Plateforme Intégrée de Biophysique et de Biologie Structurale

Service

High-Speed Atomic Force Microscopy

Goal

Real-time visualization of biomolecules activity at high spatial-temporal resolution by High-Speed AFM (HS-AFM).

Our HS-AFM can acquire AFM images up to 10 images/seconds, allowing for dynamic tracking of slow biomolecules activity.

 

Elongation of single protofibril (white arrows) is shown in time lapses. Deciphering the Structure, Growth and Assembly of Amyloid-Like Fibrils Using High-Speed Atomic Force Microscopy. Milhiet, P. E., Yamamoto, D., Berthoumieu, O., Dosset, P., Le Grimellec, C., Verdier, J. M., ... & Ando, T. (2010). PLoS One, 5(10), e13240. Speed = 1 image/second.

 
Equipement

High-Speed AFM

       

Read more ...
       

Connexion