2018
Chloride ions stabilize the glutamate-induced active state of the metabotropic glutamate receptor 3
Tora AS, Rovira X, Cao AM, Cabaye A, Olofsson L, Malhaire F, Scholler P, Baik H, Van Eeckhaut A, Smolders I, Rondard P, Margeat E, Acher F, Pin JP, Goudet C, Neuropharmacology, 2018
A new method for tumor imaging by targeting cancer associated fibroblasts
Loktev A, Lindner T, Mier W, Debus J, Altmann A, Jager D, Giesel F, Kratochwil C, Barthe P, Roumestand C, Haberkorn U, J Nucl Med, 2018
Hybrid parallelization of a multi-tree path search algorithm: Application to highly-flexible biomolecules
Estana A, Molloy K, Vaisset M, Sibille S, Simeon T, Bernado P, Cortes J, Parallel computing, 2018
Pulling lipid tubes from supported bilayers unveils the underlying substrate contribution to the membrane mechanics
Gumi-Audenis B, Costa L, Ferrer-Tasies L, Ratera I, Ventosa N, Sanz F, Giannotti MI, Nanoscale, 2018
Functional and Structural Study of the Amino Acid Substitution in a Novel Familial Androgen Receptor Mutation (W752G) Responsible for Complete Androgen Insensitivity Syndrome
Paris F, Boulahtouf A, Kalfa N, Guibal MP, Gaspari L, Servant N, Bourguet W, Sultan C, Balaguer P, Sex Dev, 2018
Emerging fields in chaperone proteins: a French workshop
Mileo E, Ilbert M, Barducci A, Bordes P, Castanie-Cornet MP, Garnier C, Genevaux P, Gillet R, Goloubinoff P, Ochsenbein F, Richarme G, Iobbi-Nivol C, Giudici-Orticoni MT, Gontero B, Genest O, Biochimie, 2018
Structural determinants of the catalytic mechanism of Plasmodium CCT, a key enzyme of malaria lipid biosynthesis
Guca E, Nagy GN, Hajdu F, Marton L, Izrael R, Hoh F, Yang Y, Vial H, Vertessy BG, Guichou JF, Cerdan R, Sci Rep, 2018
Monitoring Unfolding of Titin I27 Single and Bi Domain with High-Pressure NMR Spectroscopy
Herrada I, Barthe P, Vanheusden M, DeGuillen K, Mammri L, Delbecq S, Rico F, Roumestand C, Biophys J, 2018
Oligomerization of a G protein-coupled receptor in neurons controlled by its structural dynamics
Mller TC, Hottin J, Clerte C, Zwier JM, Durroux T, Rondard P, Prezeau L, Royer CA, Pin JP, Margeat E, Kniazeff J, Sci Rep, 2018
Lipid tempering simulation of model biological membranes on parallel platforms
Cardelli C, Barducci A, Procacci P, Biochim Biophys Acta, 2018
Characterization of the anti-hepatitis C virus activity of new non-peptidic small-molecule cyclophilin inhibitors with a potential for broad anti-
Nevers Q, Ruiz I, Ahnou N, Donati F, Brillet R, Softic L, Chazal M, Jouvenet N, Fourati S, Baudesson C, Bruscella P, Gelin M, Guichou JF, Pawlotsky JM, Ahmed-Belkacem A, Antimicrob Agents Chemother, 2018
An engineered device for indoleacetic acid production under quorum sensing signals enables Cupriavidus pinatubonensis JMP134 to stimulate plant growth
Zuniga A, De la Fuente F, Federici F, Lionne C, Bonnet J, de Lorenzo V, Gonzalez B, ACS Synth Biol, 2018
Establishment of Constraints on Amyloid Formation Imposed by Steric Exclusion of Globular Domains
Azizyan RA, Garro A, Radkova Z, Anikeenko A, Bakulina A, Dumas C, Kajava AV, J Mol Biol, 2018
Protein Flexibility and Synergy of HMG Domains Underlie U-Turn Bending of DNA by TFAM in Solution
Rubio-Cosials A, Battistini F, Gansen A, Cuppari A, Bernado P, Orozco M, Langowski J, Toth K, Sola M, Biophys J, 2018
An automated design framework for multicellular recombinase logic
Guiziou S, Ulliana F, Moreau V, Leclere M, Bonnet J, ACS Synth Biol, 2018
Toward the Discovery of a Novel Class of YAPaTEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAPaTEAD ProteinaProtein Interface
Gibault F, Coevoet M, Sturbaut M, Farce A, Renault N, Allemand F, Guichou JF, Drucbert AS, Foulon C, Magnez R, Thuru X, Corvaisier M, Huet G, Chavatte P, Melnyk P, Bailly F, Cotelle P, Cancers (Basel), 2018
Single-molecule analysis reveals the mechanism of transcription activation in
Vishwakarma RK, Cao AM, Morichaud Z, Perumal AS, Margeat E, Brodolin K, Sci Adv, 2018
Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation
Lecointre C, Simon V, Kerneur C, Allemand F, Fournet A, Montarras I, Pons JL, Gelin M, Brignatz C, Urbach S, Labesse G, Roche S, Structure, 2018
Chaperones convert the energy from ATP into the nonequilibrium stabilization of native proteins
Goloubinoff P, Sassi AS, Fauvet B, Barducci A, De Los Rios P, Nat Chem Biol, 2018
Synthesis of aminophenylhydroxamate and aminobenzylhydroxamate derivatives and in vitro screening for antiparasitic and histone deacetylase inhibitory activity
Loeuillet C, Touquet B, Oury B, Eddaikra N, Pons JL, Guichou JF, Labesse G, Sereno D, Int J Parasitol Drugs Drug Resist, 2018
Sequence-dependent catalytic regulation of the SpoIIIE motor activity ensures directionality of DNA translocation
Chara O, Borges A, Milhiet PE, Nollmann M, Cattoni DI, Sci Rep, 2018
A General Strategy to Access Structural Information at Atomic Resolution in Polyglutamine Homorepeats
Urbanek A, Morato A, Allemand F, Delaforge E, Fournet A, Popovic M, Delbecq S, Sibille N, Bernado P, Angew Chem Int Ed Engl, 2018
Sequential Membrane Rupture and Vesiculation during Plasmodium berghei Gametocyte Egress from the Red Blood Cell
Andreadaki M, Hanssen E, Deligianni E, Claudet C, Wengelnik K, Mollard V, McFadden GI, Abkarian M, Braun-Breton C, Siden-Kiamos I, Sci Rep, 2018
Solution scattering approaches to dynamical ordering in biomolecular systems
Bernado P, Shimizu N, Zaccai G, Kamikubo H, Sugiyama M, Biochim Biophys Acta, 2018
The ancestral retinoic acid receptor was a low-affinity sensor triggering neuronal differentiation
Handberg-Thorsager M, Gutierrez-Mazariegos J, Arold ST, Kumar Nadendla E, Bertucci PY, Germain P, Tomancak P, Pierzchalski K, Jones JW, Albalat R, Kane MA, Bourguet W, Laudet V, Arendt D, Schubert M, Sci Adv, 2018
TADs are 3D structural units of higher-order chromosome organization in
Szabo Q, Jost D, Chang JM, Cattoni DI, Papadopoulos GL, Bonev B, Sexton T, Gurgo J, Jacquier C, Nollmann M, Bantignies F, Cavalli G, Sci Adv, 2018
A General Strategy to Access Atomic Resolution Structural Information in Poly-Glutamine Homo-Repeats
Bernado P, Urbanek A, Morato A, Allemand F, Delaforge E, Fournet A, Popovic M, Delbecq S, Sibille N, Angew Chem Int Ed Engl, 2018
Culex pipiens crossing type diversity is governed by an amplified and polymorphic operon of Wolbachia
Bonneau M, Atyame C, Beji M, Justy F, Cohen-Gonsaud M, Sicard M, Weill M, Nat Commun, 2018
A modular receptor platform to expand the sensing repertoire of bacteria
Chang HJ, Mayonove P, Zavala A, De Visch A, Minard P, Cohen-Gonsaud M, Jerome B, ACS Synth Biol, 2018
KNOTTIN: the database of inhibitor cystine knot scaffold after 10 years, toward a systematic structure modeling
Postic G, Gracy J, Perin C, Chiche L, Gelly JC, Nucleic Acids Res, 2018
Identification of allosteric inhibitors of the ecto-5'-nucleotidase (CD73) targeting the dimer interface
Rahimova R, Fontanel S, Lionne C, Jordheim LP, Peyrottes S, Chaloin L, PLoS Comput Biol, 2018
DNA Organization and Superesolved Segregation
Cattoni DI, Fiche JB, Le Gall A, Nollmann M, Methods Mol Biol, 2018
Blood rheological abnormalities in sickle cell anemia
Connes P, Renoux C, Romana M, Abkarian M, Joly P, Martin C, Hardy-Dessources MD, Ballas SK, Clin Hemorheol Microcirc, 2018
Noninvasive Structural Analysis of Intermediate Species During Fibrillation: An Application of Small-Angle X-Ray Scattering
Langkilde AE, Herranz-Trillo F, Bernado P, Vestergaard B, Methods Mol Biol, 2018
Screening for PPAR Non-Agonist Ligands Followed by Characterization of a Hit, AM-879, with Additional No-Adipogenic and cdk5-Mediated Phosphorylation Inhibition Properties
Ribeiro Filho HV, Bernardi Videira N, Bridi AV, Tittanegro TH, Helena Batista FA, de Carvalho Pereira JG, de Oliveira PSL, Bajgelman MC, Le Maire A, Figueira ACM, Front Endocrinol (Lausanne), 2018
Structural and functional evidences for the interactions between nuclear hormone receptors and endocrine disruptors at low doses
Balaguer P, Delfosse V, Grimaldi M, Bourguet W, C R Biol, 2018