Plateforme Intégrée de Biophysique et de Biologie Structurale

Platform

Protein crystallisation and structure determination facilities - FRISBI

Technical managers François Hoh , Muriel Gelin
Scientific manager Jean-François Guichou
Permanent staff François Hoh, Jean-François Guichou, Gilles Labesse, Muriel Gelin, Vanessa Delfosse, Albane le Maire, William Bourguet

Automated crystallization screening and optimization using hanging and sitting drop set up at two temperatures (20 deg and 4 deg). Diffraction using synchrotron beamlines and structure elucidation.

Comments For data collection, The CBS has regularly access to several synchrotron like ESRF (Grenoble, FR), Soleil (Gif-sur-Yvette, FR), SLS (Villigen,CH) and ALBA (Barcelona, Spain).
Services

Crystallisation screening and crystallisation conditions optimization

 

Automated visualization of protein crystallization drops

 

Automated pippeting and liquid handling

 

Ligand screening


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