proteins expressed in Xenopus oocytes as revealed by freeze-fracture electron-microscopy analysis
Bron P, Lagree V, Froger A, Rolland JP, Hubert JF, Delamarche C, Deschamps S, Pellerin I, Thomas D, Haase W, J Struct Biol, 1999
1998
1997
The fourier transform used as a tool to evaluate systems for digitizing electron images
Bron P, Rolland J-P, Thomas D, Micro. Microanal. Microstruc., 1997
MACS : automatic counting of objects based on shape recognition
Rolland JP, Bron P, Thomas D, Comput. Applic. Biosci., 1997