Genomes are heavily biased by evolutionary processes.
This greatly limits how we can approach sequence-activity-fitness relationships.
We use DNA synthesis to precisely program sequence variants that, taken together, are most informative of a biological process.
We develop multiplex, deep-sequencing-based phenotyping assays to rapidly measure phenotypic consequences at different levels of organization.
Analysis of resulting designer datasets provides unique opportunities to decipher biological complexities.
Please take a deeper look at our current projects in our team RESEARCH tab above for more details.
We currently have two openings for post-doctoral or research engineer positions.