2022
Structure of the vasopressin hormone-V2 receptor-beta-arrestin1 ternary complex
Bous J, Fouillen A, Orcel H, Trapani S, Cong X, Fontanel S, Saint-Paul J, Lai-Kee-Him J, Urbach S, Sibille N, Sounier R, Granier S, Mouillac B, Bron P, Sci Adv, 2022
Structure-based design, synthesis and biological evaluation of a NAD+analogue targeting Pseudomonas aeruginosa NAD kinase
Rahimova R, Nogaret P, Huteau V, Gelin M, Clement DA, Labesse G, Pochet S, Blanc-Potard AB, Lionne C, FEBS J, 2022
Evaluating and mitigating clinical samples matrix effects on TX-TL cell-free performance
Voyvodic PL, Conejero I, Mesmoudi K, Renard E, Courtet P, Cattoni DI, Bonnet J, Sci Rep, 2022
Low Complexity Induces Structure in Protein Regions Predicted as Intrinsically Disordered
Goncalves-Kulik M, Mier P, Kastano K, Cortes J, Bernado P, Schmid F, Andrade-Navarro MA, Biomolecules, 2022
Conformational buffering underlies functional selection in intrinsically disordered protein regions
Gonzalez-Foutel NS, Glavina J, Borcherds WM, Safranchik M, Barrera-Vilarmau S, Sagar A, Estana A, Barozet A, Garrone NA, Fernandez-Ballester G, Blanes-Mira C, Sanchez IE, de Prat-Gay G, Cortes J, Bernado P, Pappu RV, Holehouse AS, Daughdrill GW, Chemes LB, Nat Struct Mol Biol, 2022
Cell-Free Protein Synthesis from Exonuclease-Deficient Cellular Extracts Utilizing Linear DNA Templates
Sabeti Azad M, Cardoso Batista A, Faulon JL, Beisel CL, Bonnet J, Kushwaha M, J Vis Exp, 2022
PYK2 senses calcium through a disordered dimerization and calmodulin-binding element
Momin AA, Mendes T, Barthe P, Faure C, Hong S, Yu P, Kadare G, Jaremko M, Girault JA, Jaremko , Arold ST, Commun Biol, 2022
Design and in vitro characterization of RXR variants as tools to investigate the biological role of endogenous rexinoids
le Maire A, Rey M, Vivat V, Guee L, Blanc P, Malosse C, Chamot-Rooke J, Germain P, Bourguet W, J Mol Endocrinol, 2022
PeroxiHUB: A Modular Cell-Free Biosensing Platform Using H2O2as Signal Integrator
Soudier P, Zuniga A, Duigou T, Voyvodic PL, Bazi-Kabbaj K, Kushwaha M, Vendrell JA, Solassol J, Bonnet J, Faulon JL, ACS Synth Biol, 2022
Unravelling the Adaptation Mechanisms to High Pressure in Proteins
Calio A, Dubois C, Fontanay S, Koza MM, Hoh F, Roumestand C, Oger P, Peters J, Int J Mol Sci, 2022
A modular spring-loaded actuator for mechanical activation of membrane proteins
Mills A, Aissaoui N, Maurel D, Elezgaray J, Morvan F, Vasseur JJ, Margeat E, Quast RB, Lai Kee-Him J, Saint N, Benistant C, Nord A, Pedaci F, Bellot G, Nat Commun, 2022
Crystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation
Mary C, Soflaee MH, Kesavan R, Gelin M, Brown H, Zacharias G, Mathews TP, Lemoff A, Lionne C, Labesse G, Hoxhaj G, Mol Cell, 2022
Mechanical signatures of human colon cancers
Lopez-Crapez E, Costa L, Tosato G, Ramos J, Mazard T, Guiramand J, Thierry A, Colinge J, Milhiet PE, Benistant C, Sci Rep, 2022
A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins
Lazar N, Mesarich CH, Petit-Houdenot Y, Talbi N, Li de la Sierra-Gallay I, Zelie E, Blondeau K, Gracy J, Ollivier B, Blaise F, Rouxel T, Balesdent MH, Idnurm A, van Tilbeurgh H, Fudal I, PLoS Pathog, 2022
A flexible and original architecture of two unrelated zinc fingers underlies the role of the multitask P1 in RYMV spread
Poignavent V, Hoh F, Terral G, Yang Y, Gillet FX, Kim JH, Allemand F, Lacombe E, Brugidou C, Cianferani S, Demene H, Vignols F, J Mol Biol, 2022
The activity of the RGA5 sensor NLR from rice requires binding of its integrated HMA domain to effectors but not HMA domain self-interaction
Xi Y, Chalvon V, Padilla A, Cesari S, Kroj T, Mol Plant Pathol, 2022
Thicker Ice Improves the Integrity and Angular Distribution of CDC48A Hexamers on Cryo-EM Grids
Huntington B, Zhao L, Bron P, Shahul Hameed UF, Arold ST, Qureshi BM, Front Mol Biosci, 2022
Tailoring the NIR-II Photoluminescence of Single Thiolated Au25Nanoclusters by Selective Binding to Proteins
Bertorelle F, Wegner KD, Peri Bakuli M, Fakhouri H, Comby-Zerbino C, Sagar A, Bernado P, Resch-Genger U, Bonaci-Kouteck V, Le Guevel X, Antoine R, Chemistry, 2022
1H, 13C, 15N backbone and side-chain NMR assignments for three MAX effectors from Magnaporthe oryzae
Lahfa M, Padilla A, deGuillen K, Pissarra J, Raji M, Cesari S, Kroj T, Gladieux P, Roumestand C, Barthe P, Biomol NMR Assign, 2022
SLiMAn: An Integrative Web Server for Exploring Short Linear Motif-Mediated Interactions in Interactomes
Reys V, Labesse G, J Proteome Res, 2022
Dynamic stiffening of the flagellar hook
Nord AL, Biquet-Bisquert A, Abkarian M, Pigaglio T, Seduk F, Magalon A, Pedaci F, Nat Commun, 2022
The Impact of Space and Time on the Functional Output of the Genome
Nollmann M, Bennabi I, Gotz M, Gregor T, Cold Spring Harb Perspect Biol, 2022
Combining High-Pressure NMR and Geometrical Sampling to Obtain a Full Topological Description of Protein Folding Landscapes: Application to the Folding of Two MAX Effectors from Magnaporthe oryzae
Dubois C, Lahfa M, Pissarra J, deGuillen K, Barthe P, Kroj T, Roumestand C, Padilla A, Int J Mol Sci, 2022
Structural Insights into the Intrinsically Disordered GPCR C-Terminal Region, Major Actor in Arrestin-GPCR Interaction
Guillien M, Mouhand A, Fournet A, Gontier A, Marti Navia A, Cordeiro TN, Allemand F, Thureau A, Baneres JL, Bernado P, Sibille N, Biomolecules, 2022
Functional control of a 0.5 MDa TET aminopeptidase by a flexible loop revealed by MAS NMR
Gauto DF, Macek P, Malinverni D, Fraga H, Paloni M, Sucec I, Hessel A, Bustamante JP, Barducci A, Schanda P, Nat Commun, 2022
Toward the Design of Ligands Selective for the C-Terminal Domain of TEADs
Liberelle M, Toulotte F, Renault N, Gelin M, Allemand F, Melnyk P, Guichou JF, Cotelle P, J Med Chem, 2022
Relaxation time asymmetry in stator dynamics of the bacterial flagellar motor
Perez-Carrasco R, Franco-Onate MJ, Walter JC, Dorignac J, Geniet F, Palmeri J, Parmeggiani A, Walliser NO, Nord AL, Sci Adv, 2022
Structural insights into recognition of chemokine receptors by Staphylococcus aureusleukotoxins
Lambey P, Otun O, Cong X, Hoh F, Brunel L, Verdie P, Grison CM, Peysson F, Jeannot S, Durroux T, Bechara C, Granier S, Leyrat C, Elife, 2022
New recognition specificity in a plant immune receptor by molecular engineering of its integrated domain
Cesari S, Xi Y, Declerck N, Chalvon V, Mammri L, Pugniere M, Henriquet C, deGuillen K, Chochois V, Padilla A, Kroj T, Nat Commun, 2022
A Histone Deacetylase (HDAC) Inhibitor with Pleiotropic In Vitro Anti-Toxoplasmaand Anti-PlasmodiumActivities Controls Acute and Chronic ToxoplasmaInfection in Mice
Jublot D, Cavailles P, Kamche S, Francisco D, Fontinha D, Prudencio M, Guichou JF, Labesse G, Sereno D, Loeuillet C, Int J Mol Sci, 2022
Structural basis for the allosteric inhibition of UMP kinase from Gram-positive bacteria, a promising antibacterial target
Walter P, Mechaly A, Bous J, Haouz A, England P, Lai-Kee-Him J, Ancelin A, Hoos S, Baron B, Trapani S, Bron P, Labesse G, Munier-Lehmann H, FEBS J, 2022
Molecular and cellular insight into Escherichia coli SslE and its role during biofilm maturation
Corsini PM, Wang S, Rehman S, Fenn K, Sagar A, Sirovica S, Cleaver L, Edwards-Gayle CJC, Mastroianni G, Dorgan B, Sewell LM, Lynham S, Iuga D, Franks WT, Jarvis J, Carpenter GH, Curtis MA, Bernado P, Darbari VC, Garnett JA, NPJ Biofilms Microbiomes, 2022
Structural evolution of the ancient enzyme, dissimilatory sulfite reductase
Colman DR, Labesse G, Swapna GVT, Stefanakis J, Montelione GT, Boyd ES, Royer CA, Proteins, 2022
Cryo-EM structure of transcription termination factor Rho from Mycobacterium tuberculosis reveals bicyclomycin resistance mechanism
Saridakis E, Vishwakarma R, Lai-Kee-Him J, Martin K, Simon I, Cohen-Gonsaud M, Coste F, Bron P, Margeat E, Boudvillain M, Commun Biol, 2022
A FRET-Based Biosensor for the Src N-Terminal Regulatory Element
Iruela G, Fernandez A, Sagar A, Carvajal FJ, Bernado P, Pons M, Biosensors (Basel), 2022
Editorial: Flagellar Motors and Force Sensing in Bacteria
Baker MAB, Kojima S, Nord AL, Partridge JD, Front Microbiol, 2022
Differentially Optimized Cell-Free Buffer Enables Robust Expression from Unprotected Linear DNA in Exonuclease-Deficient Extracts
Batista AC, Levrier A, Soudier P, Voyvodic PL, Achmedov T, Reif-Trauttmansdorff T, DeVisch A, Cohen-Gonsaud M, Faulon JL, Beisel CL, Bonnet J, Kushwaha M, ACS Synth Biol, 2022