2020
An oligomeric switch controls the Mrr-induced SOS response in E. coli
Bourges AC, Torres Montaguth OE, Tadesse W, Labesse G, Aertsen A, Royer CA, Declerck N, DNA Repair (Amst), 2020
LifeTime and improving European healthcare through cell-based interceptive medicine
Rajewsky N, Almouzni G, Gorski SA, Aerts S, Amit I, Bertero MG, Bock C, Bredenoord AL, Cavalli G, Chiocca S, Clevers H, De Strooper B, Eggert A, Ellenberg J, Fernandez XM, Figlerowicz M, Gasser SM, Hubner N, Kjems J, Knoblich JA, Krabbe G, Lichter P, Linn, Nature, 2020
Molecular dissection of amyloid disaggregation by human HSP70
Wentink AS, Nillegoda NB, Feufel J, Ubartaitė G, Schneider CP, De Los Rios P, Hennig J, Barducci A, Bukau B, Nature, 2020
Author Correction: STEEP mediates STING ER exit and activation of signaling
Zhang BC, Nandakumar R, Reinert LS, Huang J, Laustsen A, Gao ZL, Sun CL, Jensen SB, Troldborg A, Assil S, Berthelsen MF, Scavenius C, Zhang Y, Windross SJ, Olagnier D, Prabakaran T, Bodda C, Narita R, Cai Y, Zhang CG, Stenmark H, Doucet CM, Noda T, Guo Z,, Nat Immunol, 2020
Fragment Linking Strategies for Structure-Based Drug Design
Bancet A, Raingeval C, Lomberget T, Le Borgne M, Guichou JF, Krimm I, J Med Chem, 2020
New Chemical Probe Targeting Bacterial NAD Kinase
Clement DA, Leseigneur C, Gelin M, Coelho D, Huteau V, Lionne C, Labesse G, Dussurget O, Pochet S, Molecules, 2020
Author Correction: Synchronous, Crosstalk-free Correlative AFM and Confocal Microscopies/Spectroscopies
Fernandes TFD, Saavedra-Villanueva O, Margeat E, Milhiet PE, Costa L, Sci Rep, 2020
Robust Cell-Free Expression of Sub-Pathological and Pathological Huntingtin Exon-1 for NMR Studies. General Approaches for the Isotopic Labeling of Low-Complexity Proteins
Morato A, Elena-Real CA, Popovic M, Fournet A, Zhang K, Allemand F, Sibille N, Urbanek A, Bernado P, Biomolecules, 2020
Unraveling Molecular Interactions in Liquid-Liquid Phase Separation of Disordered Proteins by Atomistic Simulations
Paloni M, Bailly R, Ciandrini L, Barducci A, J Phys Chem B, 2020
Speech can produce jet-like transport relevant to asymptomatic spreading of virus
Abkarian M, Mendez S, Xue N, Yang F, Stone HA, Proc Natl Acad Sci USA, 2020
PRDM9 activity depends on HELLS and promotes local 5-hydroxymethylcytosine enrichment
Imai Y, Biot M, Clement J, Teragaki M, Urbach S, Robert T, Baudat F, Grey C, de Massy B, Elife, 2020
RNA imaging in bacteria
Rombouts S, Nollmann M, FEMS Microbiol Rev, 2020
Amyloidogenicity as a driving force for the formation of functional oligomers
Azizyan RA, Wang W, Anikeenko A, Radkova Z, Bakulina A, Garro A, Charlier L, Dumas C, Ventura S, Kajava AV, J Struct Biol, 2020
[In silico profiling of protein kinases inhibitors]
Reys V, Labesse G, Med Sci (Paris), 2020
A Plasma Membrane Nanodomain Ensures Signal Specificity during Osmotic Signaling in Plants
Smokvarska M, Francis C, Platre MP, Fiche JB, Alcon C, Dumont X, Nacry P, Bayle V, Nollmann M, Maurel C, Jaillais Y, Martiniere A, Curr Biol, 2020
Rational programming of history-dependent logic in cellular populations
Zuniga A, Guiziou S, Mayonove P, Meriem ZB, Camacho M, Moreau V, Ciandrini L, Hersen P, Bonnet J, Nat Commun, 2020
G1/S transcription factors assemble in increasing numbers of discrete clusters through G1 phase
Black L, Tollis S, Fu G, Fiche JB, Dorsey S, Cheng J, Ghazal G, Notley S, Crevier B, Bigness J, Nollmann M, Tyers M, Royer CA, J Cell Biol, 2020
Predicting Secondary Structure Propensities in IDPs Using Simple Statistics from Three-Residue Fragments
Estana A, Barozet A, Mouhand A, Vaisset M, Zanon C, Fauret P, Sibille N, Bernado P, Cortes J, J Mol Biol, 2020
Circulating tumor DNA genomics reveals potential mechanisms of resistance to BRAF-targeted therapies in BRAF-mutant metastatic non-small cell lung cancer patients
Ortiz-Cuaran S, Mezquita L, Swalduz A, Aldea M, Mazieres J, Leonce C, Jovelet C, Pradines A, Avrillon V, Chumbi Flores WR, Lacroix L, Loriot Y, Westeel V, Ngo-Camus M, Tissot C, Raynaud C, Gervais R, Brain E, Monnet I, Giroux Leprieur E, Caramella C, Mahi, Clin Cancer Res, 2020
Inferring efficiency of translation initiation and elongation from ribosome profiling
Szavits-Nossan J, Ciandrini L, Nucleic Acids Res, 2020
Human and Zebrafish Nuclear Progesterone Receptors Are Differently Activated by Manifold Progestins
Garoche C, Aut-Aussa S, Boulahtouf A, Creusot N, Hinfray N, Bourguet W, Balaguer P, Brion F, Environ Sci Technol, 2020
Two Novel Cases of Resistance to Thyroid Hormone Due to
le Maire A, Bouhours-Nouet N, Soamalala J, Mirebeau-Prunier D, Paloni M, Guee L, Heron D, Mignot C, Illouz F, Joubert F, Briet C, Rodien P, Bourguet W, Flamant F, Guyot R, Thyroid, 2020
STEEP mediates STING ER exit and activation of signaling
Zhang BC, Nandakumar R, Reinert LS, Huang J, Laustsen A, Gao ZL, Sun CL, Jensen SB, Troldborg A, Assil S, Berthelsen MF, Scavenius C, Zhang Y, Windross SJ, Olagnier D, Prabakaran T, Bodda C, Narita R, Cai Y, Zhang CG, Stenmark H, Doucet CM, Noda T, Guo Z,, Nat Immunol, 2020
ATP-Driven Separation of Liquid Phase Condensates in Bacteria
Guilhas B, Walter JC, Rech J, David G, Walliser NO, Palmeri J, Mathieu-Demaziere C, Parmeggiani A, Bouet JY, Le Gall A, Nollmann M, Mol Cell, 2020
Flanking Regions Determine the Structure of the Poly-Glutamine in Huntingtin through Mechanisms Common among Glutamine-Rich Human Proteins
Urbanek A, Popovic M, Morato A, Estana A, Elena-Real CA, Mier P, Fournet A, Allemand F, Delbecq S, Andrade-Navarro MA, Cortes J, Sibille N, Bernado P, Structure, 2020
Probing Protein Interaction Networks by Combining MS-Based Proteomics and Structural Data Integration
Postic G, Marcoux J, Reys V, Andreani J, Vandenbrouck Y, Bousquet MP, Mouton-Barbosa E, Cianferani S, Burlet-Schiltz O, Guerois R, Labesse G, Tuffery P, J Proteome Res, 2020
Peroxisome proliferator-activated receptor gamma-ligand-binding domain mutations associated with familial partial lipodystrophy type 3 disrupt human trophoblast fusion and fibroblast migration
Shoaito H, Chauveau S, Gosseaume C, Bourguet W, Vigouroux C, Vatier C, Pienkowski C, Fournier T, Degrelle SA, J Cell Mol Med, 2020
High Content Screening Using New U2OS Reporter Cell Models Identifies Harmol Hydrochloride as a Selective and Competitive Antagonist of the Androgen Receptor
Dellal H, Boulahtouf A, Alaterre E, Cuenant A, Grimaldi M, Bourguet W, Gongora C, Balaguer P, Pourquier P, Cells, 2020
High-Resolution Photonic Force Microscopy Based on Sharp Nanofabricated Tips
Desgarceaux R, Santybayeva Z, Battistella E, Nord AL, Braun-Breton C, Abkarian M, Marago OM, Charlot B, Pedaci F, Nano Lett, 2020
Quantitative High-Resolution Imaging of Live Microbial Cells at High Hydrostatic Pressure
Bourges AC, Lazarev A, Declerck N, Rogers KL, Royer CA, Biophys J, 2020
Compression, Rupture, and Puncture of Model Membranes at the Molecular Scale
Saavedra V O, Fernandes TFD, Milhiet PE, Costa L, Langmuir, 2020
Structural basis of nanobody recognition of grapevine fanleaf virus and of virus resistance loss
Orlov I, Hemmer C, Ackerer L, Lorber B, Ghannam A, Poignavent V, Hleibieh K, Sauter C, Schmitt-Keichinger C, Belval L, Hily JM, Marmonier A, Komar V, Gersch S, Schellenberger P, Bron P, Vigne E, Muyldermans S, Lemaire O, Demangeat G, Ritzenthaler C, Klaho, Proc Natl Acad Sci USA, 2020
The GOLIATH Project: Towards an Internationally Harmonised Approach for Testing Metabolism Disrupting Compounds
Legler J, Zalko D, Jourdan F, Jacobs M, Fromenty B, Balaguer P, Bourguet W, Munic Kos V, Nadal A, Beausoleil C, Cristobal S, Remy S, Ermler S, Margiotta-Casaluci L, Griffin JL, Blumberg B, Chesne C, Hoffmann S, Andersson PL, Kamstra JH, Int J Mol Sci, 2020
Evidence of the Reduced Abundance of Proline cis Conformation in Protein Poly Proline Tracts
Urbanek A, Popovic M, Elena-Real CA, Morato A, Estana A, Fournet A, Allemand F, Gil AM, Cativiela C, Cortes J, Jimenez AI, Sibille N, Bernado P, J Am Chem Soc, 2020
Synchronous, Crosstalk-free Correlative AFM and Confocal Microscopies/Spectroscopies
Fernandes TFD, Saavedra O, Margeat E, Milhiet PE, Costa L, Sci Rep, 2020
Integrative Biophysics: Protein Interaction and Disorder
Yang S, Bernado P, J Mol Biol, 2020
NMR chemical shift assignment of a constitutively active fragment of the antitermination protein LicT
Yang Y, Declerck N, Demene H, Biomol NMR Assign, 2020
Disentangling the complexity of low complexity proteins
Mier P, Paladin L, Tamana S, Petrosian S, Hajdu-Soltesz B, Urbanek A, Gruca A, Plewczynski D, Grynberg M, Bernado P, Gaspari Z, Ouzounis CA, Promponas VJ, Kajava AV, Hancock JM, Tosatto SCE, Dosztanyi Z, Andrade-Navarro MA, Brief Bioinformatics, 2020
Site-Specific Isotopic Labeling (SSIL) - Access to High-Resolution Structural and Dynamic Information in Low Complexity Proteins
Urbanek A, Elena-Real CA, Popovic M, Morato A, Fournet A, Allemand F, Delbecq S, Sibille N, Bernado P, Chembiochem, 2020
From substrate to fragments to inhibitor active in vivo against Staphylococcus aureus
Gelin M, Paoletti J, Nahori MA, Huteau V, Leseigneur C, Jouvion G, Dugue L, Clement D, Pons JL, Assairi L, Pochet S, Labesse G, Dussurget O, ACS Infect Dis, 2020
Direct and simultaneous observation of transcription and chromosome architecture in single cells with Hi-M
Cardozo Gizzi AM, Espinola SM, Gurgo J, Houbron C, Fiche JB, Cattoni DI, Nollmann M, Nat Protoc, 2020
Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3
de Las Rivas M, Paul Daniel EJ, Narimatsu Y, Companon I, Kato K, Hermosilla P, Thureau A, Ceballos-Laita L, Coelho H, Bernado P, Marcelo F, Hansen L, Maeda R, Lostao A, Corzana F, Clausen H, Gerken TA, Hurtado-Guerrero R, Nat Chem Biol, 2020
TADs or no TADS: lessons from single-cell imaging visualization of chromosome architecture
Cardozo Gizzi AM, Cattoni DI, Nollmann M, J Mol Biol, 2020
Perspectives on Chromosome Organization
Nollmann M, Koszul R, J Mol Biol, 2020
Structural Insights into of the Allosteric Activation of the LicT Antiterminator by PTS-Mediated Phosphorylation
Yang Y, Padilla A, deGuillen K, Mammri L, Gracy J, Declerck N, Demene H, Structure, 2020
Corrigendum to "Fourier-space TEM reconstructions with symmetry adapted functions for all rotational point groups" [J. Struct. Biol. 182 (2013) 87-92]
Trapani S, Navaza J, J Struct Biol, 2020
Post-production modifications of murine Mesenchymal Stem Cell (mMSC) derived Extracellular Vesicles (EVs) and impact on their cellular interaction
Le Saux S, Aarrass H, Lai-Kee-Him J, Bron P, Armengaud J, Miotello G, Bertrand-Michel J, Dubois E, Georges S, Faklaris O, Devoisselle JM, Legrand P, Chopineau J, Morille M, Biomaterials, 2020
Coevolutionary Analysis of Protein Subfamilies by Sequence Reweighting
Malinverni D, Barducci A, Entropy (Basel), 2020
Towards accurate high-throughput ligand affinity prediction by exploiting structural ensembles, docking metrics and ligand similarity
Schneider M, Pons JL, Bourguet W, Labesse G, Bioinformatics, 2020
Synthetic receptors to understand and control cellular functions
Chang HJ, Bonnet J, Meth Enzymol, 2020
Physical Views on ParABS-Mediated DNA Segregation
Guilhas B, Le Gall A, Nollmann M, Adv Exp Med Biol, 2020
IDPs and their complexes in GPCR and nuclear receptor signaling
Guillien M, le Maire A, Mouhand A, Bernado P, Bourguet W, Baneres JL, Sibille N, Prog Mol Biol Transl Sci, 2020
Structural Characterization of Protein-Protein Interactions with pyDockSAXS
Jimenez-Garcia B, Bernado P, Fernandez-Recio J, Methods Mol Biol, 2020
Protein-protein interactions in the regulation of RAR-RXR heterodimers transcriptional activity
le Maire A, Germain P, Bourguet W, Meth Enzymol, 2020
The importance of definitions in the study of polyQ regions: A tale of thresholds, impurities and sequence context
Mier P, Elena-Real C, Urbanek A, Bernado P, Andrade-Navarro MA, Comput Struct Biotechnol J, 2020
Structural Analyses of Intrinsically Disordered Proteins by Small-Angle X-Ray Scattering
Sagar A, Svergun D, Bernado P, Methods Mol Biol, 2020