Centre de Biologie Structurale de Montpellier

Actualités

Séminaires

25 Oct

CE CBS 25 Oct 2021 10:00 to 11:00
03 Nov

Conseil Scientifique CBS 03 Nov 2021 15:00 to 17:00
08 Nov

CE CBS 08 Nov 2021 11:00 to 12:00

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Dernières publications

Δ133p53β isoform pro-invasive activity is regulated through an aggregation-dependent mechanism in cancer cells
Arsic N, Slatter T, Gadea G, Villain E, Fournet A, Kazantseva M, Allemand F, Sibille N, Seveno M, de Rossi S, Mehta S, Urbach S, Bourdon JC, Bernado P, Kajava AV, Braithwaite A, Roux P, Nat Commun, 2021
Allosteric modulators enhance agonist efficacy by increasing the residence time of a GPCR in the active state
Cao AM, Quast RB, Fatemi F, Rondard P, Pin JP, Margeat E, Nat Commun, 2021
Misic, a general deep learning-based method for the high-throughput cell segmentation of complex bacterial communities
Panigrahi S, Murat D, Le Gall A, Martineau E, Goldlust K, Fiche JB, Rombouts S, Nollmann M, Espinosa L, Mignot T, Elife, 2021
Discovery of a cryptic site at the interface 2 of TEAD - Towards a new family of YAP/TAZ-TEAD inhibitors
Sturbaut M, Bailly F, Coevoet M, Sileo P, Pugniere M, Liberelle M, Magnez R, Thuru X, Chartier-Harlin MC, Melnyk P, Gelin M, Allemand F, Guichou JF, Cotelle P, Eur J Med Chem, 2021
Programmable receptors enable bacterial biosensors to detect pathological biomarkers in clinical samples
Chang HJ, Zuniga A, Conejero I, Voyvodic PL, Gracy J, Fajardo-Ruiz E, Cohen-Gonsaud M, Cambray G, Pageaux GP, Meszaros M, Meunier L, Bonnet J, Nat Commun, 2021
Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations
Nasrallah C, Cannone G, Briot J, Rottier K, Berizzi AE, Huang CY, Quast RB, Hoh F, Baneres JL, Malhaire F, Berto L, Dumazer A, Font-Ingles J, Gomez-Santacana X, Catena J, Kniazeff J, Goudet C, Llebaria A, Pin JP, Vinothkumar KR, Lebon G, Cell Rep, 2021
Molecular insights into the biased signaling mechanism of the μ-opioid receptor
Cong X, Maurel D, Demene H, Vasiliauskaite-Brooks I, Hagelberger J, Peysson F, Saint-Paul J, Golebiowski J, Granier S, Sounier R, Mol Cell, 2021
RNA imaging in bacteria
Rombouts S, Nollmann M, FEMS Microbiol Rev, 2021
Capsid Proteins Are Necessary for Replication of a Parvovirus
Labadie T, Garcia D, Mutuel D, Ogliastro M, Cambray G, J Virol, 2021
CD82 and Gangliosides Tune CD81 Membrane Behavior
Fernandez L, Malrieu M, Benistant C, Dosset P, Rubinstein E, Odintsova E, Berditchevski F, Milhiet PE, Int J Mol Sci, 2021
Melanotransferrin is efficiently sorted on the surface of exosomes secreted by melanoma cells
Bonhoure A, Henry L, Morille M, Aissaoui N, Bellot G, Stoebner PE, Vidal M, Melanoma Res, 2021
Ligands and DNA in the allosteric control of retinoid receptors function
Germain P, Rochel N, Bourguet W, Essays Biochem, 2021
Proteo3Dnet: a web server for the integration of structural information with interactomics data
Postic G, Andreani J, Marcoux J, Reys V, Guerois R, Rey J, Mouton-Barbosa E, Vandenbrouck Y, Cianferani S, Burlet-Schiltz O, Labesse G, Tuffery P, Nucleic Acids Res, 2021
Comparative Assessment of NMR Probes for the Experimental Description of Protein Folding Pathways with High-Pressure NMR
Van Deuren V, Yang YS, deGuillen K, Dubois C, Royer CA, Roumestand C, Barthe P, Biology (Basel), 2021
The Impact of Space and Time on the Functional Output of the Genome
Nollmann M, Bennabi I, Gotz M, Gregor T, Cold Spring Harb Perspect Biol, 2021
Correlative AFM and fluorescence imaging demonstrate nanoscale membrane remodeling and ring-like and tubular structure formation by septins
Vial A, Taveneau C, Costa L, Chauvin B, Nasrallah H, Godefroy C, Dosset P, Isambert H, Ngo KX, Mangenot S, Levy D, Bertin A, Milhiet PE, Nanoscale, 2021
A Novel Approach to the Facile Growth and Organization of Photothermal Prussian Blue Nanocrystals on Different Surfaces
Ngo G, Felix G, Dorandeu C, Devoisselle JM, Costa L, Milhiet PE, Guari Y, Larionova J, Chopineau J, Nanomaterials (Basel), 2021
Design, Synthesis and Evaluation of a Series of 1,5-Diaryl-1,2,3-triazole-4-carbohydrazones as Inhibitors of the YAP-TAZ/TEAD Complex
Gibault F, Sturbaut M, Coevoet M, Pugniere M, Burtscher A, Allemand F, Melnyk P, Hong W, Rubin BP, Pobbati AV, Guichou JF, Cotelle P, Bailly F, ChemMedChem, 2021
Exploring the conformational space of a receptor for drug design: An ERα case study
Schneider M, Pons JL, Labesse G, J Mol Graph Model, 2021
The diversity of molecular interactions involving intrinsically disordered proteins: A molecular modeling perspective
Clerc I, Sagar A, Barducci A, Sibille N, Bernado P, Cortes J, Comput Struct Biotechnol J, 2021
Mechanical Control of Cell Migration by the Metastasis Suppressor Tetraspanin CD82/KAI1
Ordas L, Costa L, Lozano A, Chevillard C, Calovoulos A, Kantar D, Fernandez L, Chauvin L, Dosset P, Doucet C, Heron-Milhavet L, Odintsova E, Berditchevski F, Milhiet PE, Benistant C, Cells, 2021
Single-molecule FRET on its way to structural biology in live cells
Quast RB, Margeat E, Nat Methods, 2021
The study of the determinants controlling Arpp19 phosphatase-inhibitory activity reveals an Arpp19/PP2A-B55 feedback loop
Labbe JC, Vigneron S, Mechali F, Robert P, Roque S, Genoud C, Goguet-Rubio P, Barthe P, Labesse G, Cohen-Gonsaud M, Castro A, Lorca T, Nat Commun, 2021
Protein-Ligand Binding Volume Determined from a Single 2D NMR Spectrum with Increasing Pressure
Skvarnavičius G, Toleikis Z, Michailovienė V, Roumestand C, Matulis D, Petrauskas V, J Phys Chem B, 2021
Arginine multivalency stabilizes protein/RNA condensates
Paloni M, Bussi G, Barducci A, Protein Sci, 2021
Cryo-electron microscopy structure of the antidiuretic hormone arginine-vasopressin V2 receptor signaling complex
Bous J, Orcel H, Floquet N, Leyrat C, Lai-Kee-Him J, Gaibelet G, Ancelin A, Saint-Paul J, Trapani S, Louet M, Sounier R, Demene H, Granier S, Bron P, Mouillac B, Sci Adv, 2021
A Comparative Study of Human and Zebrafish Pregnane X Receptor Activities of Pesticides and Steroids Using In Vitro Reporter Gene Assays
Creusot N, Garoche C, Grimaldi M, Boulahtouf A, Chiavarina B, Bourguet W, Balaguer P, Front Endocrinol (Lausanne), 2021
Synergy and allostery in ligand binding by HIV-1 Nef
Aldehaiman AM, Momin AA, Restouin A, Wang L, Shi X, Aljedani S, Opi S, Lugari A, Shahul Hameed UF, Ponchon L, Morelli X, Huang M, Dumas C, Collette Y, Arold S, Biochem J, 2021
Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures
Delfosse V, Huet T, Harrus D, Granell M, Bourguet M, Gardia-Parege C, Chiavarina B, Grimaldi M, Le Mevel S, Blanc P, Huang D, Gruszczyk J, Demeneix B, Cianferani S, Fini JB, Balaguer P, Bourguet W, Proc Natl Acad Sci U S A, 2021
Folding of phosphodiester-linked donor-acceptor oligomers into supramolecular nanotubes in water
Perez de Carvasal K, Aissaoui N, Vergoten G, Bellot G, Vasseur JJ, Smietana M, Morvan F, Chem Commun (Camb), 2021

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Les équipes du CBS

Structure, dynamique et fonctions des biomolécules par RMN

Christian Roumestand et Nathalie Declerck
Structure et fonction de protéines hautement flexibles

Pau Bernadó et Nathalie Sibille
Biologie structurale multi-échelles (BSME)

Patrick Bron
Atelier de Biologie-Chimie-Informatique Structurale

Gilles Labesse
Les récepteurs nucléaires, intégrateurs de signaux endogènes et environnementaux

William Bourguet et Albane Le Maire
Modélisation moléculaire multi-échelle

Alessandro Barducci
Mécanismes de la ségrégation de l’ADN et du remodelage

Marcelo Nollmann
Physique et mécanique des systèmes biologiques

Manouk Abkarian et Francesco Pedaci
Biophysique Intégrative des Membranes

Pierre-Emmanuel Milhiet et Emmanuel Margeat
Biologie Synthétique

Jérôme Bonnet et Martin Cohen-Gonsaud
Modélisation moléculaire multi-échelle

Alessandro Barducci
Structure du chromosome et recombinaison en méiose

Thomas Robert
Génomique fonctionnelle et synthétique

Guillaume Cambray
Structure et fonction du récepteur AhR

Jakub Gruszczyk

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