PIBBS publications




 

Pôle RMN



Saotome T, Doret M, Kulkarni M, Yang YS, Barthe P, Kuroda Y, Roumestand C Folding of the Ig-Like Domain of the Dengue Virus Envelope Protein Analyzed by High-Hydrostatic-Pressure NMR at a Residue-Level Resolution Biomolecules, 2019,9:8 PubMed Id 31357538

Yang Y, Poignavent V, Gillet FX, Vignols F, Demene H NMR chemical shift backbone assignment of the viral protein P1 encoded by the African Rice Yellow Mottle Virus Biomol NMR Assign 2019, 13 (2):345-348 PubMed Id 31346897

Gaillard S, Das S, Djibo M, Raviglione D, Roumestand C, Legrand B, Inguimbert N Towards the total synthesis of trichormamide A, a cyclic undecapeptide Tetrahedron Letters 2018,59(41):3713-3718

Guo L, Cesari S, deGuillen K, Chalvon V, Mammri L, Ma M, Meusnier I, Bonnot F, Padilla A, Peng YL, Liu J, Kroj T Specific recognition of two MAX effectors by integrated HMA domains in plant immune receptors involves distinct binding surfaces Proc Natl Acad Sci USA 2018, 115(45): 11637-11642 PubMed Id 30355769

Loktev A, Lindner T, Mier W, Debus J, Altmann A, Jager D, Giesel F, Kratochwil C, Barthe P, Roumestand C, Haberkorn U A Tumor-Imaging Method Targeting Cancer-Associated Fibroblasts J Nucl Med 2018, 59(9): 1423-1429 PubMed Id 29626120

Aldrian G, Vaissiere A, Konate K, Seisel Q, Vives E, Fernandez F, Viguier V, Genevois C, Couillaud F, Demene H, Aggad D, Covinhes A, Barrere-Lemaire S, Deshayes S, Boisguerin P PEGylation rate influences peptide-based nanoparticles mediated siRNA delivery in vitro and in vivo J Control Release 2017,256: 79-91 PubMed Id 28411182

Ortiz D, deGuillen K, Cesari S, Chalvon V, Gracy J, Padilla A, Kroj T Recognition of the Magnaporthe oryzae effector AVR-Pia by the decoy domain of the rice NLR immune receptor RGA5, Plant Cell 2017, 29(1): 156-168 PubMed Id 28087830

Sagnol S, Marchal S, Yang Y, Allemand F, de Stanta Barba P Epithelial Splicing Regulatory Protein 1 (ESRP1) is a new regulator of stomach smooth muscle development and plasticity Dev Biol 2016, 414 (2):207-18 PubMed Id 27108394

Toleikis Z, Sirotkin VA, Skvarnavicius G, SmirnovienÄ— J, Roumestand C, Matulis D, Petrauskas V Volume of Hsp90 Protein-Ligand Binding Determined by Fluorescent Pressure Shift Assay, Densitometry, and NMR J Phys Chem B 2016, 120(37):9903-12 PubMed Id 27571383

deGuillen K, Ortiz-Vallejo D, Gracy J, Fournier E, Kroj T, Padilla A Structure Analysis Uncovers a Highly Diverse but Structurally Conserved Effector Family in Phytopathogenic Fungi PLoS Pathog 2015, 11(10): e1005228 PubMed Id 26506000

Sounier R, Mas C, Steyaert J, Laeremans T, Manglik A, Huang W, Kobilka BK, Demene H, Granier S Propagation of conformational changes during μ-opioid receptor activation Nature 2015, 524 (7565): 375-8 PubMed Id 26245377

Turapov O, Loraine J, Jenkins CH, Barthe P, McFeely D, Forti F, Ghisotti D, Hesek D, Lee M, Bottrill AR, Vollmer W, Mobashery S, Cohen-Gonsaud M, Mukamolova GV The external PASTA domain of the essential serine/threonine protein kinase PknB regulates mycobacterial growth Open Biol 2015, 5:7 PubMed Id 26136255

De Biasio A, Ibanez de Opakua A, Cordeiro TN, Villate M, Merino N, Sibille N, Lelli M, Diercks T, Bernado P, Blanco FJ p15(PAF) Is an Intrinsically Disordered Protein with Nonrandom Structural Preferences at Sites of Interaction with Other Proteins Biophys J 2014, 106 ( 4): 865-74 PubMed Id 24559989

Yang Y, Allemand F, Guca E, Vallone B, Delbecq S, Roumestand C (1)H, (15)N and (13)C Backbone resonance assignments of murine met-neuroglobin, free and in complex with cyanide Biomol NMR Assign 2014, PubMed Id 24830543

Yang YS, Fernandez B, Lagorce A, Aloin V, deGuillen KM, Boyer JB, Dedieu A, Confalonieri F, Armengaud J, Roumestand CPrioritizing targets for structural biology through the lens of proteomics: The archaeal protein TGAM_1934 from Thermococcus gammatolerans Proteomics 2014, 9(1):153-6 PubMed Id 25359407






 

Pôle Microscopie électronique



Jenni S, Salgado EN, Herrmann T, Li Z, Grant T, Grigorieff N, Trapani S, Estrozi LF, Harrison SC In situ Structure of Rotavirus VP1 RNA-Dependent RNA Polymerase J Mol Biol 2019, 431, (17): 3124-3138 PubMed Id 31233764

Kebe NM, Samanta K, Singh P, Lai-Kee-Him J, Apicella V, Payrot N, Lauraire N, Legrand B, Lisowski V, Mbang-Benet DE, Pages M, Bastien P, Kajava AV, Bron P, Hernandez JF, Coux O The HslV Protease from Leishmania major and Its Activation by C-terminal HslU Peptides. , Int J Mol Sci 2019 20: 5 PubMed Id 30813632

Rascol E, Daurat M, Da Silva A, Maynadier M, Dorandeu C, Charnay C, Garcia M, Lai-Kee-Him J, Bron P, Auffan M, Liu W, Angeletti B, Devoisselle JM, Guari Y, Gary-Bobo M, Chopineau J Biological Fate of Fea‚ƒOa‚„ Core-Shell Mesoporous Silica Nanoparticles Depending on Particle Surface Chemistry, Nanomaterials (Basel), 2017, 7:7, PubMed Id 28665317

Dairi S, Madani K, Aoun M, Him JL, Bron P, Lauret C, Cristol JP, Carbonneau MA Antioxidative Properties and Ability of Phenolic Compounds of Myrtus communis Leaves to Counteract In Vitro LDL and Phospholipid Aqueous Dispersion Oxidation J Food Sci 2014, 79(7): C1260-70 PubMed Id 24962212




 

Pôle Cristallo/conception de drogues



Bayle M, Neasta J, Dall'Asta M, Gautheron G, Virsolvy A, Quignard JF, Youl E, Magous R, Guichou JF, Crozier A, Del Rio D, Cros G, Oiry C The Ellagitannin Metabolite Urolithin C is a Glucose-Dependent Regulator of Insulin Secretion through L-type Calcium Channel Activation Br J Pharmacol, 2019 in press

Alexandre T, Lupan A, Helynck O, Vichier-Guerre S, Dugue L, Gelin M, Haouz A, Labesse G, Munier-Lehmann H First-in-class allosteric inhibitors of bacterial IMPDHs Eur J Med Chem 2019, 167: 124-132 PubMed Id 30769241

Bou Karroum N, Moarbess G, Guichou JF, Bonnet PA, Patinote C, Bouharoun-Tayoun H, Chamat S, Cuq P, Diab-Assaf M, Kassab I, Masquefa C Novel and selective TLR7 antagonists among the imidazo[1,2-a]pyrazines, imidazo[1,5-a]quinoxalines and pyrazolo[1,5-a]quinoxalines series J Med Chem 2019, 62 (15) 7015-7031 PubMed Id 31283223

Guca E, Nagy GN, Hajdu F, Marton L, Izrael R, Hoh F, Yang Y, Vial H, Vertessy BG, Guichou JF, Cerdan R Structural determinants of the catalytic mechanism of Plasmodium CCT, a key enzyme of malaria lipid biosynthesis Sci Rep 2018, 8:1 PubMed Id 30046154

Gibault F, Coevoet M, Sturbaut M, Farce A, Renault N, Allemand F, Guichou JF, Drucbert AS, Foulon C, Magnez R, Thuru X, Corvaisier M, Huet G, Chavatte P, Melnyk P, Bailly F, Cotelle P Toward the Discovery of a Novel Class of YAPa-TEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAPaTEAD Proteina-Protein Interface Cancers (Basel) 2018,10:5 PubMed Id 29738494

Lecointre C, Simon V, Kerneur C, Allemand F, Fournet A, Montarras I, Pons JL, Gelin M, Brignatz C, Urbach S, Labesse G, Roche S Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation, Structure 2018, 26 (4): 545-554, PubMed Id 29503074

Loeuillet C, Touquet B, Oury B, Eddaikra N, Pons JL, Guichou JF, Labesse G, Sereno D Synthesis of aminophenylhydroxamate and aminobenzylhydroxamate derivatives and in vitro screening for antiparasitic and histone deacetylase inhibitory activity Int J Parasitol Drugs Drug Resist 2018, 8 (1): 59-66 PubMed Id 29414107

Vasiliauskaite-Brooks I, Healey RD, Rochaix P, Saint-Paul J, Sounier R, Grison C, Waltrich-Augusto T, Fortier M, Hoh F, Saied EM, Arenz C, Basu S, Leyrat C, Granier S Structure of a human intramembrane ceramidase explains enzymatic dysfunction found in leukodystrophy, Nat Commun 2018,9 (1): 5437 PubMed Id 30575723

Bonnel C, Legrand B, Simon M, Martinez J, Bantignies JL, Kang YK, Wenger E, Hoh F, Masurier N, Maillard LT C9/12-ribbon-like structure in hybrid peptides alternating α- and thiazole-based γ-amino acids Chemistry 2017,23 (69): 17584-17591 PubMed Id 28990697

Kaplan E, Guichou JF, Chaloin L, Kunzelmann S, Leban N, Serpersu EH, Lionne C Aminoglycoside binding and catalysis specificity of aminoglycoside 2a€³-phosphotransferase IVa: A thermodynamic, structural and kinetic study Biochim Biophys Acta 2016, 1860 (4): 802-813 PubMed Id 26802312

Moarbess G, Guichou JF, Paniagua-Gayraud S, Chouchou A, Marcadet O, Leroy F, Ruedas R, Cuq P, Deleuze-Masquefa C, Bonnet PA New IKK inhibitors: Synthesis of new imidazo[1,2-a]quinoxaline derivatives using microwave assistance and biological evaluation as IKK inhibitors, Eur J Med Chem 2016, 115: 268-274 PubMed Id 27017554

Paoletti J, Assairi L, Gelin M, Huteau V, Nahori MA, Dussurget O, Labesse G, Pochet S 8-Thioalkyl-adenosine derivatives inhibit Listeria monocytogenes NAD kinase through a novel binding mode Eur J Med Chem 2016, 124: 1041-1056 PubMed Id 27783975

Zghaib Z, Guichou JF, Vappiani J, Bec N, Hadj-Kaddour K, Vincent LA, Paniagua-Gayraud S, Larroque C, Moarbess G, Cuq P, Kassab I, Deleuze-Masquefa C, Diab-Assaf M, Bonnet PA New imidazoquinoxaline derivatives: Synthesis, biological evaluation on melanoma, effect on tubulin polymerization and structure-activity relationships Bioorg Med Chem 2016, 24(11):2433-40 PubMed Id 27094151

Bianchin A, Allemand F, Bell A, Chubb AJ, Guichou JF Two crystal structures of the FK506-binding domain of Plasmodium falciparum FKBP35 in complex with rapamycin at high resolution Acta Crystallogr D Biol Crystallogr 2015,71 (6):1319-271319-27 PubMed Id 26057671

Labesse G, Alexandre T, Gelin M, Haouz A, Munier-Lehmann H Crystallographic studies of two variants of Pseudomonas aeruginosa IMPDH with impaired allosteric regulation Acta Crystallogr D Biol Crystallogr 2015, 71(9),1890-9 PubMed Id 26327379

Gelin M, Delfosse V, Allemand F, Hoh F, Sallaz-Damaz Y, Pirocchi M, Bourguet W, Ferrer JL, Labesse G, Guichou JF. Acta Crystallogr D Biol Crystallogr. 2015 71(Pt 8):1777-87. PubMed Id 26249358

Moser von Filseck J, Copic A, Delfosse V, Vanni S, Jackson CL, Bourguet W, Drin G INTRACELLULAR TRANSPORT. Phosphatidylserine transport by ORP/Osh proteins is driven by phosphatidylinositol 4-phosphate, Science 2015, 349 (6246):432-6 PubMed Id 26206936

Naveed H, Hameed US, Harrus D, Bourguet W, Arold ST, Gao X An integrated structure- and system-based framework to identify new targets of metabolites and known drugs Bioinformatics 2015,31(24):3922-9 PubMed Id 26286808

Aguirre C, Brink TT, Guichou JF, Cala O, Krimm I Comparing Binding Modes of Analogous Fragments Using NMR in Fragment-Based Drug Design: Application to PRDX5 PLoS ONE 2014, 9(7): e102300 PubMed Id 25025339

Aguirre C, Ten Brink T, Cala O, Guichou JF, Krimm I Protein-ligand structure guided by backbone and side-chain proton chemical shift perturbations J Biomol NMR 2014, 60(2-3):147-56 PubMed Id 25256941

Amiable C, Paoletti J, Haouz A, Padilla A, Labesse G, Kaminski PA, Pochet S 6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: Synthesis, structural studies and cytotoxic activities Eur J Med Chem, 2014, 85C: 418-437 PubMed Id 25108359 (pôle RMN aussi)

Ahmed-Belkacem A, Guichou JF, Brillet R, Ahnou N, Hernandez E, Pallier C, Pawlotsky JM. Inhibition of RNA binding to hepatitis C virus RNA-dependent RNA polymerase: a new mechanism for antiviral intervention. Nucleic Acids Res. 2014 Aug;42(14):9399-409. PubMed Id 25053847

Birol M, Enchev RI, Padilla A, Stengel F, Aebersold R, Betzi S, Yang Y, Hoh F, Peter M, Dumas C, Echalier A, (2014). Structural and biochemical characterization of the Cop9 signalosome CSN5/CSN6heterodimer. PLoS One. 2014 Aug 21;9(8):e105688. PubMed Id 25144743

Godreuil S, Leban N, Padilla A, Hamel R, Luplertlop N, Chauffour A, Vittecoq M, Hoh F, Thomas F, Sougakoff W, Lionne C, Yssel H, Misse D Aedesin: Structure and Antimicrobial Activity against Multidrug Resistant Bacterial Strains PLoS ONE 2014, 9 (8): e105441 PubMed Id 25108359






 

Pôle Bioinformatique



Fleury C, Gracy J, Gautier MF, Pons JL, Dufayard JF, Labesse G, Ruiz M, de Lamotte F Comprehensive classification of the plant non-specific lipid transfer protein superfamily towards its sequence-structure-function analysis PeerJ 2019,7:e7504 PubMed Id 31428542

Hajj M, De Vita T, Vol C, Renassia C, Bologna JC, Brabet I, Cazade M, Pastore M, Blahos J, Labesse G, Pin JP, Prezeau L Nonclassical Ligand-Independent Regulation of Go Protein by an Orphan Class C G-Protein-Coupled Receptor Mol Pharmacol 2019, 96 (2): 233-246 PubMed Id 31189666

Lopez-Sanchez U, Nicolas G, Richard AC, Maltete D, Charif M, Ayrignac X, Goizet C, Touhami J, Labesse G, Battini JL, Sitbon M Characterization of XPR1/SLC53A1 variants located outside of the SPX domain in patients with primary familial brain calcification Sci Rep 2019, 9(1): 6776 PubMed Id 31043717

Renault P, Louet M, Marie J, Labesse G, Floquet N Molecular Dynamics Simulations of the Allosteric Modulation of the Adenosine A2A Receptor by a Mini-G Protein Sci Rep 2019, 9 (1): 5495 PubMed Id 30940903

Bonneau M, Atyame C, Beji M, Justy F, Cohen-Gonsaud M, Sicard M, Weill M Culex pipiens crossing type diversity is governed by an amplified and polymorphic operon of Wolbachia Nat Commun, 2018,9,1,319 PubMed Id 29358578

Meunier I, Bocquet B, Labesse G, Zeitz C, Defoort-Dhellemmes S, Lacroux A, Mauget-Faysse M, Drumare I, Gamez AS, Mathieu C, Marquette V, Sagot L, Dhaenens CM, Arndt C, Carroll P, Remy-Jardin M, Cohen SY, Sahel JA, Puech B, Audo I, Mrejen S, Hamel CP A new autosomal dominant eye and lung syndrome linked to mutations in TIMP3 gene Sci Rep 2016,6 ,32544 PubMed Id 27601084

Meunier I, Lenaers G, Bocquet B, Baudoin C, Piro-Megy C, Cubizolle A, Quiles M, Jean-Charles A, Cohen SY, Merle H, Gaudric A, Labesse G, Manes G, Pequignot M, Cazevieille C, Dhaenens CM, Fichard A, Ronkina N, Arthur SJ, Gaestel M, Hamel CP A dominant mutation in MAPKAPK3, an actor of p38 signaling pathway, causes a new retinal dystrophy involving Bruch's membrane and retinal pigment epithelium Hum Mol Genet 2016,25(5):916-26 PubMed Id 26744326

Sagnol S, Yang Y, Bessin Y, Allemand F, Hapkova I, Notarnicola C, Guichou JF, Faure S, Labesse G, de Santa Barbara P Homodimerization of RBPMS2 through a new RRM-interaction motif is necessary to control smooth muscle plasticity Nucleic Acids Res 2014, 42(15):10173-84: PubMed Id 25064856 (également pole RMN)


Turapov O, Waddell SJ, Burke B, Glenn S, Sarybaeva AA, Tudo G, Labesse G, Young DI, Young M, Andrew PW, Butcher PD, Cohen-Gonsaud M, Mukamolova GV Antimicrobial treatment improves mycobacterial survival in nonpermissive growth conditions Antimicrob Agents Chemother 2014, 58 (5):2798-806 PubMed Id 24590482

Turapov O, Waddell SJ, Burke B, Glenn S, Sarybaeva AA, Tudo G, Labesse G, Young DI, Young M, Andrew PW, Butcher PD, Cohen-Gonsaud M, Mukamolova GV Oleoyl-Coenzyme A Regulates Interaction of Transcriptional Regulator RaaS (Rv1219c) with DNA in Mycobacteria J Biol Chem 2014, 289(36):25241-9 PubMed Id 25012658




 

Pôle Cheminfo



Loeuillet C, Touquet B, Guichou JF, Labesse G, Sereno D A Tiny Change Makes a Big Difference in the Anti-Parasitic Activities of an HDAC Inhibitor, Int J Mol Sci 2019, 20 :12 PubMed Id 31216674

 

 


 

Pôle Microscopies Optiques



Martiniere A, Fiche JB, Smokvarska M, Mari S, Alcon C, Dumont X, Hematy K, Jaillais Y, Nollmann M, Maurel C Osmotic stress activates two reactive oxygen species pathways with distinct effects on protein nanodomains and diffusion Plant Physiol 2019, 179 ( 4): 1581-1593 PubMed Id 30718348

Nadiras C, Delaleau M, Schwartz A, Margeat E, Boudvillain M A fluorogenic assay to monitor Rho-dependent termination of transcription Biochemistry 2019, 58(7):865-874 PubMed Id 30624903

Platre MP, Bayle V, Armengot L, Bareille J, Marques-Bueno MDM, Creff A, Maneta-Peyret L, Fiche JB, Nollmann M, Miege C, Moreau P, Martiniere A, Jaillais Y Developmental control of plant Rho GTPase nano-organization by the lipid phosphatidylserine Science 2019,364(6435):57-62 PubMed Id 30948546

Quast RB, Fatemi F, Kranendonk M, Margeat E, Truan G Accurate Determination of Human CPR Conformational Equilibrium by smFRET using Dual Orthogonal Non-Canonical Amino Acid Labeling Chembiochem, 2019, 20(5): 659-666 PubMed Id 30427570

Marti-Renom MA, Almouzni G, Bickmore WA, Bystricky K, Cavalli G, Fraser P, Gasser SM, Giorgetti L, Heard E, Nicodemi M, Nollmann M, Orozco M, Pombo A, Torres-Padilla ME Challenges and guidelines toward 4D nucleome data and model standards Nat Genet, 2018, 50 (1):1352-1358 PubMed Id 30262815

M¸ller TC, Hottin J, Clerte C, Zwier JM, Durroux T, Rondard P, Prezeau L, Royer CA, Pin JP, Margeat E, Kniazeff J Oligomerization of a G protein-coupled receptor in neurons controlled by its structural dynamics, Sci Rep 2018, 8(1):10414 PubMed Id 29991736

Tora AS, Rovira X, Cao AM, Cabaye A, Olofsson L, Malhaire F, Scholler P, Baik H, Van Eeckhaut A, Smolders I, Rondard P, Margeat E, Acher F, Pin JP, Goudet C Chloride ions stabilize the glutamate-induced active state of the metabotropic glutamate receptor 3 Neuropharmacology 2018, 140:275-286 PubMed Id 30102917

Vishwakarma RK, Cao AM, Morichaud Z, Perumal AS, Margeat E, Brodolin K Single-molecule analysis reveals the mechanism of transcription activation in Sci Adv 2018, 4:5 PubMed Id 29806016

Walter JC, Dorignac J, Lorman V, Rech J, Bouet JY, Nollmann M, Palmeri J, Parmeggiani A, Geniet F Surfing on Protein Waves: Proteophoresis as a Mechanism for Bacterial Genome Partitioning Phys Rev Lett 2017, 119:2 PubMed Id 28753349

de Torres J, Mivelle M, Moparthi SB, Rigneault H, van Hulst NF, Garcia-Parajo MF, Margeat E, Wenger J Plasmonic Nanoantennas Enable Forbidden Forster Dipole-Dipole Energy Transfer and Enhance the FRET Efficiency Nano Lett 2016, 16(10):6222-6230. PubMed Id 27623052

Faure LM, Fiche JB, Espinosa L, Ducret A, Anantharaman V, Luciano J, Lhospice S, Islam ST, Treguier J, Sotes M, Kuru E, Van Nieuwenhze MS, Brun YV, Theodoly O, L A, Nollmann M, Mignot T The mechanism of force transmission at bacterial focal adhesion complexes Nature 2016, 539(7630):530-535 PubMed Id 27749817

Ferrer M, Clerte C, Chamontin C, Basyuk E, Laine S, Hottin J, Bertrand E, Margeat E, Mougel M Imaging HIV-1 RNA dimerization in cells by multicolor super-resolution and fluctuation microscopies Nucleic Acids Res 2016, 44(16):7922-34. PubMed Id 27280976

Konate K, Lindberg M, Vaissiere A, Jourdan C, Aldrian G, Margeat E, Deshayes S, Boisguerin P Optimisation of vectorisation property: a comparative study for a secondary amphipathic peptide Int J Pharm 2016, 509(1-2):71-84 PubMed Id 27224007

Sanchez A, Cattoni DI, Walter JC, Rech J, Parmeggiani A, Nollmann M, Bouet JY Stochastic Self-Assembly of ParB Proteins Builds the Bacterial DNA Segregation Apparatus Cell Syst 2015, 1(2):163-73 PubMed Id 27135801

Liang J, Lacroix L, Gamot A, Cuddapah S, Queille S, Lhoumaud P, Lepetit P, Martin PG, Vogelmann J, Court F, Hennion M, Micas G, Urbach S, Bouchez O, Nollmann M, Zhao K, Emberly E, Cuvier O Chromatin Immunoprecipitation Indirect Peaks Highlight Long-Range Interactions of Insulator Proteins and Pol II Pausing Mol Cell 2014, 53(4):672-81 PubMed Id 24486021

Moutin E, Compan V, Raynaud F, Clerte C, Bouquier N, Labesse G, Ferguson ML, Fagni L, Royer CA, Perroy J Stoichiometry of scaffold complexes in living neurons - DLC2 as a dimerization engine for GKAP J Cell Sci 2014, 127(Pt 16):3451-62 PubMed Id 24938595 (également Pole Bioinfo).

Olofsson L, Felekyan S, Doumazane E, Scholler P, Fabre L, Zwier JM, Rondard P, Seidel CA, Pin JP, Margeat E Fine tuning of sub-millisecond conformational dynamics controls metabotropic glutamate receptors agonist efficacy Nat Commun 2014 5: 5206 PubMed Id 25323157

Soares E, Schwartz A, Nollmann M, Margeat E, Boudvillain M The RNA-mediated, asymmetric ring regulatory mechanism of the transcription termination Rho helicase decrypted by time-resolved Nucleotide Analog Interference Probing (trNAIP) Nucleic Acids Res 2014, 42(14):9270-84 PubMed Id 25016524




 

Pôle AFM



Ngo G, Felix G, Long J, Costa L, Saavedra O V, Milhiet P E, Devoisselle J M, Guari Y, Larionova J, Chopineau J. A simple approach for controlled deposition of Prussian Q1 blue analogue nanoparticles on a functionalised plasmonic gold surface. New Journal of Chemistry, in press, 2019.

Theodoratou A, Costa L, Bonnet L, Blanc C, Lapinte V, Etienne P, Milhiet P E, Robin J J, Oberdisse, Chopineau J, Pouessel A A, Physico-chemical properties and surface characterization of renewable hybrid nanofilms interacting with model proteins. European Polymer Journal, 111, 2018.

Gumi-Audenis B, Costa L, Redondo-Morata L, Milhiet P E, Sanz F, Felici R, Giannotti M I, Carla F. In-plane molecular organization of hydrated single lipid bilayers: Dppc:cholesterol. Nanoscale, 10:87–92, 2018

Gumi-Audenis B, Costa L, Ferrer-Tasies L, Ratera I, Ventosa N, Sanz F, Giannotti M I, Pulling lipid tubes from supported bilayers unveils the underlying substrate contribution to the membrane mechanics. Nanoscale, 10(30):14763-14770, 2018.

Carrillo-Vazquez JP, Correa-Basurto J, Garcia-Machorro J, Campos-Chamontin C, Rassam P, Ferrer M, Racine PJ, Neyret A, Laine S, Milhiet PE, Mougel M HIV-1 nucleocapsid and ESCRT-component Tsg101 interplay prevents HIV from turning into a DNA-containing virus Nucleic Acids Res 2015, 43 (1): 336-47 PubMed Id 25488808

Greiner VJ, Manin C, Larquet E, Ikhelef N, Greco F, Naville S, Milhiet PE, Ronzon F, Klymchenko A, Mely Y Characterization of the structural modifications accompanying the loss of HBsAg particle immunogenicity Vaccine 2014 32 (9): 1049-54 PubMed Id 24440114

Guyomarc'h F, Zou S, Chen M, Milhiet PE, Godefroy C, Vie V, Lopez C Milk sphingomyelin domains in biomimetic membranes and the role of cholesterol: morphology and nanomechanical properties investigated using AFM and force spectroscopy Langmuir 2014 , 30(22):6516-24 PubMed Id 24835749

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