Plateforme Intégrée de Biophysique et de Biologie Structurale

Equipement

VP ITC Microcalorimetry

Manager André Padilla
Measure

Determination of affinity constants in protein/protein or protein/ligand or protein/DNA interactions. Determination of the stoichiometry of the biochemical interaction. Determination of thermodynamic constants such the enthalpy and the entropy.

Sample volume 2 ml at around 10-20 uM for the protein, 500 ul at 100-200 uM for the ligand. Duration 3 hours.

 

Isothermal titration calorimeter VP-ITC MicroCal (Malvern InstrumentsTM)

 
Specifications https://www.malvernpanalytical.com/fr/support/product-support/microcal-range/microcal-itc-range/microcal-vp-itc
Room Z2-16@CBS29

Connexion