2019
Site-Specific Isotopic Labeling (SSIL) - Access to High-Resolution Structural and Dynamic Information in Low Complexity Proteins
Urbanek A, Elena-Real CA, Popovic M, Morato A, Fournet A, Allemand F, Delbecq S, Sibille N, Bernado P, Chembiochem, 2019
Regulation of RXR-RAR Heterodimers by RXR- and RAR-Specific Ligands and Their Combinations
le Maire A, Teyssier C, Balaguer P, Bourguet W, Germain P, Cells, 2019
In silico predictions of endocrine disruptors properties
Schneider M, Pons JL, Labesse G, Bourguet W, Endocrinology, 2019
Small-molecule inhibitors of cyclophilins block opening of the mitochondrial permeability transition pore and protect mice from hepatic ischemia-reperfusion injury
Panel M, Ruiz I, Brillet R, Lafdil F, Teixeira-Clerc F, Nguyen CT, Calderaro J, Gelin M, Allemand F, Guichou JF, Ghaleh B, Ahmed-Belkacem A, Morin D, Pawlotsky JM, Gastroenterology, 2019
Double Monoubiquitination Modifies the Molecular Recognition Properties of p15
Gonzalez-Magana A, de Opakua AI, Merino N, Monteiro H, Diercks T, Murciano-Calles J, Luque I, Bernado P, Cordeiro TN, Biasio A, Blanco FJ, ACS Chem Biol, 2019
NMR chemical shift assignment of a constitutively active fragment of the antitermination protein LicT
Yang Y, Declerck N, Demene H, Biomol NMR Assign, 2019
The Ellagitannin Metabolite Urolithin C is a Glucose-Dependent Regulator of Insulin Secretion through L-type Calcium Channel Activation
Bayle M, Neasta J, Dall'Asta M, Gautheron G, Virsolvy A, Quignard JF, Youl E, Magous R, Guichou JF, Crozier A, Del Rio D, Cros G, Oiry C, Br J Pharmacol, 2019
NMR chemical shift backbone assignment of the viral protein P1 encoded by the African Rice Yellow Mottle Virus
Yang Y, Poignavent V, Gillet FX, Vignols F, Demene H, Biomol NMR Assign, 2019
Protein kinase B controls Mycobacterium tuberculosis growth via phosphorylation of the transcriptional regulator Lsr2 at threonine 112
Alqaseer K, Turapov O, Barthe P, Jagatia H, De Visch A, Roumestand C, Wegrzyn M, Bartek IL, Voskuil MI, O'Hare HM, Ajuh P, Bottrill AR, Witney AA, Cohen-Gonsaud M, Waddell SJ, Mukamolova GV, Mol Microbiol, 2019
Metabolic perceptrons for neural computing in biological systems
Pandi A, Koch M, Voyvodic PL, Soudier P, Bonnet J, Kushwaha M, Faulon JL, Nat Commun, 2019
Insights into Substrate and Inhibitor Selectivity among Human GLUT Transporters through Comparative Modeling and Molecular Docking
Salgado Ferreira R, Pons JL, Labesse G, ACS Omega, 2019
In situ Structure of Rotavirus VP1 RNA-Dependent RNA Polymerase
Jenni S, Salgado EN, Herrmann T, Li Z, Grant T, Grigorieff N, Trapani S, Estrozi LF, Harrison SC, J Mol Biol, 2019
Novel and selective TLR7 antagonists among the imidazo[1,2-a]pyrazines, imidazo[1,5-a]quinoxalines and pyrazolo[1,5-a]quinoxalines series
Bou Karroum N, Moarbess G, Guichou JF, Bonnet PA, Patinote C, Bouharoun-Tayoun H, Chamat S, Cuq P, Diab-Assaf M, Kassab I, Masquefa C, J Med Chem, 2019
Interplay of Protein Disorder in Retinoic Acid Receptor Heterodimer and Its Corepressor Regulates Gene Expression
Cordeiro TN, Sibille N, Germain P, Barthe P, Boulahtouf A, Allemand F, Bailly R, Vivat V, Ebel C, Barducci A, Bourguet W, le Maire A, Bernado P, Structure, 2019
Studying GPCR conformational dynamics by single molecule fluorescence
Quast RB, Margeat E, Mol Cell Endocrinol, 2019
Nonclassical Ligand-Independent Regulation of Go Protein by an Orphan Class C G-Protein-Coupled Receptor
Hajj M, De Vita T, Vol C, Renassia C, Bologna JC, Brabet I, Cazade M, Pastore M, Blahos J, Labesse G, Pin JP, Prezeau L, Mol Pharmacol, 2019
Increase in muscle power is associated with myofibrillar ATPase adaptations during resistance training
Philippe AG, Lionne C, Sanchez AMJ, Pagano AF, Candau R, Exp Physiol, 2019
DNA-segment-capture model for loop extrusion by structural maintenance of chromosome (SMC) protein complexes
Marko JF, De Los Rios P, Barducci A, Gruber S, Nucleic Acids Res, 2019
Folding of the Ig-Like Domain of the Dengue Virus Envelope Protein Analyzed by High-Hydrostatic-Pressure NMR at a Residue-Level Resolution
Saotome T, Doret M, Kulkarni M, Yang YS, Barthe P, Kuroda Y, Roumestand C, Biomolecules, 2019
Towards accurate high-throughput ligand affinity prediction by exploiting structural ensembles, docking metrics and ligand similarity
Schneider M, Pons JL, Bourguet W, Labesse G, Bioinformatics, 2019
Aromatic Ring Dynamics, Thermal Activation, and Transient Conformations of a 468 kDa Enzyme by Specific
Gauto DF, Macek P, Barducci A, Fraga H, Hessel A, Terauchi T, Gajan D, Miyanoiri Y, Boisbouvier J, Lichtenecker R, Kainosho M, Schanda P, J Am Chem Soc, 2019
PEPOP 2.0: new approaches to mimic non-continuous epitopes
Demolombe V, de Brevern AG, Felicori L, NGuyen C, Machado de Avila RA, Valera L, Jardin-Watelet B, Lavigne G, Lebreton A, Molina F, Moreau V, BMC Bioinformatics, 2019
A Tiny Change Makes a Big Difference in the Anti-Parasitic Activities of an HDAC Inhibitor
Loeuillet C, Touquet B, Guichou JF, Labesse G, Sereno D, Int J Mol Sci, 2019
Microfluidic blood vasculature replicas using backside lithography
Fenech M, Girod V, Claveria V, Meance S, Abkarian M, Charlot B, Lab Chip, 2019
Insights into the activation mechanism of human estrogen-related receptor γ by environmental endocrine disruptors
Thouennon E, Delfosse V, Bailly R, Blanc P, Boulahtouf A, Grimaldi M, Barducci A, Bourguet W, Balaguer P, Cell Mol Life Sci, 2019
Oncogenic mutations at the EGFR ectodomain structurally converge to remove a steric hindrance on a kinase-coupled cryptic epitope
Orellana L, Thorne AH, Lema R, Gustavsson J, Parisian AD, Hospital A, Cordeiro TN, Bernado P, Scott AM, Brun-Heath I, Lindahl E, Cavenee WK, Furnari FB, Orozco M, Proc Natl Acad Sci USA, 2019
Characterization of XPR1/SLC53A1 variants located outside of the SPX domain in patients with primary familial brain calcification
Lopez-Sanchez U, Nicolas G, Richard AC, Maltete D, Charif M, Ayrignac X, Goizet C, Touhami J, Labesse G, Battini JL, Sitbon M, Sci Rep, 2019
Plug-and-play metabolic transducers expand the chemical detection space of cell-free biosensors
Voyvodic PL, Pandi A, Koch M, Conejero I, Valjent E, Courtet P, Renard E, Faulon JL, Bonnet J, Nat Commun, 2019
Developmental control of plant Rho GTPase nano-organization by the lipid phosphatidylserine
Platre MP, Bayle V, Armengot L, Bareille J, Marques-Bueno MDM, Creff A, Maneta-Peyret L, Fiche JB, Nollmann M, Miege C, Moreau P, Martiniere A, Jaillais Y, Science, 2019
Microscopy-Based Chromosome Conformation Capture Enables Simultaneous Visualization of Genome Organization and Transcription in Intact Organisms
Cardozo Gizzi AM, Cattoni DI, Fiche JB, Espinola SM, Gurgo J, Messina O, Houbron C, Ogiyama Y, Papadopoulos GL, Cavalli G, Lagha M, Nollmann M, Mol Cell, 2019
Molecular Dynamics Simulations of the Allosteric Modulation of the Adenosine A2A Receptor by a Mini-G Protein
Renault P, Louet M, Marie J, Labesse G, Floquet N, Sci Rep, 2019
First-in-class allosteric inhibitors of bacterial IMPDHs
Alexandre T, Lupan A, Helynck O, Vichier-Guerre S, Dugue L, Gelin M, Haouz A, Labesse G, Munier-Lehmann H, Eur J Med Chem, 2019
The cryo-electron microscopy structure of Broad Bean Stain Virus suggests a common capsid assembly mechanism among comoviruses
Lecorre F, Lai-Kee-Him J, Blanc S, Zeddam JL, Trapani S, Bron P, Virology, 2019
Osmotic stress activates two reactive oxygen species pathways with distinct effects on protein nanodomains and diffusion
Martiniere A, Fiche JB, Smokvarska M, Mari S, Alcon C, Dumont X, Hematy K, Jaillais Y, Nollmann M, Maurel C, Plant Physiol, 2019
Nanoscale organization of tetraspanins during HIV-1 budding by correlative dSTORM/AFM
Dahmane S, Doucet C, Le Gall A, Chamontin C, Dosset P, Murcy F, Fernandez L, Salas D, Rubinstein E, Mougel M, Nollmann M, Milhiet PE, Nanoscale, 2019
Investigating the Formation of Structural Elements in Proteins Using Local Sequence-Dependent Information and a Heuristic Search Algorithm
Estana A, Ghallab M, Bernado P, Cortes J, Molecules, 2019
Complex wireframe DNA nanostructures from simple building blocks
Wang W, Chen S, An B, Huang K, Bai T, Xu M, Bellot G, Ke Y, Xiang Y, Wei B, Nat Commun, 2019
Accurate Determination of Human CPR Conformational Equilibrium by smFRET using Dual Orthogonal Non-Canonical Amino Acid Labeling
Quast RB, Fatemi F, Kranendonk M, Margeat E, Truan G, Chembiochem, 2019
The HslV Protease from
Kebe NM, Samanta K, Singh P, Lai-Kee-Him J, Apicella V, Payrot N, Lauraire N, Legrand B, Lisowski V, Mbang-Benet DE, Pages M, Bastien P, Kajava AV, Bron P, Hernandez JF, Coux O, Int J Mol Sci, 2019
A fluorogenic assay to monitor Rho-dependent termination of transcription
Nadiras C, Delaleau M, Schwartz A, Margeat E, Boudvillain M, Biochemistry, 2019
Structural basis for chemically-induced homodimerization of a single domain antibody
Lesne J, Chang HJ, De Visch A, Paloni M, Barthe P, Guichou JF, Mayonove P, Barducci A, Labesse G, Bonnet J, Cohen-Gonsaud M, Sci Rep, 2019
Realistic Ensemble Models of Intrinsically Disordered Proteins Using a Structure-Encoding Coil Database
Estana A, Sibille N, Delaforge E, Vaisset M, Cortes J, Bernado P, Structure, 2019
A revisited version of the apo structure of the ligand-binding domain of the human nuclear receptor retinoic X receptor α
Eberhardt J, McEwen AG, Bourguet W, Moras D, Dejaegere A, Acta Crystallogr F Struct Biol Commun, 2019
Disentangling the complexity of low complexity proteins
Mier P, Paladin L, Tamana S, Petrosian S, Hajdu-Soltesz B, Urbanek A, Gruca A, Plewczynski D, Grynberg M, Bernado P, Gaspari Z, Ouzounis CA, Promponas VJ, Kajava AV, Hancock JM, Tosatto SCE, Dosztanyi Z, Andrade-Navarro MA, Brief Bioinformatics, 2019
Hierarchical composition of reliable recombinase logic devices
Guiziou S, Mayonove P, Bonnet J, Nat Commun, 2019
Function, evolution, and structure of J-domain proteins
Kampinga HH, Andreasson C, Barducci A, Cheetham ME, Cyr D, Emanuelsson C, Genevaux P, Gestwicki JE, Goloubinoff P, Huerta-Cepas J, Kirstein J, Liberek K, Mayer MP, Nagata K, Nillegoda NB, Pulido P, Ramos C, De Los Rios P, Rospert S, Rosenzweig R, Sahi C, , Cell Stress Chaperones, 2019
Comprehensive classification of the plant non-specific lipid transfer protein superfamily towards its sequence-structure-function analysis
Fleury C, Gracy J, Gautier MF, Pons JL, Dufayard JF, Labesse G, Ruiz M, de Lamotte F, PeerJ, 2019
Coevolutionary Analysis of Protein Sequences for Molecular Modeling
Malinverni D, Barducci A, Methods Mol Biol, 2019
Imaging Artificial Membranes Using High-Speed Atomic Force Microscopy
Nasrallah H, Vial A, Pocholle N, Soulier J, Costa L, Godefroy C, Bourillot E, Lesniewska E, Milhiet PE, Methods Mol Biol, 2019
Exploring Protein Conformational Landscapes Using High-Pressure NMR
Roche J, Royer CA, Roumestand C, Meth Enzymol, 2019
SHEDding light on the role of Pragmin pseudo-kinases in cancer
Roche S, Lecointre C, Simon V, Labesse G, Am J Cancer Res, 2019