Liste des publications

2021

• Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures

  Delfosse V, Huet T, Harrus D, Granell M, Bourguet M, Gardia-Parege C, Chiavarina B, Grimaldi M, Le Mevel S, Blanc P, Huang D, Gruszczyk J, Demeneix B, Cianferani S, Fini JB, Balaguer P, Bourguet W, Proc Natl Acad Sci U S A, 2021

2020

• Structural and Functional Specialization of OSBP-Related Proteins

  Delfosse V, Bourguet W, Drin G, Contact, 2020

2019

• Insights into the activation mechanism of human estrogen-related receptor γ by environmental endocrine disruptors

  Thouennon E, Delfosse V, Bailly R, Blanc P, Boulahtouf A, Grimaldi M, Barducci A, Bourguet W, Balaguer P, Cell Mol Life Sci, 2019

• Mechanisms of endocrine disruption through nuclear receptors and related pathways

  Balaguer P, Delfosse V, Bourguet W, Curr Opin Endocr Metab Res, 2019

2017

• Structural and functional evidences for the interactions between nuclear hormone receptors and endocrine disruptors at low doses

  Balaguer P, Delfosse V, Grimaldi M, Bourguet W, C R Biol, 2017

2016

• [The association makes the poison: new perspective on the cocktail effect of xenobiotics and drug interactions]

  Delfosse V, Balaguer P, Bourguet W, Med Sci (Paris), 2016

2015

• Synergistic activation of human pregnane X receptor by binary cocktails of pharmaceutical and environmental compounds

  Delfosse V, Dendele B, Huet T, Grimaldi M, Boulahtouf A, Gerbal-Chaloin S, Beucher B, Roecklin D, Muller C, Rahmani R, Cavailles V, Daujat-Chavanieu M, Vivat V, Pascussi JM, Balaguer P, Bourguet W, Nat Commun, 2015

• Combining `dry' co-crystallization and in situ diffraction to facilitate ligand screening by X-ray crystallography

  Gelin M, Delfosse V, Allemand F, Hoh F, Sallaz-Damaz Y, Pirocchi M, Bourguet W, Ferrer JL, Labesse G, Guichou JF, Acta Crystallogr D Biol Crystallogr, 2015

• Reporter cell lines to evaluate the selectivity of chemicals for human and zebrafish estrogen and peroxysome proliferator activated γ receptors

  Grimaldi M, Boulahtouf A, Delfosse V, Thouennon E, Bourguet W, Balaguer P, Front Neurosci, 2015

• Reporter Cell Lines for the Characterization of the Interactions between Human Nuclear Receptors and Endocrine Disruptors

  Grimaldi M, Boulahtouf A, Delfosse V, Thouennon E, Bourguet W, Balaguer P, Front Endocrinol (Lausanne), 2015

• INTRACELLULAR TRANSPORT. Phosphatidylserine transport by ORP/Osh proteins is driven by phosphatidylinositol 4-phosphate

  Moser von Filseck J, Čopič A, Delfosse V, Vanni S, Jackson CL, Bourguet W, Drin G, Science, 2015

• An Unexpected Mode Of Binding Defines BMS948 as A Full Retinoic Acid Receptor β (RARβ, NR1B2) Selective Agonist

  Nadendla E, Teyssier C, Delfosse V, Vivat V, Krishnasamy G, Gronemeyer H, Bourguet W, Germain P, PLoS ONE, 2015

2014

• Structural and Functional Profiling of Environmental Ligands for Estrogen Receptors

  Delfosse V, Grimaldi M, Cavailles V, Balaguer P, Bourguet W, Environ Health Perspect, 2014

• Nuclear receptor profiling of bisphenol-a and its halogenated analogues

  Delfosse V, Grimaldi M, le Maire A, Bourguet W, Balaguer P, Vitam Horm, 2014

• A structural perspective on nuclear receptors as targets of environmental compounds

  Delfosse V, Maire AL, Balaguer P, Bourguet W, Acta Pharmacol Sin, 2014

2013

• [Towards bisphenols without hormonal effects]

  Balaguer P, Delfosse V, Grimaldi M, Bourguet W, Med Sci (Paris), 2013

2012

• Structural and mechanistic insights into bisphenols action provide guidelines for risk assessment and discovery of bisphenol A substitutes

  Delfosse V, Grimaldi M, Pons JL, Boulahtouf A, le Maire A, Cavailles V, Labesse G, Bourguet W, Balaguer P, Proc Natl Acad Sci U S A, 2012

2011

• Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers

  de Saint-Jean M, Delfosse V, Douguet D, Chicanne G, Payrastre B, Bourguet W, Antonny B, Drin G, J Cell Biol, 2011