Adapting the Charge Flipping algorithm to biological macromolecule diffraction data :
* ab initio determination of protein crystal structures at atomic resolution
* heavy atom or anomalous scatterers substructure determination

Dumas C. & van der Lee A. (2008) "Macromolecular structure solution by charge flipping", Acta Cryst D64, 864-873.

Palatinus L. & Chapuis G. (2007) "SUPERFLIP, a computer program for the solution of crystal structures by charge flipping in arbitrary dimensions", J. Appl. Cryst.40,786-790.