Josephine Lai Kee Him
Biologie Structurale Multi-échelles
04 67 41 77 06
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Liste des publications
2024
In situfate of Chikungunya virus replication organelles
Girard J, Le Bihan O, Lai-Kee-Him J, Girleanu M, Bernard E, Castellarin C, Chee M, Neyret A, Spehner D, Holy X, Favier A-L, Briant L, Bron P, J Virol, 2024
Free-Standing DNA Origami Superlattice to Facilitate Cryo-EM Visualization of Membrane Vesicles
Aissaoui N, Mills A, Lai-Kee-Him J, Triomphe N, Cece Q, Doucet C, Bonhoure A, Vidal M, Ke Y, Bellot G, J Am Chem Soc, 2024
Phosphorylation of the F-BAR protein Hof1 drives septin ring splitting in budding yeast
Varela Salgado M, Adriaans IE, Touati SA, Ibanes S, Lai-Kee-Him J, Ancelin A, Cipelletti L, Picas L, Piatti S, Nat Commun, 2024
2023
Structural Insights into the Activation of Human Aryl Hydrocarbon Receptor by the Environmental Contaminant Benzo[a]pyrene and Structurally Related Compounds
Kwong HS, Paloni M, Grandvuillemin L, Sirounian S, Ancelin A, Lai-Kee-Him J, Grimaldi M, Carivenc C, Lancey C, Ragan TJ, Hesketh EL, Balaguer P, Barducci A, Gruszczyk J, Bourguet W, J Mol Biol, 2023
Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization
Morichaud Z, Trapani S, Vishwakarma RK, Chaloin L, Lionne C, Lai-Kee-Him J, Bron P, Brodolin K, Nat Commun, 2023
Structure-guided mutagenesis of the capsid protein indicates that a nanovirus requires assembled viral particles for systemic infection
Trapani S, Bhat EA, Yvon M, Lai-Kee-Him J, Hoh F, Vernerey MS, Pirolles E, Bonnamy M, Schoehn G, Zeddam JL, Blanc S, Bron P, PLoS Pathog, 2023
2022
The Syp1/FCHo2 protein induces septin filament bundling through its intrinsically disordered domain
Ibanes S, El-Alaoui F, Lai-Kee-Him J, Cazevieille C, Hoh F, Lyonnais S, Bron P, Cipelletti L, Picas L, Piatti S, Cell Rep, 2022
Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex
Gruszczyk J, Grandvuillemin L, Lai-Kee-Him J, Paloni M, Savva CG, Germain P, Grimaldi M, Boulahtouf A, Kwong HS, Bous J, Ancelin A, Bechara C, Barducci A, Balaguer P, Bourguet W, Nat Commun, 2022
Structure of the vasopressin hormone-V2 receptor-beta-arrestin1 ternary complex
Bous J, Fouillen A, Orcel H, Trapani S, Cong X, Fontanel S, Saint-Paul J, Lai-Kee-Him J, Urbach S, Sibille N, Sounier R, Granier S, Mouillac B, Bron P, Sci Adv, 2022
A modular spring-loaded actuator for mechanical activation of membrane proteins
Mills A, Aissaoui N, Maurel D, Elezgaray J, Morvan F, Vasseur JJ, Margeat E, Quast RB, Lai-Kee-Him J, Saint N, Benistant C, Nord A, Pedaci F, Bellot G, Nat Commun, 2022
Structural basis for the allosteric inhibition of UMP kinase from Gram-positive bacteria, a promising antibacterial target
Walter P, Mechaly A, Bous J, Haouz A, England P, Lai-Kee-Him J, Ancelin A, Hoos S, Baron B, Trapani S, Bron P, Labesse G, Munier-Lehmann H, FEBS J, 2022
Cryo-EM structure of transcription termination factor Rho from Mycobacterium tuberculosis reveals bicyclomycin resistance mechanism
Saridakis E, Vishwakarma R, Lai-Kee-Him J, Martin K, Simon I, Cohen-Gonsaud M, Coste F, Bron P, Margeat E, Boudvillain M, Commun Biol, 2022
2021
Cryo-electron microscopy structure of the antidiuretic hormone arginine-vasopressin V2 receptor signaling complex
Bous J, Orcel H, Floquet N, Leyrat C, Lai-Kee-Him J, Gaibelet G, Ancelin A, Saint-Paul J, Trapani S, Louet M, Sounier R, Demene H, Granier S, Bron P, Mouillac B, Sci Adv, 2021
Mesenchymal stromal cells-derived extracellular vesicles alleviate systemic sclerosis via miR-29a-3p
Rozier P, Maumus M, Maria ATJ, Toupet K, Lai-Kee-Him J, Jorgensen C, Guilpain P, Noel D, J Autoimmun, 2021
Modular Imaging Scaffold for Single-Particle Electron Microscopy
Aissaoui N, Lai-Kee-Him J, Mills A, Declerck N, Morichaud Z, Brodolin K, Baconnais S, Le Cam E, Charbonnier JB, Sounier R, Granier S, Ropars V, Bron P, Bellot G, ACS Nano, 2021
2020
2019
The cryo-electron microscopy structure of Broad Bean Stain Virus suggests a common capsid assembly mechanism among comoviruses
Lecorre F, Lai-Kee-Him J, Blanc S, Zeddam JL, Trapani S, Bron P, Virology, 2019
The HslV Protease from Leishmania major and Its Activation by C-terminal HslU Peptides
Kebe NM, Samanta K, Singh P, Lai-Kee-Him J, Apicella V, Payrot N, Lauraire N, Legrand B, Lisowski V, Mbang-Benet DE, Pages M, Bastien P, Kajava AV, Bron P, Hernandez JF, Coux O, Int J Mol Sci, 2019
2018
Cardanol-based polymer latex by radical aqueous miniemulsion polymerization
Li WSJ, Negrell C, Ladmiral V, Lai-Kee-Him J, Bron P, Lacroix-Desmazes P, Joly-Duhamela C, Caillol S, Polym. Chem, 2018
Nano-Porous Structures via Self-Assembly of Amphiphilic Triblock Copolymer: Influence of solvent and molecular weight
Nehache S, Semsarilar M, In M, Dieudonne-George P, Lai-Kee-Him J, Bron P, Quemener A D, Polym. Chem, 2018
2017
Programmable self-assembly of three-dimensional nanostructures from 10,000 unique components
Ong LL, Hanikel N, Yaghi OK, Grun C, Strauss MT, Bron P, Lai-Kee-Him J, Schueder F, Wang B, Wang P, Kishi JY, Myhrvold C, Zhu A, Jungmann R, Bellot G, Ke Y, Yin P, Nature, 2017
Biological Fate of Fe3O4 Core-Shell Mesoporous Silica Nanoparticles Depending on Particle Surface Chemistry
Rascol E, Daurat M, Da Silva A, Maynadier M, Dorandeu C, Charnay C, Garcia M, Lai-Kee-Him J, Bron P, Auffan M, Liu W, Angeletti B, Devoisselle JM, Guari Y, Gary-Bobo M, Chopineau J, Nanomaterials (Basel), 2017
Aromatic Biobased Polymer Latex from Cardanol
Ladmiral V, Jeannin R, Fernandes Lizarazu K, Lai-Kee-Him J, Bron P, Lacroix-Desmazes P, Caillol S, European Polymer Journal, 2017
In situ synthesis of Prussian blue nanoparticles within a biocompatible reverse micellar system for in vivo Cs+ uptake
Lavaud C, Kajdan M, Compte E, Maurel JC, Lai-Kee-Him J, Bron P, Oliviero E, Long J, Larionova J, Guari Y, New Journal of Chemistry, 2017
201Tl-labeled Prussian Blue and Au@Prussian Blue nanoprobes for SPEC-CT imaging: influence of the size, shape and coating on the biodistribution
Maurin-Pasturel G, Rascol E, Buisson M, Sevestre S, Lai-Kee-Him J, Bron P, Long J, Chopineau J, Guari Y, Larionova J, Inorg. Chem. Front, 2017
Self-assembly of PS-PNaSS-PS triblock copolymers from solution to solid state
Sabrina N, Mona S, Martin I, Philippe DG, Lai-Kee-Him Josephine , Patrick B, Denis B, Andre And Quemener D, Damien , Polymer Chemistry, 2017
2016
2013
Structure and DNA-binding properties of the Bacillus subtilis SpoIIIE DNA translocase revealed by single-molecule and electron microscopies
Cattoni DI, Thakur S, Godefroy C, Le Gall A, Lai-Kee-Him J, Milhiet PE, Bron P, Nollmann M, Nucleic Acids Res, 2013
The backbone model of the Arabis mosaic virus reveals new insights into functional domains of Nepovirus capsid
Lai-Kee-Him J, Schellenberger P, Dumas C, Richard E, Trapani S, Komar V, Demangeat G, Ritzenthaler C, Bron P, J Struct Biol, 2013