Nathalie Declerck
Structure, dynamique et fonction des biomolécules par RMN
04 67 41 79 11
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Liste des publications
2022
2021
Resolving the activation mechanism of the D99N antiterminator LicT protein
Yang Y, Gracy J, Declerck N, Demene H, J Struct Biol, 2021
Modular Imaging Scaffold for Single-Particle Electron Microscopy
Aissaoui N, Lai-Kee-Him J, Mills A, Declerck N, Morichaud Z, Brodolin K, Baconnais S, Le Cam E, Charbonnier JB, Sounier R, Granier S, Ropars V, Bron P, Bellot G, ACS Nano, 2021
2020
An oligomeric switch controls the Mrr-induced SOS response in E. coli
Bourges AC, Torres Montaguth OE, Tadesse W, Labesse G, Aertsen A, Royer CA, Declerck N, DNA Repair (Amst), 2020
Quantitative High-Resolution Imaging of Live Microbial Cells at High Hydrostatic Pressure
Bourges AC, Lazarev A, Declerck N, Rogers KL, Royer CA, Biophys J, 2020
NMR chemical shift assignment of a constitutively active fragment of the antitermination protein LicT
Yang Y, Declerck N, Demene H, Biomol NMR Assign, 2020
Structural Insights into of the Allosteric Activation of the LicT Antiterminator by PTS-Mediated Phosphorylation
Yang Y, Padilla A, deGuillen K, Mammri L, Gracy J, Declerck N, Demene H, Structure, 2020
2019
2017
High pressure activation of the Mrr restriction endonuclease in Escherichia coli involves tetramer dissociation
Bourges AC, Torres Montaguth OE, Ghosh A, Tadesse WM, Declerck N, Aertsen A, Royer CA, Nucleic Acids Res, 2017
Competitive folding of RNA structures at a termination / antitermination site
Ait-Bara S, Clerte C, Declerck N, Margeat E, RNA, 2017
2016
2013
Competitive folding of anti-terminator/terminator hairpins monitored by single molecule FRET
Clerte C, Declerck N, Margeat E, Nucleic Acids Res, 2013
Interactions in gene expression networks studied by two-photon fluorescence fluctuation spectroscopy
Declerck N, Royer CA, Meth Enzymol, 2013
The RYMV-encoded viral suppressor of RNA silencing P1 is a zinc-binding protein with redox-dependent flexibility
Gillet FX, Cattoni DI, Petiot-Becard S, Delalande F, Poignavent V, Brizard JP, Bessin Y, Dorsselaer AV, Declerck N, Sanglier-Cianferani S, Brugidou C, Vignols F, J Mol Biol, 2013
2012
Absolute quantification of gene expression in individual bacterial cells using two-photon fluctuation microscopy
Ferguson ML, Le Coq D, Jules M, Aymerich S, Declerck N, Royer CA, Anal Biochem, 2012
Reconciling molecular regulatory mechanisms with noise patterns of bacterial metabolic promoters in induced and repressed states
Ferguson ML, Le Coq D, Jules M, Aymerich S, Radulescu O, Declerck N, Royer CA, Proc Natl Acad Sci U S A, 2012
2011
2010
Combination of noncovalent mass spectrometry and traveling wave ion mobility spectrometry reveals sugar-induced conformational changes of central glycolytic genes repressor/DNA complex
Atmanene C, Chaix D, Bessin Y, Declerck N, Van Dorsselaer A, Sanglier-Cianferani S, Anal Chem, 2010
Physical basis of the inducer-dependent cooperativity of the Central glycolytic genes Repressor/DNA complex
Chaix D, Ferguson ML, Atmanene C, Van Dorsselaer A, Sanglier-Cianferani S, Royer CA, Declerck N, Nucleic Acids Res, 2010
2009
2008
Molecular basis for group-specific activation of the virulence regulator PlcR by PapR heptapeptides
Bouillaut L, Perchat S, Arold ST, Zorrilla S, Slamti L, Henry C, Gohar M, Declerck N, Lereclus D, Nucleic Acids Res, 2008
Structural mechanism of signal transduction between the RNA-binding domain and the phosphotransferase system regulation domain of the LicT antiterminator
Demene H, Ducat T, DeGuillen K, Birck C, Aymerich S, Kochoyan M, Declerck N, J Biol Chem, 2008
A phospho-sugar binding domain homologous to NagB enzymes regulates the activity of the central glycolytic genes repressor
Doan T, Martin L, Zorrilla S, Chaix D, Aymerich S, Labesse G, Declerck N, Proteins, 2008
Investigating transcriptional regulation by fluorescence spectroscopy, from traditional methods to state-of-the-art single-molecule approaches
Zorrilla S, Lillo MP, Chaix D, Margeat E, Royer CA, Declerck N, Ann N Y Acad Sci, 2008
Characterization of the control catabolite protein of gluconeogenic genes repressor by fluorescence cross-correlation spectroscopy and other biophysical approaches
Zorrilla S, Ortega A, Chaix D, Alfonso C, Rivas G, Aymerich S, Lillo MP, Declerck N, Royer CA, Biophys J, 2008
2007
Inducer-modulated cooperative binding of the tetrameric CggR repressor to operator DNA
Zorrilla S, Doan T, Alfonso C, Margeat E, Ortega A, Rivas G, Aymerich S, Royer CA, Declerck N, Biophys J, 2007
Structure of PlcR: Insights into virulence regulation and evolution of quorum sensing in Gram-positive bacteria
Declerck N, Bouillaut L, Chaix D, Rugani N, Slamti L, Hoh F, Lereclus D, Arold ST, Proc Natl Acad Sci U S A, 2007
Fructose-1,6-bisphosphate acts both as an inducer and as a structural cofactor of the central glycolytic genes repressor (CggR)
Zorrilla S, Chaix D, Ortega A, Alfonso C, Doan T, Margeat E, Rivas G, Aymerich S, Declerck N, Royer CA, Biochemistry, 2007
2006
2005
Activation of the LicT transcriptional antiterminator involves a domain swing/lock mechanism provoking massive structural changes
Graille M, Zhou CZ, Receveur-Brechot V, Collinet B, Declerck N, van Tilbeurgh H, J Biol Chem, 2005
A natural variant of Bacillus licheniformis alpha-amylase isolated from flour mill wastewaters sheds light on the origin of high thermostability
Shahhoseini M, Ziaee AA, Pourbabai AA, Ghaemi N, Declerck N, J Appl Microbiol, 2005
2003
Hyperthermostabilization of Bacillus licheniformis alpha-amylase and modulation of its stability over a 50 degrees C temperature range
Declerck N, Machius M, Joyet P, Wiegand G, Huber R, Gaillardin C, Protein Eng, 2003
Kinetic stabilization of Bacillus licheniformis alpha-amylase through introduction of hydrophobic residues at the surface
Machius M, Declerck N, Huber R, Wiegand G, J Biol Chem, 2003
2002
Engineering the thermostability of Bacillus licheniformis a-amylase
Declerck N, Machius M, Joyet P, Wiegand G, Huber R, Gaillardin C, Biologia, Bratislava, 2002
RNA recognition by transcriptional antiterminators of the BglG/SacY family: mapping of SacY RNA binding site
Declerck N, Minh NL, Yang Y, Bloch V, Kochoyan M, Aymerich S, J Mol Biol, 2002
1H, 15N and 13C backbone resonance assignments of the 40 kDa LicT-CAT-PRD1 protein
Ducat T, Declerck N, Kochoyan M, Demene H, J Biomol NMR, 2002
Solution structure of the LicT-RNA antitermination complex: CAT clamping RAT
Yang Y, Declerck N, Manival X, Aymerich S, Kochoyan M, Embo J, 2002
2001
Crystal structure of an activated form of the PTS regulation domain from the LicT transcriptional antiterminator
van Tilbeurgh H, Le Coq D, Declerck N, Embo J, 2001
Structural insights into the regulation of bacterial signalling proteins containing PRDs
van Tilbeurgh H, Declerck N, Curr Opin Struct Biol, 2001
Sites of positive and negative regulation in the Bacillus subtilis antiterminators LicT and SacY
Tortosa P, Declerck N, Dutartre H, Lindner C, Deutscher J, Le Coq D, Mol Microbiol, 2001
Dimer stabilization upon activation of the transcriptional antiterminator LicT
Declerck N, Dutartre H, Receveur V, Dubois V, Royer C, Aymerich S, van Tilbeurgh H, J Mol Biol, 2001
2000
1999
Refined solution structure and backbone dynamics of 15N-labeled C12A-p8MTCP1 studied by NMR relaxation
Barthe P, Chiche L, Declerck N, Delsuc MA, Lefevre JF, Malliavin T, Mispelter J, Stern MH, Lhoste JM, Roumestand C, J. Biomol. NMR., 1999
Backbone dynamics study of C12A-p8MTCP1 using the linear correlation approach at two magnetic field strengths. Effect of protein aggregation.
Barthe P, Declerck N, Delsuc MA, Lefevre JF, Roumestand C, J. Chim. Phys., 1999
Impact of the lysine-188 and aspartic acid-189 inversion on activity of trypsin
Briand L, Chobert JM, Gantier R, Declerck N, Tran V, Leonil J, Molle D, Haertle T, FEBS Lett, 1999
RNA recognition by transcriptional antiterminators of the BglG/SacY family: functional and structural comparison of the CAT domain from SacY and LicT
Declerck N, Vincent F, Hoh F, Aymerich S, van Tilbeurgh H, J Mol Biol, 1999
1998
1997
Regulation of trypsin activity by Cu2+ chelation of the substrate binding site
Briand L, Chobert JM, Tauzin J, Declerck N, Leonil J, Molle D, Tran V, Haertle T, Protein Eng, 1997
Hyperthermostable mutants of Bacillus licheniformis alpha-amylase: thermodynamic studies and structural interpretation
Declerck N, Machius M, Chambert R, Wiegand G, Huber R, Gaillardin C, Protein Eng, 1997
1995
1994
1992
1990
Use of amber suppressors to investigate the thermostability of Bacillus licheniformis alpha-amylase. Amino acid replacements at 6 histidine residues reveal a critical position at His-133
Declerck N, Joyet P, Gaillardin C, Masson JM, J Biol Chem, 1990
Overlapping reading frames at the LYS5 locus in the yeast Yarrowia lipolytica
Xuan JW, Fournier P, Declerck N, Chasles M, Gaillardin C, Mol Cell Biol, 1990